Patents by Inventor Jong-Ryul Ha

Jong-Ryul Ha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fab FRAGMENT SPECIFICALLY BINDING TO EGFR
    Publication number: 20170145101
    Abstract: The present invention relates to a fragment antigen-binding (Fab) fragment specifically binding to epidermal growth factor receptor (EGFR), an expression construct for preparing the Fab fragment, a method for preparing the Fab fragment, and a pharmaceutical composition containing the Fab fragment. The Fab fragment to EGFR of the present invention is smaller than the antibody, and thus can favorably permeate into tissues or tumors and can be prepared in bacteria, resulting in low production costs. Furthermore, the Fab fragment to EGFR of the present invention has an increased in vivo half-life through pegylation.
    Type: Application
    Filed: December 7, 2015
    Publication date: May 25, 2017
    Inventors: Young Pil KIM, Hye Rim KIM, Hee Jung YOO, Seong Hwan LEE, Tai Geun JUNG, Jong Ryul HA
  • Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases
    Patent number: 6693126
    Abstract: The present invention relates to a pharmaceutical composition for the hepatoprotection and treatment of liver diseases comprising as an active ingredient a dihydroxyphenyl derivative represented by the following formula (1), pharmaceutically acceptable acid addition salt or stereochemical isomer thereof together with a pharmaceutically acceptable inert carrier: in which in which A, B, D and E are defined as described in the specification.
    Type: Grant
    Filed: April 1, 2002
    Date of Patent: February 17, 2004
    Assignee: Choongwae Pharm. Co., Ltd.
    Inventors: Sung-Hwan Moon, Hea-Jin Choi, Su-Jin Lee, Jea-Uk Chung, Jong-Ryul Ha, Kwang-Won Jeong, Se-Woong Oh
  • Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases
    Publication number: 20030083326
    Abstract: The present invention relates to a pharmaceutical composition for the hepatoprotection and treatment of liver diseases comprising as an active ingredient a dihydroxyphenyl derivative represented by the following formula (1), pharmaceutically acceptable acid addition salt or stereochemical isomer thereof together with a pharmaceutically acceptable inert carrier: 1
    Type: Application
    Filed: April 1, 2002
    Publication date: May 1, 2003
    Applicant: Choongwae Pharm. Co., Ltd.
    Inventors: Sung-Hwan Moon, Hea-Jin Choi, Su-Jin Lee, Jea-Uk Chung, Jong-Ryul Ha, Kwang-Won Jeong, Se-Woong Oh
  • Genipin derivative having liver protection activity
    Patent number: 6262083
    Abstract: The present invention relates to novel genipin derivatives which have an excellent liver protection activity with little cytotoxicity, and these compounds are so stable in vivo that they do not induce any side effects.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: July 17, 2001
    Assignee: Choongwae Pharma Corporation
    Inventors: Sung-Hwan Moon, Hea-Jin Choi, Su-Jin Lee, Jea-Uk Chung, Jong-Ryul Ha, Kyoung-June Lee, Se-Woong Oh, Kwang-Won Jeong