Patents by Inventor Jonathan Whitney Gunn

Jonathan Whitney Gunn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAGNETIC NANOPARTICLE AND METHOD FOR IMAGING T CELLS
    Publication number: 20160193369
    Abstract: The present invention provides nanoparticles having a core comprising a magnetic material and having a surface, where the surface may be operatively linked to an antigenic peptide-major histocompatibility complex (MHC) monomer. The antigenic peptide-MHC monomer may then be recognized by a T cell receptor. These nanoparticles may further comprise a signal-generating label, such as a fluorophore. Methods employing nanoparticles of the present invention may involve magnetic resonance imaging and/or fluorescence detection, such that cell imaging and localization are performed.
    Type: Application
    Filed: March 10, 2016
    Publication date: July 7, 2016
    Applicants: University of Washington, Fred Hutchinson Cancer Research Center
    Inventors: Miqin Zhang, Jonathan Whitney Gunn, Cassian Yee
  • PRE-TARGETED NANOPARTICLE SYSTEM AND METHOD FOR LABELING BIOLOGICAL PARTICLES
    Publication number: 20130309171
    Abstract: Nanoparticle system and method for labeling, detecting, and treating biological particles. In the method, targeting functionality (fusion protein) and therapeutic/imaging modalities (nanoparticle) are separated.
    Type: Application
    Filed: April 29, 2013
    Publication date: November 21, 2013
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Miqin Zhang, Oliver W. Press, Jonathan Whitney Gunn, Steven I. Park
  • MAGNETIC NANOPARTICLE AND METHOD FOR IMAGING T CELLS
    Publication number: 20110250146
    Abstract: The present invention provides nanoparticles having a core comprising a magnetic material and having a surface, where the surface may be operatively linked to an antigenic peptide-major histocompatibility complex (MHC) monomer. The antigenic peptide-MHC monomer may then be recognized by a T cell receptor. These nanoparticles may further comprise a signal-generating label, such as a fluorophore. Methods employing nanoparticles of the present invention may involve magnetic resonance imaging and/or fluorescence detection, such that cell imaging and localization are performed.
    Type: Application
    Filed: October 8, 2010
    Publication date: October 13, 2011
    Applicants: FRED HUTCHINSON CANCER RESEARCH CENTER, UNIVERSITY OF WASHINGTON
    Inventors: Miqin Zhang, Jonathan Whitney Gunn, Cassian Yee
  • Nanoparticles having reactive ester groups covalently coupled thereto and related methods
    Patent number: 7666394
    Abstract: A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: February 23, 2010
    Assignee: University of Washington
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • NANOPARTICLES HAVING REACTIVE ESTER GROUPS COVALENTLY COUPLED THERETO AND RELATED METHODS
    Publication number: 20090060846
    Abstract: A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
    Type: Application
    Filed: November 5, 2008
    Publication date: March 5, 2009
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • Magnetic nanoparticle compositions and methods
    Patent number: 7462446
    Abstract: A nanoparticle having a core comprising a magnetic material and surface to which are covalently coupled a plurality of silane moieties, wherein each silane moiety comprises a polyalkylene oxide moiety. The nanoparticle can further include a targeting agent, a targeting agent and a diagnostic agent, or a targeting agent and a therapeutic agent. Methods for using the nanoparticle to detect and treat tissues of interest.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: December 9, 2008
    Assignee: University of Washington
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn