Patents by Inventor Jonel TREBICKA

Jonel TREBICKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating portal hypertension
    Patent number: 9872851
    Abstract: The present invention provides methods for treating or preventing portal hypertension comprising administering to a patient in need of such treatment or prevention at least one Rev-erb modulating agent (REMA) in an amount effective to treat or prevent said portal hypertension. The REMA can be SR6452 or a related compound, such as SR9009 or SR9011. The amount of the REMA administered can comprises a quantity sufficient to modulate Rev-erb? expression, activity, and/or subcellular location and/or to inhibit or reverse hepatic stellate cell (HSC) activation and contractility.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: January 23, 2018
    Assignee: THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY
    Inventors: Ting Li, Laura Schrum, Jonel Trebicka
  • Methods of Treating Portal Hypertension
    Publication number: 20150313871
    Abstract: The present invention provides methods for treating or preventing portal hypertension comprising administering to a patient in need of such treatment or prevention at least one Rev-erb modulating agent (REMA) in an amount effective to treat or prevent said portal hypertension. The REMA can be SR6452 or a related compound, such as SR9009 or SR9011. The amount of the REMA administered can comprises a quantity sufficient to modulate Rev-erb? expression, activity, and/or subcellular location and/or to inhibit or reverse hepatic stellate cell (HSC) activation and contractility.
    Type: Application
    Filed: December 12, 2013
    Publication date: November 5, 2015
    Inventors: Ting LI, Laura SCHRUM, Jonel TREBICKA