Abstract: Methods for receiving a patient mark in an implanted device. A patient may experience symptoms that indicative of a neurological event or are common precursors to more severe clinical symptoms. The patient may activate a patient activator. Activation of the patient activator can cause the patient activator to transmit the patient mark to an implanted device. The implanted device may adjust physiological data being stored in response to the patient mark, including data before and after the patient mark. The patient mark may be used to fine tune the detection algorithms and otherwise tune the detection capability of the implanted device and may also be used as an aid in statistical analysis of the stored physiological data.

Abstract: An assembly for sensing physiologic signals and delivering monopolar stimulation therapy includes a pulse generator, a lead body that is coupled to the pulse generator and includes a first lead, at least one stimulating electrode coupled to the first lead and adapted to receive stimulating pulses from the pulse generator, and a remote electrode that is coupled to the pulse generator and positioned away from the pulse generator.

Abstract: A medical device system that includes a brain monitoring element, cardiac monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a cardiac signal from the cardiac monitoring element. The processor is further configured to determine at least one reference point for a brain event time period by evaluation of the brain signal. The processor further identifies a first portion of the cardiac signal based on the at least one reference point of the brain event time period.

Abstract: Methods of generating an extended cluster are disclosed. A first cluster including data representative of a first signal indicative of an abnormal physiological symptom is generated. A second signal is detected as representing a second abnormal physiological symptom and the second abnormal physiological symptom continues after the first abnormal physiological symptom ends. An extended cluster including the data from the first signal and the second signal is generated that extends from the time when the first abnormal physiological symptom occurs to the time when the second abnormal physiological symptom ends. The first and the extended cluster may include data of both the first and second signals the entire period of the clusters. If desired, the first signal or the second signal may be provided from a sensor implanted in a patient's brain tissue.

Abstract: A medical device system includes a brain monitoring element, cardiopulmonary monitoring element, therapy module and a processor. The processor is configured to activate the therapy module upon detection of a cardiopulmonary event in the cardiopulmonary signal. The processor is further configured to monitor the brain signal and communicate to the therapy module to change the cardiopulmonary triggered therapeutic output to the brain based upon the brain monitoring. Methods of treating a person with a neurological disorder are also provided.

Abstract: A medical device system includes a brain monitoring element, cardiac monitoring element, therapy module and a processor. The processor is configured to activate the therapy module upon detection of a cardiac event in the cardiac signal. The processor is further configured to monitor the brain signal and communicate to the therapy module to change the cardiac triggered therapeutic output to the brain based upon the brain monitoring. A method of treating a person with a neurological disorder is also provided.

Abstract: A medical device system that includes a brain monitoring element, cardiac monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a cardiac signal from the cardiac monitoring element. The processor is further configured to compare the brain signal to the cardiac signal. A method of comparing a brain signal to a cardiac signal is also provided.

Abstract: A medical device system for comparing a cardiopulmonary signal to a brain signal. In one embodiment of the invention, a medical device system is provided that includes a brain monitoring element, respiratory monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a respiratory signal from the respiratory monitoring element. The processor is further configured to compare the brain signal to the respiratory signal. Methods of comparing a brain signal to a cardiopulmonary signal are also provided.