Patents by Inventor Jonathan William Larson

Jonathan William Larson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20240132939
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: December 12, 2023
    Publication date: April 25, 2024
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20240093271
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: November 20, 2023
    Publication date: March 21, 2024
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20240002910
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: September 12, 2023
    Publication date: January 4, 2024
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20230086845
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: November 22, 2022
    Publication date: March 23, 2023
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20220213530
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: January 13, 2022
    Publication date: July 7, 2022
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • MANIPULATION OF MICROFLUIDIC DROPLETS
    Publication number: 20220143617
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 12, 2022
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
  • Manipulation of microfluidic droplets
    Patent number: 11268887
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: March 8, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • Digital analyte analysis
    Patent number: 11254968
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: February 22, 2022
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • Methods for forming mixed droplets
    Patent number: 11077415
    Abstract: The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: August 3, 2021
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Yevgeny Yurkovetsky, Darren Roy Link, Jonathan William Larson
  • MANIPULATION OF MICROFLUIDIC DROPLETS
    Publication number: 20200225129
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Application
    Filed: January 2, 2020
    Publication date: July 16, 2020
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • Manipulation of microfluidic droplets
    Patent number: 10527529
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: January 7, 2020
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Benjamin J. Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • METHODS FOR FORMING MIXED DROPLETS
    Publication number: 20190134581
    Abstract: The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet.
    Type: Application
    Filed: November 5, 2018
    Publication date: May 9, 2019
    Inventors: Yevgeny Yurkovetsky, Darren Roy Link, Jonathan William Larson
  • Methods for forming mixed droplets
    Patent number: 10155207
    Abstract: The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: December 18, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Yevgeny Yurkovetsky, Darren R. Link, Jonathan William Larson
  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20180057863
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: August 28, 2017
    Publication date: March 1, 2018
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • MANIPULATION OF MICROFLUIDIC DROPLETS
    Publication number: 20170336306
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Application
    Filed: August 10, 2017
    Publication date: November 23, 2017
    Inventors: Benjamin J. Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Roy Link, Mark Weary
  • Digital analyte analysis
    Patent number: 9745617
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: August 29, 2017
    Assignee: Raindance Technologies, Inc.
    Inventors: Jonathan William Larson, Qun Zhong, Darren R. Link
  • Manipulation of microfluidic droplets
    Patent number: 9733168
    Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: August 15, 2017
    Assignee: Raindance Technologies, Inc.
    Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
  • METHODS FOR FORMING MIXED DROPLETS
    Publication number: 20160346748
    Abstract: The invention generally relates to methods for forming mixed droplets. In certain embodiments, methods of the invention involve forming a droplet, and contacting the droplet with a fluid stream, wherein a portion of the fluid stream integrates with the droplet to form a mixed droplet.
    Type: Application
    Filed: June 2, 2016
    Publication date: December 1, 2016
    Inventors: Yevgeny Yurkovetsky, Darren R. Link, Jonathan William Larson
  • Digital analyte analysis
    Patent number: 9441266
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Grant
    Filed: February 22, 2013
    Date of Patent: September 13, 2016
    Assignee: Raindance Technologies, Inc.
    Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
  • DIGITAL ANALYTE ANALYSIS
    Publication number: 20160222433
    Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
    Type: Application
    Filed: February 9, 2016
    Publication date: August 4, 2016
    Inventors: Jonathan William Larson, Qun Zhong, Darren R. Link