Abstract: This invention relates to radiopaque polymers and to their use, particularly in the manufacture of medical devices and in methods of medical treatment, including therapeutic embolization. In particular embodiments the present disclosure relates to a hydrophilic polymer comprising pendent groups which a phenyl ring is substituted with one or more iodine groups and one or more non-iodine groups as described in more detail herein.

Abstract: A hydrophilic polymer comprising pendent groups of the formula I: Wherein: W is independently selected from —OH, —COOH, —SO3H, —OPO3H, —O—(C1-4alkyl), —O—(C1-4alkyl)OH, —O—(C1-4alkyl)R2, —O—(C2H5O)qR1—(C?O)—O—C1-4alkyl and —O—(C?O)C1-4alkyl; or a group —BZ; wherein —OH, COOH, O—PO3H and SO3H maybe in the form of a pharmaceutically acceptable salt; wherein: B is a bond, or a straight branched alkanediyl, oxyalkylene, alkylene oxaalkylene, or alkylene (oligooxalkylene) group, optionally containing one or more fluorine substituents; and Z is an ammonium, phosphonium, or sulphonium phosphate or phosphonate ester zwitterionic group; X is either a bond or a linking group having 1 to 8 carbons and optionally 1 to 4 heteroatoms selected from O, N and S; G is a coupling group through which the group of the formula I is coupled to the polymer and is selected from ether, ester, amide, carbonate, carbamate, 1,3 dioxolone, and 1,3 dioxane; R1 is H or C1-4 alkyl; R2 is —COOH, —SO3H, or —OPO3H2 q is an integer from 1 to 4;

Abstract: One aspect of the present disclosure pertains to a connector for conveying a suspension of particles through a system, comprising: a housing (10) comprising an internal cavity (12) and a first passageway (14) for conveying fluid; two or more inlet conduits (16a, 16b, 16c, 16d) formed in the housing and arranged radially with respect to a longitudinal axis of the first passageway; and a rotatable component (18) received in the internal cavity of the housing and rotatable about the longitudinal axis of the first passageway such that a continuous flow path can be established between the first passageway and a selected inlet conduit; wherein an angle between each of the inlet conduits and the first passageway (22) is greater than 90 degrees. Other aspects pertain to systems that employ such a connector and to methods of using such systems.

Abstract: A hydrophilic polymer comprising pendent groups of the formula I: Wherein: W is independently selected from —OH, —COOH, —SO3H, —OPO3H, —O—(C1-4alkyl), —O—(C1-4alkyl)OH, —O—(C1-4alkyl)R2, —O—(C2H5O)qR1—(C?O)—O—C1-4alkyl and —O—(C?O)C1-4alkyl; or a group —BZ; wherein —OH, COOH, O—PO3H and SO3H maybe in the form of a pharmaceutically acceptable salt; wherein: B is a bond, or a straight branched alkanediyl, oxyalkylene, alkylene oxaalkylene, or alkylene (oligooxalkylene) group, optionally containing one or more fluorine substituents; and Z is an ammonium, phosphonium, or sulphonium phosphate or phosphonate ester zwitterionic group; X is either a bond or a linking group having 1 to 8 carbons and optionally 1 to 4 heteroatoms selected from O, N and S; G is a coupling group through which the group of the formula I is coupled to the polymer and is selected from ether, ester, amide, carbonate, carbamate, 1,3 dioxolone, and 1,3 dioxane; R1 is H or C1-4 alkyl; R2 is —COOH, —SO3H, or —OPO3H2 q is an integer from to 4; n

Abstract: A polymer having a backbone comprising a polyhydroxylated polymer cross linked by a C3 to C8 diacid.