Patents by Inventor Jonathan Yee-Ting Hsu

Jonathan Yee-Ting Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR PREDICTING REPAIR OUTCOMES IN GENETIC ENGINEERING
    Publication number: 20200040329
    Abstract: The specification provides a machine-learning model which predicts, based on input that can include a given target DNA sequence and a CRISPR/Cas cut site location, repair genotype outcomes associated with template-free repair processes (e.g., MMEJ or NHEJ) acting on Cas9-induced double-stranded DNA breaks. The specification further provides for the use of a machine-learning model for conducting genome editing based on a template-free CRISPR/Cas system, including the selection of an appropriate guide RNA (gRNA) to achieve a desired repaired genotype outcome.
    Type: Application
    Filed: August 12, 2019
    Publication date: February 6, 2020
    Inventors: David K. Gifford, Max Walt Shen, Jonathan Yee-Ting Hsu