Abstract: The subject invention provides oligo(carbamoylated guanidine)s (OCGs) having fast and selective mycobactericidal effects via disruption of the mycobacterial membrane potential. OCGs also potentiates bedaquiline, an oxidative phosphorylation-targeting anti-TB drug. The combination of OCG and anti-TB drug can be used as an effective therapy for treating tuberculosis.

Abstract: A cell-penetrating peptide (CPP) comprising a plurality of mono(amino acid)s, oligo(amino acid)s, or poly(amino acid)s where a plurality of the amino acids comprise a positively charged guanylurea unit with a small molecule fragment and each of the mono(amino acid)s, oligo(amino acid)s, or poly(amino acid)s comprising a drug attached through a linker. The CPP can be used for treating cancers.

Abstract: The inventive concept provides a teaching method for teaching a transfer position of a transfer robot. The teaching method includes: searching for an object on which a target object to be transferred by the transfer robot is placed, based on a 3D position information acquired by a first sensor; and acquiring coordinates of a second direction and coordinates of a third direction of the object based on a data acquired from a second sensor which is a different type from the first sensor.

Abstract: The present disclosure relates to a clip apparatus for an endoscope, the clip apparatus having a simple driving part and enabling accurate and easy clip ligation and separation. The present disclosure provides a clip apparatus for an endoscope, the clip apparatus comprising: a handle part having a moving hole formed therein; a handle slider installed so as to be slidable in the handle part through the moving hole; an inner sheath rotatably connected to the inside of the handle part and extending to the outside of the handle part; a wire connected to the handle slider and disposed inside the inner sheath; an outer sheath disposed so as to cover the inner sheath; an outer handle coupled to the outer sheath so as to move the outer sheath along the length direction of the inner sheath; and a clip coupling part connected to one end of the wire and enabling the coupling of a clip.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery using a positive electrode containing the positive electrode active material. More particularly, the present invention relates to a positive electrode active material that is able to solve a problem of increased resistance according to an increase in Ni content by forming a charge transport channel in a lithium composite oxide and a lithium secondary battery using a positive electrode containing the positive electrode active material.

Abstract: A server according to an embodiment includes a processor configured to receive a friend add request for a target account from a user terminal accessed with a user account; based on one of the user account and the target account being a protected account, transmit an approval request for the friend add request to a protector account connected to the protected account; and based on receiving a reply to the approval request from the protector terminal, add the target account to a friend list of the user account.

Abstract: A hair dye dispenser according to an embodiment of the present invention includes a housing having an opening hole formed on one side of which a hair dye is provided, a plurality of cartridges disposed inside the housing and accommodating at least one dyeing material, a main body in which the plurality of cartridges are rotatably disposed, a main motor for rotating the main body so that a first cartridge of the plurality of cartridges is located adjacent to the opening hole, a discharge module for discharging the dyeing material contained in the first cartridge, and an accommodating body in which a basket accommodating the dyeing material discharged by the discharge module is placed, wherein the discharge module may include an elevating body that pressurizes the first cartridge when moving up and is separated from the first cartridge when moving down.

Abstract: The present invention relates to a positive electrode active material having improved electrical characteristics by adjusting an aspect ratio gradient of primary particles included in a secondary particle. a positive electrode including the positive electrode active material, and a lithium secondary battery using the positive electrode.

Abstract: The subject invention provides oligo(carbamoylated guanidine)s (OCGs) having fast and selective mycobactericidal effects via disruption of the mycobacterial membrane potential. OCGs also potentiates bedaquiline, an oxidative phosphorylation-targeting anti-TB drug. The combination of OCG and anti-TB drug can be used as an effective therapy for treating tuberculosis.

Abstract: The subject invention provides oligo(carbamoylated guanidine)s (OCGs) having fast and selective mycobactericidal effects via disruption of the mycobacterial membrane potential. OCGs also potentiates bedaquiline, an oxidative phosphorylation-targeting anti-TB drug. The combination of OCG and anti-TB drug can be used as an effective therapy for treating tuberculosis.

Abstract: The present invention relates to a positive electrode active material having improved electrical characteristics by adjusting an aspect ratio gradient of primary particles included in a secondary particle, a positive electrode including the positive electrode active material, and a lithium secondary battery using the positive electrode.

Abstract: A multi-chamber cartridge and a nucleic acid extraction module including the same are provided. The multi-chamber cartridge according to an aspect of the present invention may include a sample chamber including a first tube which is an elongated hollow type, a sample chamber body in which a mixing space is formed and one end of the first tube is disposed in the mixing space, a first pressure gasket which can be coupled to the inside of the first tube and is movable along the inner peripheral surface of the first tube, a first separation gasket which is disposed on one surface of the first pressure gasket, coupled to the inside of the first tube, and movable along the inner peripheral surface of the first tube, and a first plunger having one end coupled to the other surface of the first pressure gasket and pressing the first pressure gasket; and a cartridge body which includes an accommodating part in which the sample chamber is detachably accommodated.

Abstract: The subject invention provides materials and methods for intracellular deliver of molecules and/or therapeutic agents. The subject invention also provides methods for synthesizing polymeric systems and nanomaterials that enhance or assist the passage of molecules and/or therapeutic agents across biological membranes. The compound, polymer or nanoparticle of the subject invention comprises a modified guanidine moiety in a plurality of repeating units of a polymer or on the surface of a nanoparticle where the guanidine moiety comprises, for example, a carbamoyl or thiourea modification. The polymer or nanoparticle can be used in a cancer treatment formulation.

Abstract: A detection kit, a detection apparatus and a method for manufacturing a detection kit are provided. The detection kit according to an aspect of the present invention may include a plate-shaped detection member; a first photothermal area which is formed on one side of the detection member and fixes a photothermal material that generates heat exposed to light; and a first sample area which is disposed adjacent to the first photothermal area to receive heat from the first photothermal area when light is irradiated onto the first photothermal area.

Abstract: The subject invention provides materials and methods for intracellular deliver of molecules and/or therapeutic agents. The subject invention also provides methods for synthesizing polymeric systems and nanomaterials that enhance or assist the passage of molecules and/or therapeutic agents across biological membranes. The compound, polymer or nanoparticle of the subject invention comprises a modified guanidine moiety in a plurality of repeating units of a polymer or on the surface of a nanoparticle where the guanidine moiety comprises, for example, a carbamoyl or thiourea modification. The polymer or nanoparticle can be used in a cancer treatment formulation.

Abstract: A lithium complex oxide includes a mixture of first particles of n1 (n1>40) aggregated primary particles and second particles of n2 (n2?20) aggregated primary particles, the lithium complex oxide represented by Chemical Formula 1 and having FWHM (deg., 2?) of 104 peak in XRD, defined by a hexagonal lattice having R-3m space group, in a range of Formula 1: LiaNixCoyMnzM1-x-y-zO2, ??[Chemical Formula 1] where M is selected from: B, Ba, Ce, Cr, F, Mg, Al, Cr, V, Ti, Fe, Zr, Zn, Si, Y, Nb, Ga, Sn, Mo, W, P, Sr, and any combination thereof, 0.9?a?1.3, 0.6?x?1.0, 0.0?y?=0.4, 0.0?z?0.4, and 0.0?1-x-y-z?0.4, ?0.025?FWHM(104)?{0.04+(xfirst particle?0.6)×0.25}?0.025, ??[Formula 1] where FWHM(104) is represented by Formula 2, FWHM(104)={(FWHMChemical Formula 1 powder(104)?0.1×mass ratio of second particles)/mass ratio of first particles}?FWHMSi powder (220).

Abstract: Provided is a seismic vulnerability analysis system of a user's living space. The system includes: an image receiving unit configured to receive image information obtained by photographing a living space, where various things are disposed, through a camera; an image signal processing unit configured to recognize the thing photographed in the image information as an object, extract a position and size of the object in a three-dimensional space, and convert the extracted position and size into spatial information; and an earthquake simulation unit configured to simulate motion phenomena of the objects in the space when an earthquake occurs according to simulated seismic conditions based on the spatial information.

Abstract: The present invention relates to a positive electrode active material and a lithium secondary battery comprising the same, and more specifically, to a positive electrode active material including a lithium composite oxide containing at least nickel and titanium, wherein the titanium is present in an oxide form in at least a portion of the surface of the lithium composite oxide at the same time as being doped in the lithium composite oxide, and thus it is possible to simultaneously improve the output efficiency and high-temperature lifetime characteristics (high-temperature cycle capacity retention rate) of a lithium secondary battery using the positive electrode active material, and a lithium secondary battery including the same.

Abstract: A lithium complex oxide includes a mixture of first particles of n1 (n1>40) aggregated primary particles and second particles of n2 (n2?20) aggregated primary particles, the lithium complex oxide represented by Chemical Formula 1 and having FWHM (deg., 2?) of 104 peak in XRD, defined by a hexagonal lattice having R-3m space group, in a range of Formula 1: LiaNixCoyMnzM1-x-y-zO2,??[Chemical Formula 1] where M is selected from: B, Ba, Ce, Cr, F, Mg, Al, Cr, V, Ti, Fe, Zr, Zn, Si, Y, Nb, Ga, Sn, Mo, W, P, Sr, and any combination thereof, 0.9?a?1.3, 0.6?x?1.0, 0.0?y?=0.4, 0.0?z?0.4, and 0.0?1?x?y?z?0.4, ?0.025?FWHM(104)?{0.04+(xfirst particle?0.6)×0.25}?0.025,??[Formula 1] where FWHM(104) is represented by Formula 2, FWHM(104)={(FWHMChemical Formula 1 powder(104)?0.1×mass ratio of second particles)/mass ratio of first particles}?FWHMSi powder(220).

Abstract: The present invention relates to a positive electrode active material having improved electrical characteristics by adjusting an aspect ratio gradient of primary particles included in a secondary particle, a positive electrode including the positive electrode active material, and a lithium secondary battery using the positive electrode.