Patents by Inventor Jordan J. Toutounchian

Jordan J. Toutounchian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for regulating retinal endothelial cell viability
    Patent number: 10010516
    Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: July 3, 2018
    Assignee: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Jena Steinle Smith, Duane Douglas Miller, Jordan J. Toutounchian
  • Inhibitors of paxillin function and related compositions and methods
    Patent number: 9834525
    Abstract: This disclosure relates to small molecule inhibitors of paxillin and paxillin binding, and related compositions and methods of treatment.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: December 5, 2017
    Assignee: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Charles Ryan Yates, Duane D. Miller, Frank Park, Jordan J. Toutounchian, Vanessa Morales-Tirado, Shivaputra Patil, Jayaprakash Pagadala, Bilal Abou Aleiwi
  • Method for regulating retinal endothelial cell viability
    Patent number: 9566255
    Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: February 14, 2017
    Assignee: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Jena Steinle Smith, Duane Douglas Miller, Jordan J. Toutounchian
  • INHIBITORS OF PAXILLIN FUNCTION AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20160347725
    Abstract: This disclosure relates to small molecule inhibitors of paxillin and paxillin binding, and related compositions and methods of treatment.
    Type: Application
    Filed: February 4, 2015
    Publication date: December 1, 2016
    Inventors: Charles Ryan Yates, Duane D. Miller, Frank Park, Jordan J. Toutounchian, Vanessa Moraies-Tirado, Shivaputra Patil, Jayaprakash Pagadala, Bial Abou Aleiwi
  • Anti-inflammatory quinic acid derivatives for radioprotection/radiomitigation
    Patent number: 8906965
    Abstract: Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: December 9, 2014
    Assignee: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Duane Douglas Miller, Mostafa Waleed Gaber, Karin Emmons Thompson, Kui Zeng, Jordan J. Toutounchian
  • METHOD FOR REGULATING RETINAL ENDOTHELIAL CELL VIABILITY
    Publication number: 20140094518
    Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.
    Type: Application
    Filed: November 7, 2013
    Publication date: April 3, 2014
    Applicant: The University of Tennessee Research Foundation
    Inventors: Charles Ryan Yates, Jena Steinle Smith, Duane Douglas Miller, Jordan J. Toutounchian
  • Anti-Inflammatory Quinic Acid Derivatives for Radioprotection/Radiomitigation
    Publication number: 20120283331
    Abstract: Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 8, 2012
    Applicant: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Charles Ryan Yates, Duane Douglas Miller, Mostafa Waleed Gaber, Karin Emmons Thompson, Kui Zeng, Jordan J. Toutounchian