Patents by Inventor Jordan Straight

Jordan Straight has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nato3 mutant polypeptides and uses thereof
    Patent number: 11111279
    Abstract: The present invention relates to isolated Nato3 mutant polypeptides. Methods for stimulating a brain cell to differentiate into a dopaminergic progenitor neuronal cell or a dopaminergic neuron comprises increasing phosphorylation of Nato3 in the brain cells and culturing the brain cells until a progenitor dopaminergic neuronal cell marker or a dopaminergic neuronal cell marker is expressed in the cultured brain cells. Methods for treating Parkinson's disease (PD) in a subject comprises administering to the subject in need thereof, a composition comprising progenitor dopaminergic neuronal cells and/or dopaminergic neuronal cells expressing a Nato3 mutant polypeptide to the brain of the subject.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: September 7, 2021
    Assignee: GRAND VALLEY STATE UNIVERSITY
    Inventors: Merritt DeLano-Taylor, Jordan Straight, Doug Peterson, Nick Huisingh, Daniel Doyle
  • NATO3 MUTANT POLYPEPTIDES AND USES THEREOF
    Publication number: 20180346530
    Abstract: The present invention relates to isolated Nato3 mutant polypeptides. Methods for stimulating a brain cell to differentiate into a dopaminergic progenitor neuronal cell or a dopaminergic neuron comprises increasing phosphorylation of Nato3 in the brain cells and culturing the brain cells until a progenitor dopaminergic neuronal cell marker or a dopaminergic neuronal cell marker is expressed in the cultured brain cells. Methods for treating Parkinson's disease (PD) in a subject comprises administering to the subject in need thereof, a composition comprising progenitor dopaminergic neuronal cells and/or dopaminergic neuronal cells expressing a Nato3 mutant polypeptide to the brain of the subject.
    Type: Application
    Filed: November 18, 2016
    Publication date: December 6, 2018
    Inventors: Merritt Taylor, Jordan Straight, Doug Peterson, Nick Huisingh, Daniel Doyle