Patents by Inventor Jong Keun Jeong

Jong Keun Jeong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis B virus vectors for gene therapy
    Patent number: 7001760
    Abstract: The present invention relates to novel hepatitis B virus vectors for use in gene therapy which can deliver therapeutic genes to liver cells. The invention also provides methods for the production of novel recombinant hepatitis B viruses. The recombinant viruses produced by this invention can deliver therapeutic genes specifically to liver cells either through in vivo or ex vivo therapy protocols. This vector can be used not only to treat liver diseases but also genetic diseases.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: February 21, 2006
    Inventors: Wang-Shick Ryu, Jehan Lee, Jong Keun Jeong, Woo Young Cho, Gye Soon Yoon
  • Humanized antibodies LB-00503 and LB-00506 specific for human 4-1BB and pharmaceutical compositions comprising said humanized antibodies
    Publication number: 20030096976
    Abstract: The present invention relates to humanized monoclonal antibodies LB-00503 and LB-00506, which are specific for human 4-1BB molecules, have high binding affinities and can bind efficiently with activated T cells expressing the 4-1BB molecule, as well as pharmaceutical compositions. Particularly, the present invention provides said humanized antibody LB-00503, which is modified from the humanized antibody Hz4B4-2 and substitutes the 61st amino acid, serine by asparagine in the amino acid residues of 59th˜61st and said humanized antibody LB-00506, which enhances the antibody binding affinity of said humanized antibody LB-00503 in which 2 amino acid residues of the right border in the antibody binding site CDR2 of the heavy chain variable region are substituted from glutamine (Q)—glycine (G) to lysine (K)—serine (S).
    Type: Application
    Filed: September 4, 2002
    Publication date: May 22, 2003
    Inventors: Hyo Jeong Hong, Sung Sup Park, Young Jun Kang, Chang-Yuil Kang, Sung Kwan Yoon, Youngwoo Park, Hyesung Yoon, Hyunsook Jang, Geun Bae Rha, Jin-San Yoo, Jong Keun Jeong, Dong Sup Shim, Mijeong Park, Hwadong Kim, Jung-Gyu Park, Jae-Young Yang
  • Hepatitis B virus vectors for gene therapy
    Publication number: 20010049145
    Abstract: The present invention relates to novel hepatitis B virus vectors for use in gene therapy which can deliver therapeutic genes to liver cells. The invention also provides methods for the production of novel recombinant hepatitis B viruses. The recombinant viruses produced by this invention can deliver therapeutic genes specifically to liver cells either through in vivo or ex vivo therapy protocols. This vector can be used not only to treat liver diseases but also genetic diseases.
    Type: Application
    Filed: April 19, 2001
    Publication date: December 6, 2001
    Inventors: Wang-Shick Ryu, Jehan Lee, Jong Keun Jeong, Woo Young Cho, Gye Soon Yoon