Abstract: A needleless syringe having a multi-nozzle and a manufacturing method therefor are proposed. The needleless syringe injects a drug solution through an injection nozzle by expanding a pressure-generating liquid by means of energy generated from a pressure-generating unit, wherein precise branch channels are stably formed so as to inject drugs into a plurality of parts by using multiple injection nozzles. Further, the present disclosure has advantages in that: one energy-generating unit is used and thus nozzles can be densely arranged with a small distance therebetween; when several injections into an affected part are needed, the treatment time can be shortened using multiple injection nozzles; and an inner chamber is inserted into and coupled to or is insert injection-molded in an outer chamber so that more stable and precise branch channels can be formed, and thus multiple drugs can be stably injected into an affected part through multiple injection nozzles.