Abstract: Provided are a compound having an inhibitory activity against glucosylceramide synthase (GCS), i.e., compounds having a 2,3-dihydro-1H-indene, 1,2,3,4-tetrahydronaphthalene, or chromane moiety, or pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof, wherein the compound or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and exhibits the effects of alleviating symptoms in the central nervous system as well as in the peripheral nervous system, through excellent blood-brain barrier permeability, and therefore, the compound or pharmaceutically acceptable salt thereof can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.

Abstract: Provided are a compound having a cyclohexyl-(alkyl or cycloalkyl-substituted)ethylene-amino-heteroaryl moiety or pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof, wherein the compound or pharmaceutically acceptable salt thereof not only has excellent inhibitory activity against indoleamine 2,3-dioxygenase (IDO) but also exhibits remarkably high in vivo exposure upon oral administration and therefore the compound or pharmaceutically acceptable salt thereof can be usefully applied for preventing or treating various diseases associated with IDO.

Abstract: An energy storage device includes positive and negative electrodes; positive and negative lead wires connected to the positive and negative electrodes, respectively; a separator composed of unit fibers and positioned between the positive and negative electrodes to electrically insulate the positive and negative electrodes from each other; a housing accommodating the positive and negative electrodes and the separator; an electrolyte received in the housing; and positive and negative terminals connected to the positive and negative lead wires, respectively, wherein an electrolyte permeability index of the separator is larger than an electrolyte permeability index of the electrodes, and the unit fibers of the separator are arranged irregularly so that pores formed in the separator have cross sections of polygonal shapes. Using this energy storage device, the electrolyte of electrodes that gives a direct influence on electric capacity is not depleted.

Abstract: Disclosed is an energy storage device, in which an electrode material including an aqueous solvent, a binder and a transition metal oxide containing lithium is used to form one electrode, and an electrode material including activated carbon is used to form the other electrode. In particular, the energy storage device ensures reliability and maximum capacitance efficiency by optimizing density and thickness values of the electrode materials for the cathode electrode and the anode electrode.

Abstract: An energy storage device includes positive and negative electrodes; positive and negative lead wires connected to the positive and negative electrodes, respectively; a separator composed of unit fibers and positioned between the positive and negative electrodes to electrically insulate the positive and negative electrodes from each other; a housing accommodating the positive and negative electrodes and the separator; an electrolyte received in the housing; and positive and negative terminals connected to the positive and negative lead wires, respectively, wherein an electrolyte permeability index of the separator is larger than an electrolyte permeability index of the electrodes, and the unit fibers of the separator are arranged irregularly so that pores formed in the separator have cross sections of polygonal shapes. Using this energy storage device, the electrolyte of electrodes that gives a direct influence on electric capacity is not depleted.

Abstract: A chuck assembly for high density plasma equipment includes: a chuck having an upper surface and a plurality of pin holes formed in an outer peripheral portion, wherein the chuck upper surface is configured to receive a semiconductor substrate thereon; a substrate guide disposed on an outer surface of the chuck, wherein the substrate guide is configured to prevent a semiconductor substrate positioned on the upper surface of the chuck from being separated from the chuck; a fixing plate disposed at a lower portion of the chuck; a plurality of lift pins secured to the fixing plate and extending in an upward direction from the fixing plate so that each lift pin is inserted into a respective one of the pin holes, wherein each lift pin has an upper surface that extends to a position adjacent to the upper surface of the chuck; and a chuck lifter penetrating the fixing plate and engaged with a lower portion of the chuck, wherein the chuck lifter is configured to move the chuck upward and downward.

Abstract: The present invention discloses a stepped signal generating circuit for producing stepped signals having nearly perfect sinusoidal stepped signals. The stepped signal generating circuit comprises a plurality of current mirror switching sections, each having a P type and an N type current mirror for outputting constant currents upon receiving digital signals. N-MOS transistors are provided to pass or block the output current of each switching section. The constant currents outputted from the switching sections are then controlled by a constant voltage of the constant voltage source. The final output is controlled by a constant current of a constant current source before being outputted. Accordingly, the present invention generates precise and nearly sinusoidal stepped signals.