Abstract: Aspects of the disclosure provide for controlling an autonomous vehicle to enter a driveway. As an example, an instruction to pickup or drop off a passenger at a location may be received. It may be determined that the vehicle is arriving in a lane on an opposite side of a street as the location, the lane having a traffic direction opposite to a traffic direction of a lane adjacent to the location. A difficulty score to maneuver the vehicle to the lane adjacent to the location may be determined, and the difficulty score may be compared to a predetermined difficulty score. Based on the comparison, it may be determined to an available driveway on the same side of the street as the location. The vehicle may be controlled to enter the available driveway.

Abstract: Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides: wherein R1, R2, R3, R4, R5, R6, Q1, Q2, J, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound. N-oxide, salt or composition.

Abstract: Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides: wherein R1, R2, R3, R4, R5, R6, Q1, Q2, J, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound, N-oxide, salt or composition.

Abstract: An automated robotic printing device for additive manufacturing or three-dimensional printing of an engineered cementitious composite (ECC) structure is provided. The device has a feeding system and an automated extrusion system configured to receive the ECC composition from the feeding system and deposit the ECC composition onto a target. The automated extrusion system comprising at least one robotic device comprising a tiltable and steerable deposition head that comprises an extrusion nozzle having a substantially rectangular opening and at least one shaping blade at a terminal end to shape and deposit the cementitious composition onto a target. Methods of additive manufacturing of a structure from the ECC compositions are also provided.

Abstract: A multilayer substrate material configured to be applied to a back surface of an upholstery or mattress textile fabric and a front surface configured to contact a user of the upholstery or mattress textile fabric. The multilayer substrate material includes protector, adhesive, film and backcoat layers. The adhesive layer is applied to the protector layer and formed of a number of discrete and non-continuous regions. The film layer is applied to the adhesive layer. The number of discrete and non-continuous regions include an interface between the protector layer and the film layer such that the protector layer touches the film layer at the interface. The backcoat layer is applied to the film layer and includes a non-acrylic binder and a flame retardant material. The number of discrete and non-continuous regions form a number of non-adhesive regions therebetween configured to not resist flexing of the protector, film and backcoat layers.

Abstract: Angiopoietin-like protein (ANGPTL)3/8 fusion proteins are disclosed. Nucleic acid constructs encoding ANGPTL3/8 fusion proteins also are disclosed. Methods of making and using the same also are disclosed, especially for generating antibodies against ANGPTL3 and/or ANGPTL8.

Abstract: The present invention relates to fusion proteins comprising an insulin receptor agonist fused to a human IgG Fc region through the use of a peptide linker, and the use of such fusion proteins in the treatment of diabetes. The fusion protein of the present invention has an extended time action profile and is useful for providing basal glucose control for an extended period of time.

Abstract: Disclosed are compounds of Formula 1, N-oxides of the compounds and salts of the compounds and N-oxides: wherein R1, R2, R3, R4, R5, R6, Q1, Q2, J, Y1, and Y2 are as defined in the disclosure. Also disclosed are compositions containing the compounds, N-oxides and salts, and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of such a compound, N-oxide, salt or composition.

Abstract: Angiopoietin-like protein (ANGPTL)3/8 complexes and antibodies are disclosed, where the antibodies bind to and thereby neutralize ANGPTL3/8 complexes. Pharmaceutical compositions also are disclosed that include one or more anti-ANGPTL3/8 complex antibodies herein in a pharmaceutically acceptable carrier. Methods of making and using the same also are disclosed, especially for increase lipoprotein lipase activity and lowering triglycerides. In this manner, the compounds and compositions may be used in treating lipid metabolism-related and glucose metabolism-related diseases and disorders.

Abstract: The present invention relates to neuregulin (NRG) 4 compounds and methods of treatment with NRG4 compounds.

Abstract: A remote microphone system for a vehicle may include at least one physical microphone arranged within a vehicle cabin configured to generate an error signal at a virtual microphone location within the vehicle, a database configured to maintain a look up table of premeasured seat positions and associated transfer functions, and a processor. The processor may be configured to receive a seat position indicative of a seat location within the vehicle, and apply a transfer function associated with the premeasured position to a primary noise signal of the at least one physical microphone to generate the error signal.

Abstract: Methods to increase structural performance, strength, and durability of textile-reinforced composite materials are provided. The textile reinforcement may be knitted, for example, in a flat bed weft knitting machine. The method may include pre-stressing a textile reinforcement preform by applying tension. A polymeric precursor may be introduced to the pre-stressed textile reinforcement preform. The polymeric precursor may then be cured or consolidated, followed by releasing of the applied tension to form the composite article comprising polymer and the pre-stressed textile reinforcement. In other aspects, a composite article is provided that has a pre-stressed textile reinforcement structure and a cured polymer. The textile reinforcement may be a knitted, lightweight, seamless, unitary structure.

Abstract: The present invention relates to fusion proteins comprising an insulin receptor agonist fused to a human IgG Fc region through the use of a peptide linker, and the use of such fusion proteins in the treatment of diabetes. The fusion protein of the present invention has an extended time action profile and is useful for providing basal glucose control for an extended period of time.

Abstract: Disclosed herein is a refined PUFA oil with an enhanced palatability comparing to the same PUFA oil without refinement. Also disclosed is a food composition for a companion animal or a food for human consumption wherein said food composition comprises the above refined PUFA oil and thus having enhanced palatability. Further disclosed herein is a method for manufacturing the above-mentioned refined PUFA oil wherein said method comprises the step of deodorization.

Abstract: Angiopoietin-like protein (ANGPTL)3/8 complexes and antibodies are disclosed, where the antibodies bind to and thereby neutralize ANGPTL3/8 complexes. Pharmaceutical compositions also are disclosed that include one or more anti-ANGPTL3/8 complex antibodies herein in a pharmaceutically acceptable carrier. Methods of making and using the same also are disclosed, especially for increase lipoprotein lipase activity and lowering triglycerides. In this manner, the compounds and compositions may be used in treating lipid metabolism-related and glucose metabolism-related diseases and disorders.

Abstract: The present invention relates to neuregulin (NRG) 4 compounds and methods of treatment with NRG4 compounds.

Abstract: Valve trim apparatus having multiple fluid flow control members are disclosed herein. An example valve trim apparatus includes a primary valve seat and a first flow control member having a cavity and a first seating surface. The first flow control member is movable relative to the primary valve seat to control fluid flow between an inlet and an outlet of the fluid valve. A second flow control member is disposed within the cavity. The second flow control member is slidably coupled relative to the first flow control member. A secondary valve seat is coupled to the first flow control member. The second flow control member is to move relative to the secondary valve seat to throttle a fluid flow across the secondary valve seat.

Abstract: A finished composite material having a film layer, a fibrous material layer and a discontinuous adhesive region layer situated between the film layer and the fibrous material layer. The discontinuous adhesive region layer adheres the film layer to the fibrous material layer. The discontinuous adhesive layer forms a number of discrete and non-continuous regions including an interface between the film layer and the fibrous material layer such that the film layer touches the fibrous material layer at the interface. The number of discrete and non-continuous regions forms a number of non-adhesive regions therebetween configured to not resist flexing of the film layer and the fibrous material layer. The finished composite material further includes an upholstery or mattress textile fabric substrate having a thickness of 0.5 to 2.0 millimeters. The front surface of the upholstery or mattress textile fabric substrate is configured to contact a user of the fabric substrate.

Abstract: Condensed algal residue solubles turned out to be a beneficial feed ingredient for feeding animals, in particular for improving the growth performance of beef cattle.