Abstract: A device includes a device input, an output connector configured to connect to a current loop, and current loop transmitter circuitry. The current loop transmitter circuitry receives, via the device input, an input from a dry contact switch, and translates a state of the dry contact switch to a current loop current. The current loop transmitter circuitry transmits the current loop current via the output connector through the current loop.

Abstract: Systems and methods provide for deployment of an integrated development environment configured to include one or more tools associated with specific code portions being executed within the integrated development environment. A user may provide a request to access one or more projects and definition files associated with the one or more projects may be evaluated to determine one or more tools used for execution of the source code of the one or more projects. The one or more tools may be automatically incorporated into whichever integrated development environment the user selects to ensure proper execution of the code without manual updates or installation by the user.

Abstract: A user interface is described, such as a graphical user interface (GUI), operable to receive a representation of a security policy expressed in a first policy language, where that security policy will be supported by policy evaluation engines (or other such components) that are configured to operate using security policies expressed using a second (different) policy language. The representation of the security policy is persisted in a data store in accordance with the first policy language. Subsequently, in response to receiving a request to access a resource, a second representation of the security policy is generated by translating the content of the security policy into a second policy language that is associated with the policy evaluation engine. The second representation of the security policy is then evaluated by the policy evaluation engine to grant or deny access to the resource.

Abstract: A user interface is described, such as a graphical user interface (GUI), operable to receive a representation of a security policy expressed in a first policy language, where that security policy will be supported by policy evaluation engines (or other such components) that are configured to operate using security policies expressed using a second (different) policy language. The representation of the security policy is persisted in a data store in accordance with the first policy language. Subsequently, in response to receiving a request to access a resource, a second representation of the security policy is generated by translating the content of the security policy into a second policy language that is associated with the policy evaluation engine. The second representation of the security policy is then evaluated by the policy evaluation engine to grant or deny access to the resource.

Abstract: A user interface is described, such as a graphical user interface (GUI), operable to receive a representation of a security policy expressed in a first policy language, where that security policy will be supported by policy evaluation engines (or other such components) that are configured to operate using security policies expressed using a second (different) policy language. The representation of the security policy is persisted in a data store in accordance with the first policy language. Subsequently, in response to receiving a request to access a resource, a second representation of the security policy is generated by translating the content of the security policy into a second policy language that is associated with the policy evaluation engine. The second representation of the security policy is then evaluated by the policy evaluation engine to grant or deny access to the resource.

Abstract: A method of predicting a lung cancer patient's response to FGFR inhibitors is disclosed herein, particularly in patients with squamous cell lung cancer.

Abstract: A method for controlling crosstalk, power and yield in nanometer-technology integrated circuits (“ICs”) is based on a performance driven space optimization technique that minimizes the coupling capacitance between the interconnecting wires. Given a routed IC design, virtual compression-springs are inserted between all the elements of the design creating a mesh of springs. The design is then perturbed, or shaken, by transforming the spring system into a minimum-energy problem, a solution for which reduces or eliminates crosstalk violations, minimizes power and increases yield as the springs reach minimum energy state. In a described method, the primitives of a given IC layout are defined in terms of object points. In a first step, a mesh of virtual compression springs connecting all the layout primitives is generated from the object points.

Abstract: The present invention provides methods and compositions for electroporation-mediated gene transfer to cancer cells. The transfected cancer cells are genetically modified to express one or more therapeutic proteins. In certain embodiments, the cancer cells are modified to express one or more cytokines capable of enhancing the immunogenicity of the transfected cancer cell. Administering the transfected cancer cell to a subject will lead to enhanced immune-cell mediated killing of tumors. Accordingly, the present invention provides methods and compositions for improved treatment and prevention of cancer and other hyperproliferative diseases.

Abstract: Methods for loading an antigen-presenting cell with one ore more antigens are disclosed. Methods for the treatment and prevention of a disease in a subject using an antigen-presenting cell that has been electroporated with a composition of one or more antigens. Composition of one or more antigens comprises one or more antigens of a hyperproliferative cell, a microorganism or a microorganism-infected cell are also disclosed. In addition, compositions of antigen-presenting cells that have been loaded with one or more antigens of a hyperproliferative cell, a microorganism-infected cell or a microorganism using electroporation are disclosed.

Abstract: A device for securing a snowboard is provided including a shackle accessory in the form of a bracket for attaching a securing mechanism, with or without a lock, to a snowboard. The bracket of the present invention collapses for ease of portability. Also provided is an alternate embodiment wherein the securing mechanism can be used as a carrying strap.

Abstract: An automatic pedal is composed of a bracket member adapted to be supported by the pedal arm of a conventional bicycle, and a peg member adapted to be supported by a conventional riding shoe. The bracket member has an aperture configured to receive the peg member and to secure the peg member to the bracket when the bicycle rider places the riding shoe in a riding position. The aperture is configured to release the peg member upon the riding shoe being turned out of the riding position. The peg member is provided with two mating portions which allow the riding position (the position at which the peg member is secured to the riding shoe) to be adjusted.

Abstract: A peg is securable to each shoe and is releasably attachable to a bracket secured to each bicycle pedal. The bracket is securable to a conventional bicycle pedal for example by using screws and screw holes normally provided on conventional pedals for mounting reflectors, or the like, thereon. The peg is securable to the bottom of a conventional riding shoe for example by using the screw holes and screws normally provided on conventional riding shoes for mounting a cleat, or the like, thereon. The peg is shaped so as to fit into an aperture formed in the bracket and to constantly abut the edge of the aperture upon insertion. In one embodiment, the peg is provided with spiral shaped slots and the bracket with tabs, which operate together to releasably attach the peg to the bracket in a screw-threading manner.

Abstract: The method of mesh generation comprises a two-step automatic process that requires no user input once a geometric representation of the object has been provided to the apparatus. In the method, the object geometry is first defined in terms of object (subdomain) points, wherein each subdomain is a separate geometric region of the object such as a printed circuit board, a hole in the board, and a component mounted on the board. Bounding points defining a frame around the object geometry are then generated for producing a mesh consisting of at least one element. From the object points and the bounding points an initial mesh of elements is automatically generated according to a unique algorithm. In the second step of the process, each element in this mesh is then individually examined to determine if it meets a predetermined standard of acceptability and, if not, is refined.

Abstract: A circuit breaker structure having a faster trip unit characterized by a circuit breaker operator and a trip unit comprising a coil, a core, and an armature, a flux concentrating plate spaced from and on the side of the armature opposite the core and for concentrating the magnetic field between the core and the armature, and a hold-back bracket having extending from and retaining the armature in a spaced position from the core so as to cause the magnetic field lines to flow through the bracket and the armature.