Patents by Inventor Joo Kyung Lee

Joo Kyung Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microorganism streptomyces exfoliatus yj-118 and a method for producing pravastatin sodium by using the strain
    Patent number: 6306629
    Abstract: The present invention is related to a new microorganism Streptomyces exfoliatus YJ-118 and a method for producing pravastatin sodium by using this microorganism which shows a strong tolerance to ML-236B and a high hydroxylation activity of ML-236B to pravastatin.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: October 23, 2001
    Assignee: Yungjin Pharmaceutical Ind. Co., Ltd.
    Inventors: Joo-Kyung Lee, Joo-Woong Park, Dong-Jin Seo, Sang-Choon Lee, Ji-Yoon Kim
  • Method for producing pravastatin precursor, ML-236B
    Patent number: 6204032
    Abstract: The present invention is related to a new method for producing ML-236B, a precursor of pravastatin sodium, in particular to a method for producing ML-236B lactone form(I), free acid form(II), sodium salt(III) shown in the formulae (I), (II), (III) by using a new microorganism isolated from soil. ML-236B is obtained from the culture broth of this microorganism and it is used as a substrate of pravastatin sodium which is a potent cholesterol-lowering agent used in treatment for hypercholesterolemia.
    Type: Grant
    Filed: December 29, 1998
    Date of Patent: March 20, 2001
    Assignee: Yungjin Pharameutical Ind. Co., Ltd.
    Inventors: Kae Jong Chung, Joo Kyung Lee, Joo Woong Park, Dong Jin Seo, Sang Choon Lee