Abstract: The present invention relates to a polypeptide improved in protein purity and in affinity for a target antigen, a conjugate thereof with an antibody or antigen-binding fragment, and a preparation method of the polypeptide and the conjugate. The polypeptide or the conjugate thereof according to the present invention does not undergo glycosylation even when produced in a eukaryotic cell and thus has high protein purity and affinity for a target antigen, showing a very high value as a reagent for diagnosis or treatment of a disease.

Abstract: An information handling system organic light emitting diode (OLED) display adapts presentation of visual information to manage a display thermal state, such as to maintain a uniform thermal condition. In one example embodiment, a first display zone of plural pixels presents visual images with a first refresh rate, such as the nominal refresh rate established by the display settings, and a second display zone presents visual images with a partial pixel refresh rate that reduces power dissipation and, thus, thermal energy release so that a more uniform thermal state may be achieved at the display.

Abstract: A display device including a display panel, a plurality of gripping sensors at a side of the display device and configured to detect a gripping of the side of the display device, and a plurality of touch sensors on the display panel and configured to generate a sensing output signal based on sensing input signals, in which the sensing input signals having different enable voltages are applied to the plurality of touch sensors, and the different enable voltages are determined according to the gripping.

Abstract: Disclosed is a display module including a transparent display panel and a frame to fix a side of the transparent display panel, wherein the frame has a communication unit to receive data from the outside, a controller to process the received data and to output a drive command corresponding to the processed data and a display drive unit to drive the transparent display panel in response to the drive command from the controller. A display system includes a system body and a display module detachably mounted in the system body.

Abstract: Disclosed are a novel antibody specifically binding to the tumor-immunosuppressant, TIGIT (T cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif [ITIM] domain) or an antigen-binding fragment thereof, a nucleic acid encoding the antibody or the antigen-binding fragment thereof, a vector and a host cell including the nucleic acid, a method for producing the antibody or the antigen-binding fragment thereof, a pharmaceutical composition containing the antibody or the antigen-binding fragment thereof as an active ingredient, and uses of the pharmaceutical composition. The antibody specifically binding to TIGIT or the antigen-binding fragment thereof and the pharmaceutical composition containing the same as an active ingredient are preferably used for the treatment of cancer or tumors.

Abstract: An exemplary embodiment of the present inventive concept provides a display device including: a display unit including a plurality of pixels disposed on a display area; a display controller configured to control the display unit; a sensor including a plurality of first sensing electrodes and a plurality of second sensing electrodes disposed in the display area; and a sensor controller configured to recognize a touch of a user inputted into the sensor in a touch sensing mode and to recognize a fingerprint of the user inputted into the sensor in a fingerprint sensing mode, wherein the sensor controller changes a mode to the fingerprint sensing mode when no touch is inputted for a predetermined time period in the touch sensing mode and changes the mode to the touch sensing mode when authorization on a fingerprint inputted into the sensor is succeeded in the fingerprint sensing mode.

Abstract: The present invention relates to: a novel antibody or an antigen-binding fragment thereof for use in the treatment of cancer by targeting B cell malignancies; a chimeric antigen receptor comprising the same; and uses thereof. The antibody of the present invention is an antibody specifically binding to CD19 highly expressed in cancer cells (particularly, blood cancer) and has very low homology compared to the CDR sequences of conventional CD19 target antibodies, and thus the sequence thereof is unique. In addition, cells expressing a chimeric antigen receptor comprising an anti-CD19 antibody or antigen-binding fragment of the present invention induce immune cell activity in response to a positive cell line expressing CD19, and thus can be usefully used as a therapeutic agent for CAR-immune cells.

Abstract: The present disclosure relates to a novel anti-HER2 antibody or an antigen-binding fragment thereof used in the prevention or treatment of cancer, a chimeric antigen receptor including the same, and uses thereof. The antibody of the present disclosure is an antibody that specifically binds to HER2 which is highly expressed in cancer cells (particularly, breast cancer or gastric cancer cells), and binds to an epitope that is different from an epitope to which trastuzumab binds.

Abstract: The present invention relates to a new antibody or an antigen binding fragment thereof for use in the treatment of cancer by targeting a B cell malignancy, a chimeric antigen receptor comprising the same, and a use of the same. The antibody of the present invention is an antibody for specifically binding to CD19 that is highly expressed in cancer cells (particularly, blood cancer), has very low homology to a CDR sequence thereof compared to a CDR sequence of a conventional CD19 target antibody so that the sequence thereof is unique, and specifically binds to an epitope that is different from a FMC63 antibody fragment binding to CD19 of the conventional art. A cell expressing the chimeric antigen receptor comprising an anti-CD19 antibody or the antigen binding fragment of the present invention induces immune cell activity in response to a positive cell line expressing CD19.

Abstract: An environmental sensor for an electronic device includes a substrate, a first sensing unit having a first sensor electrode disposed on the substrate, a second sensing unit having a second sensor electrode disposed on the substrate, an insulating layer covering the first sensor electrode, and a cover that is disposed over the first and second sensor electrodes, the cover including at least one hole through which chemical particles pass. The first and second sensing units each sense one of a capacitance-change due to the chemical particles that pass through the hole and then adhere to the insulating layer located on the first sensor electrode and a resistance-change due to the chemical particles that pass through the hole and then adhere to the second sensor electrode.

Abstract: A display device includes: a display panel configured to display an image; a sound element on a rear side of the display panel; and a rear chassis configured to receive the display panel and protect the rear side of the display panel, and including a protruding portion protruding away from the rear side of the display panel and corresponding to the sound element. The sound element includes a pair of electrodes, and a vibration material layer between the electrodes.

Abstract: A display device includes: a display panel configured to display an image; a sound element on a rear side of the display panel; and a rear chassis configured to receive the display panel and protect the rear side of the display panel, and including a protruding portion protruding away from the rear side of the display panel and corresponding to the sound element. The sound element includes a pair of electrodes, and a vibration material layer between the electrodes.

Abstract: A head mounted display device includes: display part disposed to correspond to two eyes of a user, and including wires and one or more pixels connected to the wires; and a sensor disposed around the display part and configured to sense a touch of the user. The sensor includes sensing electrodes, and at least one of the sensing electrodes is provided on the same layer as a portion of the display part.

Abstract: Disclosed is a display module including a transparent display panel and a frame to fix a side of the transparent display panel, wherein the frame has a communication unit to receive data from the outside, a controller to process the received data and to output a drive command corresponding to the processed data and a display drive unit to drive the transparent display panel in response to the drive command from the controller. A display system includes a system body and a display module detachably mounted in the system body.

Abstract: An apparatus for user authentication includes a sensor array and a sensing signal processor. The sensor array is formed on at least one surface of a mobile device. The sensing signal processor receives information of a palm of a user, received from the sensor array, and performs a user authentication through pattern analysis. Accordingly, an authentication of the user of the mobile device can be simply performed.

Abstract: The present invention provides a pneumatic tire including a tread block 10 having a sipe 100 formed therein. A three-dimensional inclined surface groove 110 is formed at an upper portion of the sipe 100 formed in the tread block 10, such that three-dimensional inclined surface protrusions 16 and inclined surface grooves 17 respectively formed on both sipe side wall surfaces 15 forming the sipe 100 so as to correspond to each other may minimize a movement of the tread blocks 10 due to a stress generated from the tire contacting with a ground during driving, so as to increase a traction force.

Abstract: Provided is an electric device including: a main body comprising a storage chamber with an opening; a door coupled to the main body and comprising a transparent display panel such that the transparent display panel covers at least a part of the opening when the door is closed; a movement detector being configured to detect a movement of the transparent display panel and output a movement detection signal corresponding to the movement; and a controller configured to identify a position of the transparent display panel based on the movement detection signal, and control the transparent display panel to reverse an image displayed on the transparent display panel based on the identified position of the transparent display panel being changed from a first position to a second position.

Abstract: A display device including a display panel, a plurality of gripping sensors at a side of the display device and configured to detect a gripping of the side of the display device, and a plurality of touch sensors on the display panel and configured to generate a sensing output signal based on sensing input signals, in which the sensing input signals having different enable voltages are applied to the plurality of touch sensors, and the different enable voltages are determined according to the gripping.

Abstract: An exemplary embodiment of the present inventive concept provides a display device including: a display unit including a plurality of pixels disposed on a display area; a display controller configured to control the display unit; a sensor including a plurality of first sensing electrodes and a plurality of second sensing electrodes disposed in the display area; and a sensor controller configured to recognize a touch of a user inputted into the sensor in a touch sensing mode and to recognize a fingerprint of the user inputted into the sensor in a fingerprint sensing mode, wherein the sensor controller changes a mode to the fingerprint sensing mode when no touch is inputted for a predetermined time period in the touch sensing mode and changes the mode to the touch sensing mode when authorization on a fingerprint inputted into the sensor is succeeded in the fingerprint sensing mode.

Abstract: A display device unit includes: a display device; and a sound element disposed at a side surface or a rear surface of the display device, where the sound element includes a vibration material layer which provides a sound based on an electric field applied therein, and a pair of electrodes which generates the electric field in the vibration material layer.