Patents by Inventor Jordan U. Gutterman

Jordan U. Gutterman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AVICIN D FOR TREATMENT OF MANTLE CELL LYMPHOMA
    Publication number: 20160243142
    Abstract: In some aspects, methods are provided for the treatment of mantle cell lymphoma (MCL) in a patient comprising administering a therapeutically relevant or effective amount of avicin D to the patient.
    Type: Application
    Filed: February 22, 2016
    Publication date: August 25, 2016
    Applicant: Research Development Foundation
    Inventors: Jordan U. GUTTERMAN, Valsala HARIDAS
  • Triterpene compositions and methods for use thereof
    Patent number: 8324177
    Abstract: The invention provides saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: December 4, 2012
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF
    Publication number: 20110294752
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Application
    Filed: June 14, 2011
    Publication date: December 1, 2011
    Applicant: RESEARCH DEVELOPMENT FOUNDATION
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • Triterpene compositions and methods for use thereof
    Patent number: 7985435
    Abstract: The invention provides saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: July 26, 2011
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • Avicin coated stents
    Patent number: 7780974
    Abstract: The invention provides novel compositions and methods related to stents, such as coronary stents, comprising avicins, which are triterpene saponin compositions. In particular aspects of the invention, the avicins have growth-inhibiting properties and/or anti-inflammatory properties. In specific embodiments of the invention, the stent comprising the avicin reduces at least in part restenosis, such as that associated with stent procedures.
    Type: Grant
    Filed: September 20, 2005
    Date of Patent: August 24, 2010
    Assignee: Research Development Foundation
    Inventor: Jordan U. Gutterman
  • TRITERPENE COMPOSITIONS AND METHODS FOR USE THEREOF
    Publication number: 20100189824
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Application
    Filed: January 15, 2010
    Publication date: July 29, 2010
    Inventors: CHARLES J. ARNTZEN, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • Triterpene compositions and methods for use thereof
    Patent number: 7670632
    Abstract: The invention provides saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: March 2, 2010
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Patent number: 7105186
    Abstract: The invention provides saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: September 12, 2006
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Patent number: 6962720
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: November 8, 2005
    Assignee: Research Development Foundation
    Inventors: Valsala Haridas, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Patent number: 6746696
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: June 8, 2004
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Patent number: 6689398
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: February 10, 2004
    Assignee: Research Development Foundation
    Inventors: Valsala Haridas, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Publication number: 20030203049
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Application
    Filed: September 9, 2002
    Publication date: October 30, 2003
    Applicant: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Publication number: 20030054052
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Application
    Filed: November 30, 2001
    Publication date: March 20, 2003
    Applicant: Research Development Foundation
    Inventors: Valsala Haridas, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Publication number: 20030039705
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Application
    Filed: November 16, 2001
    Publication date: February 27, 2003
    Applicant: Research Development Foundation
    Inventors: Charles J. Arntzen, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Publication number: 20030031738
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Application
    Filed: November 30, 2001
    Publication date: February 13, 2003
    Applicant: Research Development Foundation
    Inventors: Valsala Haridas, Jordan U. Gutterman
  • Triterpene compositions and methods for use thereof
    Patent number: 6444233
    Abstract: The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: September 3, 2002
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • Antibacterial and antifungal flavanones from Eysenhardtia texana
    Patent number: 6136849
    Abstract: An activity-guided fractionation of a methanol-dichloromethane extract obtained from the aerial parts of Eysenhardtia texana Kunth. (Fabaceae) led to the isolation of two new antibacterial and antifungal flavanones. Their structures were established as 4',5,7-trihydroxy-8-methyl-6-(3-methyl-[2-butenyl])-(2S)-flavanone and 4',5,7-trihydroxy-6-methyl-8-(3-methyl-[2-butenyl])-(2S)-flavanone on the basis of their UV, ID and 2D-NMR spectra. These compounds have potent antibacterial and antifungal activity as measured by bioassay.
    Type: Grant
    Filed: October 6, 1999
    Date of Patent: October 24, 2000
    Inventors: Joseph J. Hoffmann, Gerald A. Wachter, Jordan U. Gutterman
  • Interferon antibody therapeutic compositions having an extended serum half-life
    Patent number: 5055289
    Abstract: A complex of alpha-interferon with a monoclonal antibody complexes with the alpha-interferon without impairing its antiviral activity. The serum half-life of the interferon administered as the complex is substantially increased when compared to that of alpha-interferon administered alone.
    Type: Grant
    Filed: August 19, 1988
    Date of Patent: October 8, 1991
    Assignee: Hybritech Incorporated
    Inventors: James M. Frincke, Barbara W. Unger, Karen G. Burnett, Evan M. Hersh, Michael G. Rosenblum, Jordan U. Gutterman