Patents by Inventor Jong Buhm Park
Jong Buhm Park has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11835734Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: March 9, 2022Date of Patent: December 5, 2023Assignee: REBUS BIOSYSTEMS, INC.Inventors: Chun-Sheu Lee, Jong Buhm Park
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Publication number: 20220197045Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: ApplicationFiled: March 9, 2022Publication date: June 23, 2022Inventors: Chun-Sheu Lee, Jong Buhm Park
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Patent number: 11300801Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: September 14, 2020Date of Patent: April 12, 2022Assignee: Rebus Biosystems, Inc.Inventors: Chun-Sheu Lee, Jong Buhm Park
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Publication number: 20210096387Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: ApplicationFiled: September 14, 2020Publication date: April 1, 2021Inventors: Chun-Sheu Lee, Jong Buhm Park
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Patent number: 10802292Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: September 11, 2019Date of Patent: October 13, 2020Assignee: Optical Biosystems, Inc.Inventors: Chun-Sheu Lee, Jong Buhm Park
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Publication number: 20200004040Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: ApplicationFiled: September 11, 2019Publication date: January 2, 2020Inventors: Chun-Sheu Lee, Jong Buhm Park
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Patent number: 10429665Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: August 24, 2017Date of Patent: October 1, 2019Assignee: Optical Biosystems, Inc.Inventors: Chun-Sheu Lee, Jong Buhm Park
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Patent number: 10353036Abstract: It is an aspect of the present disclosure to provide an MRI apparatus configured to and a method to acquire a sectional image of an object and implement a reduced Field of View (FOV) from which aliasing is removed by using a saturation pulse sequence that suppresses a magnetic resonance (MR) signal at a given position, and a method of controlling the same. An MRI apparatus may include: a sequence controller controlling a scanner to apply an unsaturation pulse sequence and a saturation pulse sequence to the object; and a data processor configured to acquire a first image by receiving an MR signal from the object to which the unsaturation pulse sequence is applied, acquire a second image by receiving an MR signal from the object to which the saturation pulse sequence is applied, and generate a difference image between the first image and the second image.Type: GrantFiled: December 21, 2016Date of Patent: July 16, 2019Assignee: SAMSUNG ELECTRONICS CO., LTD.Inventors: Sang Young Zho, Jong Buhm Park, Sung Pil Jung
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Patent number: 10168405Abstract: Provided are a method and apparatus for processing a magnetic resonance (MR) image of an object including first and second materials on a magnetic resonance imaging (MRI) apparatus by using multi-parameter mapping including applying to the object a plurality of radio frequency (RF) pulses separated by a first repetition time and a second repetition time, the first repetition time and the second repetition time being determined based on the first material and the second material; undersampling first MR signals corresponding to the first material and second MR signals corresponding to the second material in a K-space; and performing matching between the undersampled first and the undersampled second MR signals and a signal model for the multi-parameter mapping to determine attribute values corresponding to the first and the second materials at at least one point in an MR image of the object.Type: GrantFiled: November 11, 2015Date of Patent: January 1, 2019Assignees: SAMSUNG ELECTRONICS CO., LTD., INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITYInventors: Lae-hoon Kang, Dong-hyun Kim, Min-oh Kim, Dong-yeob Han, Do-sik Hwang, Yong-sup Park, Jong-buhm Park, Jae-sung Lee
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Publication number: 20180136481Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: ApplicationFiled: August 24, 2017Publication date: May 17, 2018Inventors: Chun-Sheu Lee, Jong Buhm Park
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Patent number: 9772505Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: March 2, 2016Date of Patent: September 26, 2017Assignee: Optical Biosystems, Inc.Inventors: Chun-Sheu Lee, Jong Buhm Park
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Publication number: 20170176560Abstract: It is an aspect of the present disclosure to provide an MRI apparatus configured to and a method to acquire a sectional image of an object and implement a reduced Field of View (FOV) from which aliasing is removed by using a saturation pulse sequence that suppresses a magnetic resonance (MR) signal at a given position, and a method of controlling the same. An MRI apparatus may include: a sequence controller controlling a scanner to apply an unsaturation pulse sequence and a saturation pulse sequence to the object; and a data processor configured to acquire a first image by receiving an MR signal from the object to which the unsaturation pulse sequence is applied, acquire a second image by receiving an MR signal from the object to which the saturation pulse sequence is applied, and generate a difference image between the first image and the second image.Type: ApplicationFiled: December 21, 2016Publication date: June 22, 2017Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Sang Young ZHO, Jong Buhm PARK, Sung Pil JUNG
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Patent number: 9465228Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: March 19, 2010Date of Patent: October 11, 2016Assignee: Optical Biosystems, Inc.Inventors: Chun-Sheu Lee, Jong Buhm Park
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Patent number: 9458501Abstract: Nucleic acid microparticles are sequenced by performing a sequencing reaction on the microparticles using one or more reagents, selectively exciting the microparticles in an excitation pattern, optically imaging the microparticles at a resolution insufficient to resolve individual microparticles, and processing the optical images of the microparticles using information on the excitation pattern to determine the presence or absence of the optical signature, which indicates the sequence information of the nucleic acid. An apparatus for optical excitation of the microparticles comprises an interference pattern generation module that splits a first laser beam into second and third laser beams and generates the excitation pattern for selectively exciting the microparticles by interference between the second and third laser beams.Type: GrantFiled: May 5, 2014Date of Patent: October 4, 2016Assignee: Optical Biosystems, Inc.Inventors: Stanley S. Hong, Jekwan Ryu, Jong Buhm Park
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Publication number: 20160178921Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: ApplicationFiled: March 2, 2016Publication date: June 23, 2016Inventors: Chun-Sheu Lee, Jong Buhm Park
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Publication number: 20160131729Abstract: Provided are a method and apparatus for processing a magnetic resonance (MR) image of an object including first and second materials on a magnetic resonance imaging (MRI) apparatus by using multi-parameter mapping including applying to the object a plurality of radio frequency (RF) pulses separated by a first repetition time and a second repetition time, the first repetition time and the second repetition time being determined based on the first material and the second material; undersampling first MR signals corresponding to the first material and second MR signals corresponding to the second material in a K-space; and performing matching between the undersampled first and the undersampled second MR signals and a signal model for the multi-parameter mapping to determine attribute values corresponding to the first and the second materials at at least one point in an MR image of the object.Type: ApplicationFiled: November 11, 2015Publication date: May 12, 2016Applicants: SAMSUNG ELECTRONICS CO., LTD., INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITYInventors: Lae-hoon KANG, Dong-hyun KIM, Min-oh KIM, Dong-yeob HAN, Do-sik HWANG, Yong-sup PARK, Jong-buhm PARK, Jae-sung LEE
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Publication number: 20140242683Abstract: Nucleic acid microparticles are sequenced by performing a sequencing reaction on the microparticles using one or more reagents, selectively exciting the microparticles in an excitation pattern, optically imaging the microparticles at a resolution insufficient to resolve individual microparticles, and processing the optical images of the microparticles using information on the excitation pattern to determine the presence or absence of the optical signature, which indicates the sequence information of the nucleic acid. An apparatus for optical excitation of the microparticles comprises an interference pattern generation module that splits a first laser beam into second and third laser beams and generates the excitation pattern for selectively exciting the microparticles by interference between the second and third laser beams.Type: ApplicationFiled: May 5, 2014Publication date: August 28, 2014Applicant: LightSpeed Genomics, Inc.Inventors: Stanley S. Hong, Jekwan Ryu, Jong Buhm Park
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Patent number: 8759077Abstract: Nucleic acid microparticles are sequenced by performing a sequencing reaction on the microparticles using one or more selectively exciting the microparticles in an excitation pattern, optically imaging the microparticles at a resolution insufficient to resolve individual microparticles, and processing the optical images of the microparticles using information on the excitation pattern to determine the presence or absence of the optical signature, which indicates the sequence information of the nucleic acid. An apparatus for optical excitation of the microparticles comprises an optical fiber delivering a first laser beam, and an interference pattern generation module coupled to the optical fiber. The interference pattern generation module splits the first laser beam into second and third laser beams and generates the excitation pattern for selectively exciting the microparticles by interference between the second and third laser beams.Type: GrantFiled: August 28, 2007Date of Patent: June 24, 2014Assignee: Lightspeed Genomics, Inc.Inventors: Stanley S. Hong, Jekwan Ryu, Jong Buhm Park
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Patent number: 8502867Abstract: A synthetic aperture optics (SAO) imaging method minimizes the number of selective excitation patterns used to illuminate the imaging target, based on the objects' physical characteristics corresponding to spatial frequency content from the illuminated target and/or one or more parameters of the optical imaging system used for SAO. With the minimized number of selective excitation patterns, the time required to perform SAO is reduced dramatically, thereby allowing SAO to be used with DNA sequencing applications that require massive parallelization for cost reduction and high throughput. In addition, an SAO apparatus optimized to perform the SAO method is provided. The SAO apparatus includes a plurality of interference pattern generation modules that can be arranged in a half-ring shape.Type: GrantFiled: March 19, 2010Date of Patent: August 6, 2013Assignee: LightSpeed Genomics, Inc.Inventor: Jong Buhm Park
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Patent number: 8222040Abstract: Nucleic acid microparticles are sequenced by performing a sequencing reaction on the microparticles using one or more reagents, selectively exciting the microparticles in an excitation pattern, optically imaging the microparticles at a resolution insufficient to resolve individual microparticles, and processing the optical images of the microparticles using information on the excitation pattern to determine the presence or absence of the optical signature, which indicates the sequence information of the nucleic acid. An apparatus for optical excitation of the microparticles comprises an optical fiber delivering a first laser beam, and an interference pattern generation module coupled to the optical fiber. The interference pattern generation module splits the first laser beam into second and third laser beams and generates the excitation pattern for selectively exciting the microparticles by interference between the second and third laser beams.Type: GrantFiled: August 28, 2007Date of Patent: July 17, 2012Assignee: LightSpeed Genomics, Inc.Inventors: Stanley S. Hong, Jekwan Ryu, Jong Buhm Park