Abstract: The present invention relates to a stable pharmaceutical composition comprising omeprazole, its enantiomer, or its pharmaceutically acceptable salt, and sodium bicarbonate. Specifically, the present invention relates to a pharmaceutical composition with improved stability comprising a low dose of sodium bicarbonate, so that it has improved dissolution rate and bioavailability and also reduces side effects resulting from a high dose of sodium bicarbonate.

Abstract: The present invention relates to a stable pharmaceutical formulation comprising omeprazole, its enantiomer, or its pharmaceutically acceptable salt, and sodium bicarbonate, and a method for preparing the same. Specifically, the present invention provides a stable formulation by preventing omeprazole, its enantiomer, or its pharmaceutically acceptable salt, from coming in direct contact with sodium bicarbonate, to reduce the production of impurities.

Abstract: The present invention relates to a pharmaceutical preparation comprising omeprazole, an enantiomer thereof or a pharmaceutically acceptable salt thereof, and sodium bicarbonate, and a method for preparing the same. Specifically, the present invention relates to a pharmaceutical preparation, wherein a first mixed part comprising esomeprazole comprises 40% by weight or less of sodium bicarbonate based on the total weight of sodium bicarbonate comprised in the preparation, and thus sodium bicarbonate is first dissolved so as to raise pH, and then esomeprazole is dissolved such that the release properties of an active ingredient are improved, and thus the dissolution pattern and bioavailability of a drug can be enhanced.

Abstract: The present invention relates to a stable pharmaceutical composition comprising an omeprazole, an enantiomer thereof or a pharmaceutically acceptable salt thereof, and sodium bicarbonate. Specifically, the present invention relates to a pharmaceutical composition having improved stability, which includes a low content of sodium bicarbonate and has excellent dissolution rate and bioavailability and a reduced side effect due to a high content of sodium bicarbonate.

Abstract: The present invention relates to a pharmaceutical preparation comprising omeprazole, an enantiomer thereof or a pharmaceutically acceptable salt thereof, and sodium bicarbonate, and a method for preparing the same. Specifically, the present invention relates to a pharmaceutical preparation in which sodium bicarbonate is first disintegrated so as to raise pH, and then omeprazole is dissolved such that the release properties of an active ingredient are improved, and thus the dissolution pattern and bioavailability of a drug can be enhanced.

Abstract: The present invention relates to a stable pharmaceutical formulation comprising omeprazole, its enantiomer, or its pharmaceutically acceptable salt, and sodium bicarbonate, and a method for preparing the same. Specifically, the present invention provides a stable formulation by preventing omeprazole, its enantiomer, or its pharmaceutically acceptable salt, from coming in direct contact with sodium bicarbonate, to reduce the production of impurities.

Abstract: The present invention relates to a stable pharmaceutical composition comprising omeprazole, its enantiomer, or its pharmaceutically acceptable salt, and sodium bicarbonate. Specifically, the present invention relates to a pharmaceutical composition with improved stability comprising a low dose of sodium bicarbonate, so that it has improved dissolution rate and bioavailability and also reduces side effects resulting from a high dose of sodium bicarbonate.

Abstract: A positive active material for a rechargeable lithium battery including a core including at least one selected from a nickel-based composite oxide represented by Chemical Formula 1 or a lithium manganese oxide represented by Chemical Formula 2; and a coating layer on a surface of the core and including a lithium metal oxide represented by Chemical Formula 3, the positive active material having a peak at a 2? value of about 19° to about 22° and another peak at a 2? value of about 40° to about 45° in an X-ray diffraction pattern using a CuK? ray, is disclosed. A method of preparing the same, and a rechargeable lithium battery including the same, are also disclosed. LiNixCoyMn1-x-yO2??Chemical Formula 1 LiaMnbOc??Chemical Formula 2 Li2MO3??Chemical Formula 3 In Chemical Formulae 1 to 3, x, y, a, b, c, and M are the same as in the detailed description.

Abstract: An electron collector structure and a lithium battery including the same are disclosed. The electron collector structure includes a conductive thin film; and a graphene layer that is coated on the surface of the conductive thin film and may improve the electrical conductivity of an electrode plate. As an electrode of the lithium battery includes the electron collector structure, the electrical conductivity of the electrode may be increased so that the energy consumption properties as well as the lifespan characteristics of the lithium battery may be also improved.

Abstract: A positive active material for a rechargeable lithium battery includes a positive active material compound including a metal compound for intercalating and deintercalating lithium, a coating particle having an embedded portion embedded into the active material compound and a protruding portion protruding from the surface of the active material, and a rechargeable lithium battery including the positive active material.

Abstract: An electrode active material for a lithium secondary battery, a method of preparing the electrode active material, an electrode for a lithium secondary battery which includes the same, a lithium secondary battery using the electrode. The electrode active material includes a core active material and a coating layer including magnesium aluminum oxide (MgAlO2) and formed on the core active material. 1s binding energy peaks of oxygen (O) in the electrode active material measured by x-ray photoelectron spectroscopy (XPS) are shown at positions corresponding to 529.4±0.5 eV, about 530.7 eV, and 531.9±0.5 eV, and a peak intensity at the position corresponding to 529.4±0.5 eV is stronger than a peak intensity at the position corresponding to about 530.7 eV.

Abstract: A positive active material for a rechargeable lithium battery includes a lithium composite metal oxide represented by Chemical Formula 1. A method of preparing the positive active material includes adding a lithium metal oxide represented by Chemical Formula 2 to a Zr salt-containing solution to obtain a mixed solution, drying the mixed solution to obtain a dried product, and heat-treating the dried product to prepare a lithium composite metal oxide represented by Chemical Formula 1. A rechargeable lithium battery includes a positive electrode including the positive active material. LiaZrbNicCodMeZrfO2??[Chemical Formula 1] where, 0.9?a?1.1, 0<b?0.1, 0?c?1, 0?d?1, 0?e?1, 0?f?0.1, 0.9?a+b?1.1, c+d+e+f=1, and M is Mn or Al, LiaNigCohMiO2??[Chemical Formula 2] where, 0.9?a?1.1, 0?g?1, 0?h?1, 0?i?1, g+h+i=1 and M is Mn or Al.

Abstract: An electrode for a lithium secondary battery includes a silicon-based alloy, and has a surface roughness of about 1 to about 10 ?m and a surface roughness deviation of 5 ?m or less. A method of manufacturing the electrode includes mixing an electrode composition, milling the composition, coating the milled composition on a current collector, and drying the milled composition. A lithium secondary battery includes the electrode.

Abstract: Disclosed is a solid electrolyte including particles comprising Li(1+x)Ti(2-x)Alx(PO4)3 (0?x?1) having a true density of about 2.20 to about 2.50 g/cm3.

Abstract: A negative active material for a rechargeable lithium battery includes a Si—Al—Fe alloy represented by Formula 1. The Si—Al—Fe alloy includes a Si phase and an alloy phase, and the alloy phase includes Si, Al, and Fe in a ratio of atomic percentages of about 3:3:2: xSi-yAl-zFe??Formula 1 wherein 50 at %?x?90 at %, 5 at %?y?30 at %, 5 at %?z?30 at %, and x+y+z=100 at %.

Abstract: A positive active material for a rechargeable lithium battery includes a nickel-based composite oxide represented by the following Chemical Formula 1, wherein the nickel-based composite oxide includes an over lithiated oxide and non-continuous portions of a lithium nickel cobalt manganese oxide on a surface of the over lithiated oxide. LiaNibCocMndO2??Chemical Formula 1 where 1<a<1.6, 0.1<b<0.7, 0.1<c<0.4, and 0.1<d<0.7.

Abstract: A positive active material for a rechargeable lithium battery, a method of manufacturing the same, and a rechargeable lithium battery using the same, the positive active material including a secondary particle formed of a plurality of primary particles, the primary particles being made of a metal compound capable of intercalating/deintercalating lithium; and a coating layer on a surface of the secondary particle in an island arrangement, the coating layer including a metal oxide, wherein the secondary particle includes pores formed by the primary particles, the pores including a surface pore on the surface of the secondary particle and an internal pore inside the secondary particle, and the metal oxide of the coating layer fills a portion of the surface pore of the secondary particle.

Abstract: A negative active material for a lithium battery with an improved cycle characteristic and capacity retention rate, and the negative active material comprises a plurality of particles comprising a plurality of first particles comprising Si, Ti, and Ni; and composite particles comprising a plurality of second particles in which at least one element selected from the group consisting of Cu, Fe, Ni, Au, Ag, Pd, Cr, Mn, Ti, B, and P is partially or completely deposited on surface(s) of other of first particles, a method of preparing the negative active material, and a lithium battery including a negative electrode including the negative active material.

Abstract: Disclosed is a rechargeable lithium battery including: a positive electrode; a negative electrode including a negative current collector including a copper foil having elongation of about 5% to about 10% and a particle size of about 1 ?m to about 20 ?m, and a negative active material layer provided on the negative current collector; and an electrolyte solution.

Abstract: A negative active material having controlled particle size distribution of silicon nanoparticles in a silicon-based alloy, a lithium battery including the negative active material, and a method of manufacturing the negative active material are disclosed. The negative active material may improve capacity and lifespan characteristics by inhibiting (or reducing) volumetric expansion of the silicon-based alloy. The negative active material may include a silicon-based alloy including: a silicon alloy-based matrix; and silicon nanoparticles distributed in the silicon alloy-based matrix, wherein a particle size distribution of the silicon nanoparticles satisfies D10?10 nm and D90?75 nm.