Abstract: The present invention provides biodegradable, biomimetic particles for interacting with cells, including immune cells. In various embodiments, the particles comprise a polymer blend comprising a polyester, such as poly(lactic-co-glycolic acid) (PLGA) and a polyamine, such as poly(beta-amino ester) (PBAE). The particles further comprise, on their surface, one or more ligands for one or more cell surface receptor(s) or cell surface molecule(s). In some embodiments, the cell surface receptor or cell surface molecule is on an immune cell, such as a lymphocyte (T cell or B cell), natural killer cell, dendritic cell, or other cell of the immune system or tumor microenvironment.

Abstract: A facility for estimating a subject home's value is described. For each of one or more direct home attributes, the facility determines the value of the direct home attribute for the subject home. For each of a plurality of arbitrary geographic regions of different sizes containing the subject home, the facility determines information relating to the geographic region as a whole. The facility then subjects the determined values and information to a statistical home valuation model to obtain an estimated value of the subject home.

Abstract: A facility for estimating a subject home's value is described. For each of one or more direct home attributes, the facility determines the value of the direct home attribute for the subject home. For each of a plurality of arbitrary geographic regions of different sizes containing the subject home, the facility determines information relating to the geographic region as a whole. The facility then subjects the determined values and information to a statistical home valuation model to obtain an estimated value of the subject home.