Patents by Inventor Jonathon H. Pinter

Jonathon H. Pinter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
    Patent number: 11661628
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: May 30, 2023
    Assignee: Takara Bio USA, Inc.
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov
  • Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
    Patent number: 11492663
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: November 8, 2022
    Assignee: Takara Bio USA, Inc.
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov
  • Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
    Patent number: 10837049
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: November 17, 2020
    Assignee: Takara Bio USA, Inc.
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov
  • Amplification and Analysis of Whole Genome and Whole Transcriptome Libraries Generated by a DNA Polymerization Process
    Publication number: 20190271033
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Application
    Filed: February 15, 2019
    Publication date: September 5, 2019
    Inventors: Emmanuel KAMBEROV, Tong SUN, Eric BRUENING, Jonathon H. PINTER, Irina SLEPTSOVA, Takao KURIHARA, Vladimir L. MAKAROV
  • AMPLIFICATION AND ANALYSIS OF WHOLE GENOME AND WHOLE TRANSCRIPTOME LIBRARIES GENERATED BY A DNA POLYMERIZATION PROCESS
    Publication number: 20180030522
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Application
    Filed: August 10, 2017
    Publication date: February 1, 2018
    Inventors: Emmanuel KAMBEROV, Tong SUN, Eric BRUENING, Jonathon H. PINTER, Irina SLEPTSOVA, Takao KURIHARA, Vladimir L. MAKAROV
  • AMPLIFICATION AND ANALYSIS OF WHOLE GENOME AND WHOLE TRANSCRIPTOME LIBRARIES GENERATED BY A DNA POLYMERIZATION PROCESS
    Publication number: 20160355879
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Application
    Filed: July 22, 2016
    Publication date: December 8, 2016
    Applicant: Rubicon Genomics, Inc.
    Inventors: Emmanuel KAMBEROV, Tong SUN, Eric BRUENING, Jonathon H. PINTER, Irina SLEPTSOVA, Takao KURIHARA, Vladimir L. MAKAROV
  • Methods and compositions for generating and amplifying DNA libraries for sensitive detection and analysis of DNA methylation
    Patent number: 8440404
    Abstract: The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries.
    Type: Grant
    Filed: March 3, 2005
    Date of Patent: May 14, 2013
    Assignee: Rubicon Genomics
    Inventors: Vladimir L. Makarov, Emmanuel Kamberov, Tong Sun, Jonathon H. Pinter, Brendan J. Tarrier, Eric E. Bruening, Takao Kurihara, Tim Tesmer, Joseph M'Mwirichia
  • SUBSTANTIALLY NON-SELF COMPLEMENTARY PRIMERS
    Publication number: 20130085083
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Application
    Filed: June 4, 2012
    Publication date: April 4, 2013
    Applicant: Rubicon Genomics
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov
  • Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
    Patent number: 8206913
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Grant
    Filed: March 3, 2010
    Date of Patent: June 26, 2012
    Assignee: Rubicon Genomics, Inc.
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov
  • Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
    Patent number: 7718403
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: May 18, 2010
    Assignee: Rubicon Genomics, Inc.
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov
  • In vitro DNA immortalization and whole genome amplification using libraries generated from randomly fragmented DNA
    Publication number: 20040209299
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome in a non-biased manner utilizing adaptor-attached randomly generated fragments following modification of the DNA ends prior to the adaptor attachment. In an additional aspect of the present invention, there are methods and compositions for whole genome amplification regarding a one-step endonuclease cleavage and linker ligation reaction.
    Type: Application
    Filed: March 8, 2004
    Publication date: October 21, 2004
    Applicant: RUBICON GENOMICS, INC.
    Inventors: Jonathon H. Pinter, Takao Kurihara, Irina Sleptsova, Eric Bruening, William Ziehler, Vladimir L. Makarov
  • Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process
    Publication number: 20040209298
    Abstract: The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
    Type: Application
    Filed: March 8, 2004
    Publication date: October 21, 2004
    Inventors: Emmanuel Kamberov, Tong Sun, Eric Bruening, Jonathon H. Pinter, Irina Sleptsova, Takao Kurihara, Vladimir L. Makarov