Abstract: The present invention relates to: an antibody to T cell Immunoreceptor with Ig and Tyrosine-Based Inhibitory Motif Domains (TIGIT), or an antigen-binding fragment thereof; a nucleic acid encoding same; a vector carrying the nucleic acid; a cell transformed with the vector; a method for producing the antibody or the antigen-binding fragment thereof; and a composition and a composition for combined administration, which comprise same and are for preventing or treating cancer.

Abstract: The present invention provides a pharmaceutical composition for inhibiting the metastasis of cancer, comprising, as an active ingredient, an antibody that specifically binds to an epidermal growth factor receptor, and a method for inhibiting the metastasis of cancer using the composition. The composition or the method is effective in inhibiting the invasion of various gastric cancer cell lines induced by EGFR ligands. Therefore, the pharmaceutical composition can be usefully used for inhibiting the metastasis of cancer.

Abstract: Disclosed are epitopes of the epidermal growth factor receptor (EGFR) and the use thereof. The epitopes are highly preserved, and located in the domain closely related to binding with an epidermal growth factor (EGF). Therefore, vaccine compositions comprising the epitopes or compositions comprising antibodies to the epitopes may efficiently block a signal transduction caused by binding of EGF and EGRF, and thus can be highly valuably used in treating various diseases such as cancer. An antibody bound to the epitopes of the present invention may efficiently inhibit binding of various EGFR ligands such as not only EGF but also TGF-?, AR, BTC, EPR and HB-EGF, with EGFR, and therefore can be used in treating various diseases resulting from an activation of EGFR caused by binding not only with EGF but also with other EGFR ligands.

Abstract: The present invention provides a pharmaceutical composition for inhibiting the metastasis of cancer, comprising, as an active ingredient, an antibody that specifically binds to an epidermal growth factor receptor, and a method for inhibiting the metastasis of cancer using the composition. The composition or the method is effective in inhibiting the invasion of various gastric cancer cell lines induced by EGFR ligands. Therefore, the pharmaceutical composition can be usefully used for inhibiting the metastasis of cancer.

Abstract: A method and apparatus for analyzing elastography of tissue using ultrasound waves, wherein elastography information of tissue in a region of interest (ROI) is analyzed by irradiating ultrasound waves for diagnosis towards the ROI to which a shear wave is induced from an ultrasound probe, receiving echo ultrasound waves, and acquiring three-dimensional (3D) ultrasound images with respect to the ROI.

Abstract: A surgical implement and a manipulation system including the surgical implement may include at least one instrument including at least one joint portion. The joint portion may include a first part, a second part connected to the first part, and a force applying element for applying a force for bending (or rotating) the second part. A distance between a joint point and a force application point where a force is applied may be greater than a diameter of at least one of the first part and the second part. The instrument may further include a second joint portion spaced apart from the joint portion, and a surgical tool connected to an end portion of the second joint portion. The manipulation system may include a supporting structure, at least one instrument supported by the supporting structure, and an operating device for operating the instrument.

Abstract: A method and apparatus for analyzing elastography of tissue using ultrasound waves, wherein elastography information of tissue in a region of interest (ROI) is analyzed by irradiating ultrasound waves for diagnosis towards the ROI to which a shear wave is induced from an ultrasound probe, receiving echo ultrasound waves, and acquiring three-dimensional (3D) ultrasound images with respect to the ROI.

Abstract: Disclosed are epitopes of the epidermal growth factor receptor (EGFR) and the use thereof. The epitopes are highly preserved, and located in the domain closely related to binding with an epidermal growth factor (EGF). Therefore, vaccine compositions comprising the epitopes or compositions comprising antibodies to the epitopes may efficiently block a signal transduction caused by binding of EGF and EGRF, and thus can be highly valuably used in treating various diseases such as cancer. An antibody bound to the epitopes of the present invention may efficiently inhibit binding of various EGFR ligands such as not only EGF but also TGF-?, AR, BTC, EPR and HB-EGF, with EGFR, and therefore can be used in treating various diseases resulting from an activation of EGFR caused by binding not only with EGF but also with other EGFR ligands.

Abstract: A surgical instrument includes an extension portion having a surgical tool at an end thereof, and a head portion connected to the extension portion and actuating the surgical tool. In the surgical instrument, the extension portion includes a first extension portion connected to the head portion, a second extension portion having an elbow joint portion that is bending-actuated by a rigid rod that is reciprocated in a lengthwise direction by the head portion, and a connection portion connecting the first and second extension portions at an angle.

Abstract: A tire pressure monitoring system (TPMS) is provided. The TPMS includes: a plurality of sensors which output sensing signals, the plurality of sensors including a printable pressure sensor which senses an air pressure of a tire, and a temperature sensor which senses an air temperature inside the tire; a signal processor which is configured to process the sensing signals output by the plurality of sensors; a wireless power receiver which is configured to receive energy from a power source and output power; and a rechargeable battery which is configured to be charged by the power output by the wireless receiver and supply power to the plurality of sensors to sense the air pressure of the tire and the air temperature inside the tire.

Abstract: The present invention relates to epitopes of the epidermal growth factor receptor (EGFR) and the use thereof. The epitopes provided by the present invention are highly preserved, and located in the domain closely related to binding with an epidermal growth factor (EGF). Therefore, vaccine compositions comprising the epitopes or compositions comprising antibodies to the epitopes may efficiently block a signal transduction caused by binding of EGF and EGRF, and thus can be highly valuably used in treating various diseases such as cancer. An antibody bound to the epitopes of the present invention may efficiently inhibit binding of various EGFR ligands such as not only EGF but also TGF-a, AR, BTC, EPR and HB-EGF, with EGFR, and therefore can be used in treating various diseases resulting from an activation of EGFR caused by binding not only with EGF but also with other EGFR ligands.

Abstract: Provided are antibodies specifically binding to the epidermal growth factor receptor (EGFR) which are effective for the treatment of EGFR-mediated cancers.

Abstract: A surgical instrument includes an extension portion having a surgical tool at an end thereof, and a head portion connected to the extension portion and actuating the surgical tool. In the surgical instrument, the extension portion includes a first extension portion connected to the head portion, a second extension portion having an elbow joint portion that is bending-actuated by a rigid rod that is reciprocated in a lengthwise direction by the head portion, and a connection portion connecting the first and second extension portions at an angle.

Abstract: A tire pressure monitoring system (TPMS) is provided. The TPMS includes: a plurality of sensors which output sensing signals, the plurality of sensors including a printable pressure sensor which senses an air pressure of a tire, and a temperature sensor which senses an air temperature inside the tire; a signal processor which is configured to process the sensing signals output by the plurality of sensors; a wireless power receiver which is configured to receive energy from a power source and output power; and a rechargeable battery which is configured to be charged by the power output by the wireless receiver and supply power to the plurality of sensors to sense the air pressure of the tire and the air temperature inside the tire.

Abstract: A method and apparatus for analyzing elastography of tissue using ultrasound waves, wherein elastography information of tissue in a region of interest (ROI) is analyzed by irradiating ultrasound waves for diagnosis towards the ROI to which a shear wave is induced from an ultrasound probe, receiving echo ultrasound waves, and acquiring three-dimensional (3D) ultrasound images with respect to the ROI.

Abstract: An endoscope includes a first lens unit that collects light corresponding to an object image which is an image including depth information of an object; a second lens unit that collects light corresponding to a surrounding tissue image which is an image of a surrounding tissue of the object; a switching unit that alternately applies light received from the first lens unit and the second lens unit to a photographing unit; and a photographing unit that alternately captures the light from the switching unit.

Abstract: A surgical implement and a manipulation system including the surgical implement may include at least one instrument including at least one joint portion. The joint portion may include a first part, a second part connected to the first part, and a force applying element for applying a force for bending (or rotating) the second part. A distance between a joint point and a force application point where a force is applied may be greater than a diameter of at least one of the first part and the second part. The instrument may further include a second joint portion spaced apart from the joint portion, and a surgical tool connected to an end portion of the second joint portion. The manipulation system may include a supporting structure, at least one instrument supported by the supporting structure, and an operating device for operating the instrument.

Abstract: A supporter device supports an instrument which is inserted in an object. The supporter device includes a base member having an insertion region through which the instrument passes, a movable member installed on the base member so as to move around the insertion region, and a pivot member installed to be pivotable based on a pivot axis that passes through the insertion region, wherein the instrument may be mounted on the pivot member. A movable central axis of the movable member and an extension axis of the instrument may cross at a single crossed point.

Abstract: An endoscope system and an endoscope includes a patterned light providing unit to provide patterned light having a pattern corresponding to a feature point; first and second capturing units to capture an object onto which the patterned light is irradiated; and a light transmitting unit to transmit the patterned light to the object and transmit light reflected by the object to the first and second capturing units.

Abstract: An apparatus and method of detecting bio molecular by measuring a variation of an electrical characteristic of a circuit having an inductance device and a capacitance device. The bio molecular detection method comprises providing a signal converting unit having at least one inductance device and at least one capacitance device connected with each other, disposing a biochip, which has capturing probe biomolecules attached to a substrate, at a location in the signal converting unit, and measuring an electrical characteristic of the signal converting unit, performing a coupling reaction of the biochip and a sample to be analyzed; and measuring an electrical characteristic of the signal converting unit after the coupling reaction.