Patents by Inventor Jordan Tremaine Despanie

Jordan Tremaine Despanie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation of hemoglobin-based oxygen carriers using elastin-like polypeptides
    Patent number: 11124559
    Abstract: Described herein is the use of elastin-like polypeptides to generate hemoglobin-based oxygen carriers as a means of preventing and treating conditions caused by blood loss or anemia, for example, hemorrhagic shock. Elastin-like polypeptides are capable of creating therapeutically functional fusion proteins through genetic engineering with a therapeutic agent, for example, hemoglobin and biologic equivalent thereof. Specific forms of these fusion proteins have the ability to form into spherical nanoparticles possessing a therapeutically agent at their core. This provides a unique basis for employing elastin-like polypeptides as hemoglobin carriers in the manufacture of blood substitutes.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: September 21, 2021
    Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Jordan Tremaine Despanie, Hao Guo, John Andrew MacKay
  • GENERATION OF HEMOGLOBIN-BASED OXYGEN CARRIERS USING ELASTIN-LIKE POLYPEPTIDES
    Publication number: 20200062825
    Abstract: Described herein is the use of elastin-like polypeptides to generate hemoglobin-based oxygen carriers as a means of preventing and treating conditions caused by blood loss or anemia, for example, hemorrhagic shock. Elastin-like polypeptides are capable of creating therapeutically functional fusion proteins through genetic engineering with a therapeutic agent, for example, hemoglobin and biologic equivalent thereof. Specific forms of these fusion proteins have the ability to form into spherical nanoparticles possessing a therapeutically agent at their core. This provides a unique basis for employing elastin-like polypeptides as hemoglobin carriers in the manufacture of blood substitutes.
    Type: Application
    Filed: November 30, 2018
    Publication date: February 27, 2020
    Inventors: Jordan Tremaine Despanie, Hao Guo, John Andrew MacKay
  • GENERATION OF HEMOGLOBIN-BASED OXYGEN CARRIERS USING ELASTIN-LIKE POLYPEPTIDES
    Publication number: 20160168228
    Abstract: Described herein is the use of elastin-like polypeptides to generate hemoglobin-based oxygen carriers as a means of preventing and treating conditions caused by blood loss or anemia, for example, hemorrhagic shock. Elastin-like polypeptides are capable of creating therapeutically functional fusion proteins through genetic engineering with a therapeutic agent, for example, hemoglobin and biologic equivalent thereof. Specific forms of these fusion proteins have the ability to form into spherical nanoparticles possessing a therapeutically agent at their core. This provides a unique basis for employing elastin-like polypeptides as hemoglobin carriers in the manufacture of blood substitutes.
    Type: Application
    Filed: December 10, 2015
    Publication date: June 16, 2016
    Inventor: Jordan Tremaine Despanie