Patents by Inventor Jongkyeong Chung

Jongkyeong Chung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120088731
    Abstract: The present invention provides a method for curing Parkinson's disease through regulating VDAC1 (voltage-dependent anion channel 1) protein. Specifically, the present invention provides a pharmaceutical composition for curing PD comprising a VDAC1 protein regulator. The VDAC1 protein regulators comprise an inhibitor of VDAC1 mRNA production, an inhibitor of mitochondrial permeability transition pore (mPTP) formation, and a mitochondrial calcium uptake inhibitor. In addition, the present invention provides a method for curing Parkinson's disease comprising administering a VDAC1 protein regulator to a subject with Parkinson's disease. The present invention could provide a method for curing Parkinson's disease through preventing and/or restoring mitochondrial dysfunction.
    Type: Application
    Filed: October 14, 2010
    Publication date: April 12, 2012
    Applicant: SNU R&DB FOUNDATION
    Inventors: Jongkyeong Chung, Yongsung Kim
  • Publication number: 20090042810
    Abstract: The invention provides transgenic Drosophila embryos comprising in the germ cells an adenosine monophosphate-activated protein kinase (AMPK) null mutation. The transgenic Drosophila embryos are useful in screening drug candidates for treatment of a disease, such as cancer, kidney disease, diabetes, intestinal disease, and obesity. The invention further provides methods for detecting disease in a tissue, comprising detecting a change in AMPK activity in the tissue compared to a control tissue. Also provided are methods for reducing symptoms of a disease in a subject, comprising administering a therapeutic amount of a drug that changes AMPK activity to the subject.
    Type: Application
    Filed: April 22, 2008
    Publication date: February 12, 2009
    Inventor: Jongkyeong Chung
  • Patent number: 6943278
    Abstract: The present invention relates to animal models for neuronal function, e.g., spontaneous changes in motor ability related to neuronal degeneration. For example, the present invention provides a Drosophila melanogaster model for Parkinson's disease. The present invention also provides methods for generating genetically based neuronal disease models, identifying genes that affect neuronal function and methods for identifying compounds having activity with respect to neurological function.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: September 13, 2005
    Assignee: GenExel, Inc.
    Inventor: Jongkyeong Chung
  • Publication number: 20040073955
    Abstract: The present invention relates to animal models for neuronal function, e.g., spontaneous changes in motor ability related to neuronal degeneration. For example, the present invention provides a Drosophila melanogaster model for Parkinson's disease. The present invention also provides methods for generating genetically based neuronal disease models, identifying genes that affect neuronal function and methods for identifying compounds having activity with respect to neurological function.
    Type: Application
    Filed: October 15, 2002
    Publication date: April 15, 2004
    Inventor: Jongkyeong Chung