Patents by Inventor JONG-HUN IM

JONG-HUN IM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEMS GAS SENSOR AND MANUFACTURING METHOD THEREOF
    Publication number: 20240110883
    Abstract: Disclosed are a MEMS gas sensor and a manufacturing method thereof. The MEMS gas sensor includes a substrate having a recess, a membrane disposed in the recess and having a through-hole configured to expose a portion of a top surface of the substrate, which is disposed at a central portion of the recess, sensing electrodes disposed in the membrane, and a sensing layer disposed on each of bottom and top surfaces of the membrane and disposed in the through-hole.
    Type: Application
    Filed: September 11, 2023
    Publication date: April 4, 2024
    Inventors: Seungeon MOON, JEONG HUN KIM, Jong Pil IM
  • Biomolecule imaging method using aptamer
    Patent number: 11499156
    Abstract: A composition for imaging a tumorous disease region includes a fluorescence- or radioactive isotope-labeled ERBB2 aptamer, wherein the ERBB2 aptamer labeled with a radioactive isotope or a fluorescent dye is used to image the tumorous disease region in vivo. The composition may include a labeled hybridized aptamer comprising an aptamer represented as formula 1 hybridized with a labeled-ODN represented as formula 2.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: November 15, 2022
    Assignee: INTEROLIGO CORPORATION
    Inventors: Jung Hwan Lee, Jong In Kim, Jong Hun Im, Jong Ook Lee, Jin Woo Kim
  • Aptamer-drug conjugate and use thereof
    Patent number: 11458120
    Abstract: A cancer targeted therapeutic agent includes a drug-linker-AS1411 structure. The drug may be selected from monomethyl auristatin E (MMAE), monomethyl auristatin F (MMAF), cytarabine, gemcitabine, maytansine, DM1, DM4, calicheamicin and a derivative thereof, doxorubicin, duocarmycin and a derivative thereof, pyrrolobenzodiazepine (PBD), SN-38, a-amanitin, or a tubulysin analog.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: October 4, 2022
    Assignee: INTEROLIGO CORPORATION
    Inventors: Jung Hwan Lee, Jong Hun Im, Jong In Kim
  • Aptamer against insulin receptor and pharmaceutical compostion containing the same
    Patent number: 10724039
    Abstract: The present disclosure relates to a DNA aptamer which specifically binds to an insulin receptor, and a composition for treating diabetes and a composition for diagnosing diabetes which contain the same as an active ingredient, and the aptamer is characterized by being able to treat and diagnose diabetes more effectively than side effects caused by insulin such as increased incidence of cancer and atherosclerosis by having a different binding mechanism from existing insulin.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: July 28, 2020
    Assignees: Posco, Postech Academy-Industry Foundation
    Inventors: Sung Ho Ryu, Na-Oh Yunn, Jong Hun Im, Ara Koh, Eun Ju Oh, Sehoon Park, Jiyoun Lee, Sung Key Jang, Seungmin Han, Youndong Kim
  • BIOMOLECULE IMAGING METHOD USING APTAMER
    Publication number: 20200157543
    Abstract: A composition for imaging a tumorous disease region includes a fluorescence- or radioactive isotope-labeled ERBB2 aptamer, wherein the ERBB2 aptamer labeled with a radioactive isotope or a fluorescent dye is used to image the tumorous disease region in vivo. The composition may include a labeled hybridized aptamer comprising an aptamer represented as formula 1 hybridized with a labeled-ODN represented as formula 2.
    Type: Application
    Filed: April 25, 2018
    Publication date: May 21, 2020
    Inventors: Jung Hwan LEE, Jong In KIM, Jong Hun IM, Jong Ook LEE, Jin Woo KIM
  • APTAMER-DRUG CONJUGATE AND USE THEREOF
    Publication number: 20190358202
    Abstract: A cancer targeted therapeutic agent includes a drug-linker-AS1411 structure. The drug may be selected from monomethyl auristatin E (MMAE), monomethyl auristatin F (MMAF), cytarabine, gemcitabine, maytansine, DM1, DM4, calicheamicin and a derivative thereof, doxorubicin, duocarmycin and a derivative thereof, pyrrolobenzodiazepine (PBD), SN-38, a-amanitin, or a tubulysin analog.
    Type: Application
    Filed: December 4, 2017
    Publication date: November 28, 2019
    Inventors: Jung Hwan LEE, Jong Hun IM, Jong In KIM
  • APTAMER AGAINST INSULIN RECEPTOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
    Publication number: 20190032060
    Abstract: The present disclosure relates to a DNA aptamer which specifically binds to an insulin receptor, and a composition for treating diabetes and a composition for diagnosing diabetes which contain the same as an active ingredient, and the aptamer is characterized by being able to treat and diagnose diabetes more effectively than side effects caused by insulin such as increased incidence of cancer and atherosclerosis by having a different binding mechanism from existing insulin.
    Type: Application
    Filed: May 3, 2016
    Publication date: January 31, 2019
    Inventors: Sung Ho RYU, Na-Oh YUNN, Jong Hun IM, Ara KOH, Eun Ju OH, Sehoon PARK, Jiyoun LEE, Sung Key JANG, Seungmin HAN, Youndong KIM
  • Aptamer for periostin and anti-cancer composition including same
    Patent number: 9650638
    Abstract: This disclosure relates to DNA aptamer specifically binding to periostin, which is cancer-related protein, a composition for inhibiting cancer and/or cancer metastasis and/or a composition for diagnosis of cancer and/or cancer metastasis, comprising the same as an active ingredient, wherein the aptamer has different binding mechanism from the existing antibodies, and thus, may inhibit and diagnose cancer/cancer metastasis more effectively.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: May 16, 2017
    Assignees: UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY), POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Pann-Ghill Suh, Ii Shin Kim, Yu Jin Lee, Youn Dong Kim, Young Chan Chae, Jong Hun Im, Sung Ho Ryu
  • Aptamer which selectively binds to ERBB2 receptor and uses thereof
    Patent number: 9309515
    Abstract: Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: April 12, 2016
    Assignees: POSTECH ACADEMY-INDUSTRY FOUNDATION, KOREA FOOD & DRUG ADMINISTRATION
    Inventors: Jung Hwan Lee, Young Chan Chae, Youngdong Kim, Hyungu Kang, Jong Hun Im, Jong In Kim, Ki Seok Kim, Sung Key Jang, Il Ung Oh, Min Jeong Choi, Won Jun Kang
  • APTAMER FOR PERIOSTIN AND ANTI-CANCER COMPOSITION INCLUDING SAME
    Publication number: 20150337309
    Abstract: This disclosure relates to DNA aptamer specifically binding to periostin, which is cancer-related protein, a composition for inhibiting cancer and/or cancer metastasis and/or a composition for diagnosis of cancer and/or cancer metastasis, comprising the same as an active ingredient, wherein the aptamer has different binding mechanism from the existing antibodies, and thus, may inhibit and diagnose cancer/cancer metastasis more effectively.
    Type: Application
    Filed: November 12, 2012
    Publication date: November 26, 2015
    Inventors: Pann-Ghill SUH, Il Shin KIM, Yu Jin LEE, Youn Dong KIM, Young Chan CHAE, Jong Hun IM, Sung Ho RYU
  • Method of treating hyperproliferation of cells using a nucleolin specific aptamer
    Patent number: 9018186
    Abstract: Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: April 28, 2015
    Assignee: Postech Academy-Industry Foundation
    Inventors: Jung Hwan Lee, Soon Hag Kim, Mi-Jin Kwon, Hyungu Kang, Sung Ho Ryu, Jong In Kim, Youndong Kim, Young Chan Chae, Sung Key Jang, Jong Hun Im, Sun Hak Lee, Hye Jung Lee, Eun Jung Jang, Ki Seok Kim
  • Method of diagnosing cancer using a nucleolin specific aptamer
    Patent number: 9018185
    Abstract: Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: April 28, 2015
    Assignee: Postech Academy-Industry Foundation
    Inventors: Jung Hwan Lee, Soon Hag Kim, Mi-Jin Kwon, Hyungu Kang, Sung Ho Ryu, Jong In Kim, Youndong Kim, Young Chan Chae, Sung Key Jang, Jong Hun Im, Sun Hak Lee, Hye Jung Lee, Eun Jung Jang, Ki Seok Kim
  • APTAMER WHICH SELECTIVELY BINDS TO ERBB2 RECEPTOR AND USES THEREOF
    Publication number: 20150005368
    Abstract: Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.
    Type: Application
    Filed: August 10, 2011
    Publication date: January 1, 2015
    Applicants: KOREA FOOD & DRUG ADMINISTRATION, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Jung Hwan Lee, Young Chan Chae, Youndong Kim, Hyungu Kang, Jong Hun Im, Jong In Kim, Ki Seok Kim, Sung Key Jang, II Ung Oh, Min Jeong Choi, Won Jun Kang
  • Method of treating hyperproliferation of cells using a nucleolin specific aptamer
    Publication number: 20140213636
    Abstract: Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
    Type: Application
    Filed: September 24, 2013
    Publication date: July 31, 2014
    Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: JUNG HWAN LEE, SOON HAG KIM, MI-JIN KWON, HYUNGU KANG, SUNG HO RYU, JONG IN KIM, YOUNDONG KIM, YOUNG CHAN CHAE, SUNG KEY JANG, JONG HUN IM, SUN HAK LEE, HYE JUNG LEE, EUN JUNG JANG, KI SEOK KIM
  • Aptamer sandwich assays
    Patent number: 8785132
    Abstract: The present invention provides methods for identifying the plurality of aptamers that bind to different sites of a target molecule and methods for using the same, for example, in sandwich assays. In particular, the plurality of aptamers binding to different sites of the target molecules is identified from a library of aptamers identified from the same SELEX process.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: July 22, 2014
    Assignee: Postech Academy-Industry Foundation
    Inventors: Young-Chan Chae, Youn-Dong Kim, Jung-Hwan Lee, Ki-Seok Kim, Dong-II Han, Bum-Su Park, Seung-Jin Lee, Jong-Hun Im, Jong-In Kim, Sung-Ho Ryu, Sung-Key Jang
  • Method of diagnosing cancer using a nucleolin specific aptamer
    Publication number: 20140093886
    Abstract: Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
    Type: Application
    Filed: September 24, 2013
    Publication date: April 3, 2014
    Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: JUNG HWAN LEE, SOON HAG KIM, MI-JIN KWON, HYUNGU KANG, SUNG HO RYU, JONG IN KIM, YOUNDONG KIM, YOUNG CHAN CHAE, SUNG KEY JANG, JONG HUN IM, SUN HAK LEE, HYE JUNG LEE, EUN JUNG JANG, KI SEOK KIM
  • Nucleolin specific aptamer and use thereof
    Patent number: 8569252
    Abstract: Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
    Type: Grant
    Filed: April 14, 2010
    Date of Patent: October 29, 2013
    Assignees: Postech Academy-Industry Foundation, Posco
    Inventors: Jung-Hwan Lee, Soon-Hag Kim, Mi-Jin Kwon, Hyun-Gu Kang, Sung-Ho Ryu, Jong-In Kim, Youn-Dong Kim, Young-Chan Chae, Sung-Key Jang, Jong-Hun Im, Sun-Hak Lee, Hye-Jung Lee, Eun-Jung Jang, Ki-Seok Kim
  • APTAMER SANDWICH ASSAYS
    Publication number: 20110262922
    Abstract: The present invention provides methods for identifying the plurality of aptamers that bind to different sites of a target molecule and methods for using the same, for example, in sandwich assays. In particular, the plurality of aptamers binding to different sites of the target molecules is identified from a library of aptamers identified from the same SELEX process.
    Type: Application
    Filed: April 22, 2011
    Publication date: October 27, 2011
    Applicants: POSCO, POSTECH ACADEMY-INDUSTRY FOUNDATION
    Inventors: Young-Chan CHAE, Youn-Dong Kim, Jung-Hwan Lee, Ki-Seok Kim, Dong-II Han, Bum-Su Park, Seung-Jin Lee, Jong-Hun Im, Jong-In Kim, Sung-Ho Ryu, Sung-Key Jang
  • Nucleolin Specific Aptamer and Use thereof
    Publication number: 20100317723
    Abstract: Improved G-rich oligonucleotide (GRO) aptamers specific to nucleolin, a method of preparing the aptamers, and a use of the aptamers for diagnosing and/or treating a nucleolin-associated disease, are provided.
    Type: Application
    Filed: April 14, 2010
    Publication date: December 16, 2010
    Applicants: POSTECH ACADEMY-INDUSTRY FOUDATION, POSCO
    Inventors: JUNG-HWAN LEE, SOON-HAG KIM, MI-JIN KWON, HYUN-GU KANG, SUNG-HO RYU, JONG-IN KIM, YOUN-DONG KIM, YOUNG-CHAN CHAE, SUNG-KEY JANG, JONG-HUN IM, SUN-HAK LEE, HYE-JUNG LEE, EUN-JUNG JANG, KI-SEOK KIM