Patents by Inventor Jonathon Green

Jonathon Green has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High throughput, optical method and system for determining the effect of a test substance on non-contiguous living cells
    Patent number: 9053352
    Abstract: A rapid and efficient method and apparatus for detecting electrophysiologic, proarrhythmic, contractile, and other effects of substances such as compounds and drugs in native cellular cardiac preparations, the preparations representing an integrated cell-based pharmacologic response is disclosed. More specifically, a method to (1) rapidly and efficiently detect and verify the effects of chemicals, compounds and drugs on cardiac repolarization, contractility, and excitability using optically based techniques and customized simulation protocols, and (2) rapidly and efficiently screen and select compounds for electrophysiologic and proarrhythmic effects on cardiac myocytes is disclosed.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: June 9, 2015
    Assignee: AbbVie Inc.
    Inventors: Jonathan D. Trumbull, Gary A. Gintant, Stanislaw Kantor, Jeffrey Yen Pan, Gilbert J. Diaz, Jonathon Green, Zhi Su, Jeffrey A. Olson
  • HIGH THROUGHPUT, OPTICAL METHOD AND SYSTEM FOR DETERMINING THE EFFECT OF A TEST SUBSTANCE ON NON-CONTIGUOUS LIVING CELLS
    Publication number: 20120134570
    Abstract: A rapid and efficient method and apparatus for detecting electrophysiologic, proarrhythmic, contractile, and other effects of substances such as compounds and drugs in native cellular cardiac preparations, the preparations representing an integrated cell-based pharmacologic response is disclosed. More specifically, a method to (1) rapidly and efficiently detect and verify the effects of chemicals, compounds and drugs on cardiac repolarization, contractility, and excitability using optically based techniques and customized simulation protocols, and (2) rapidly and efficiently screen and select compounds for electrophysiologic and proarrhythmic effects on cardiac myocytes is disclosed.
    Type: Application
    Filed: November 11, 2011
    Publication date: May 31, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Jonathan D. Trumbull, Gary A. Gintant, Stanislaw Kantor, Jeffrey Yen Pan, Gilbert J. Diaz, Jonathon Green, Zhi Su, Jeffrey A. Olson