Abstract: A system is for the sterile filling of containers for pharmaceutical products. The system includes a device for sterilizing containers and a sterilized-containers filling machine. The device for sterilizing containers includes at least a first autoclave. The system includes an automated container-accumulation device and means for automatically transporting the containers sterilized in the autoclave from the autoclave to the sterilized-containers filling machine via the container-accumulation device.

Abstract: A system for the sterile filling of containers for pharmaceutical products, which includes a device for sterilizing containers and a machine for filling sterilized containers, wherein the device for sterilizing containers includes at least one autoclave, and wherein the system includes an automated container-accumulation device and means for automatically transporting the containers sterilized in the autoclave from said autoclave to the container-filling machine via said container-accumulation device.

Abstract: Method of dosing sterile syringes and device for use with said method Method for dosing sterile syringes with medicinal products, which comprises the steps of arranging syringes in a syringe nest and said syringe nest in a device with a cover; sterilising the syringes; loading the devices with the syringes in a dispensing system; uncovering, dosing and covering the syringes by means of a dosing system in the presence of a laminar flow, wherein said device allows the nests to be sterilised and protects the inside of the syringes from suspended particulates by means of the cover.

Abstract: A machine for the preparation of pharmaceutical products in a sterile environment, including at least two stations of a line for preparing pharmaceutical products and automatic transport means for containers of pharmaceutical products, wherein the machine includes a robot positioned inside the machine and robot control means, the robot being a robotic arm which includes movement means for accessing the stations of the machine.

Abstract: A method is for sterilization of flexible bags containing human plasma protein solution with electron beam. The method includes emitting at least one electron beam with energy between 400 and 500 keV. After approximately 10 nsec to 1.5 sec, a second electron beam pulse is emitted with an energy of at least 4 MeV.

Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.

Abstract: An device is for electron-beam irradiation sterilization of flexible bags that may contain human plasma protein solutions for therapeutic use. The device has two electron accelerators, a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. A sterilization method by electron-beam irradiation provides sterilization of such flexible bags. An in-line filling process for flexible bags can use the sterilization device and method.

Abstract: A unit for automatically collecting blood and/or plasma, includes a number of stations for automatically collecting blood and/or plasma and at least one venepuncture robot. The robot has a blood vessel detector. The robot is fitted on a linear guide and is movable on the linear guide. The stations are laid out along the linear guide such that the robot can move along the linear guide to access the stations.

Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.

Abstract: A system for dispensing a liquid in a closed chamber includes at least one rapid transfer port in at least one wall of the closed chamber. In addition, a liquid is dispensed in a closed chamber that includes at least one rapid transfer port in at least one wall of the closed chamber.

Abstract: A system for the sterile filling of containers for pharmaceutical products, which includes a device for sterilizing containers and a machine for filling sterilized containers, wherein the device for sterilizing containers includes at least one autoclave, and wherein the system includes an automated container-accumulation device and means for automatically transporting the containers sterilized in the autoclave from said autoclave to the container-filling machine via said container-accumulation device.

Abstract: A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.

Abstract: A container for sterilizing flexible bags can be for pharmaceutical use. The container includes an upper flat structure including at least one element supporting the flexible bags and designed to accommodate a plug port of the flexible bag. The support element includes at least one fastening element, which is suitable for retaining the flexible bags once they are inserted into the support element. The container also includes a lower receptacle designed to contain the upper flat structure and to couple to the upper flat structure in a detachable manner. The container further includes a cap for hermetically sealing the lower receptacle.

Abstract: A sterilization method includes irradiating flexible bags, in particular, bags of the type that can contain solutions of human plasma proteins for therapeutic use. The sterilization method includes electron beam irradiation. An in-line method for filling flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use can use the sterilization method.

Abstract: A device is for sterilization by electron beam irradiation of flexible bags, in particular flexible bags of the type that can contain solutions of human plasma proteins for therapeutic use. A sterilization method includes irradiating flexible bags by electron beam irradiation. An in-line method for filling flexible can use the sterilization device and method.

Abstract: An automatic device for emptying bags of frozen blood product includes a product removal device, a product reception hopper, a transporter for transporting the bag from a reception area to the product removal device, and at least one cutter located in the path of the bag between the reception area and the product removal device. The at least one cutter is housed in a support configured to oscillate for absorbing energy of impacts of the bag against the cutter and to return the cutter to its initial position.

Abstract: An device is for electron-beam irradiation sterilization of flexible bags that may contain human plasma protein solutions for therapeutic use. The device has two electron accelerators, a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. A sterilization method by electron-beam irradiation provides sterilization of such flexible bags. An in-line filling process for flexible bags can use the sterilization device and method.

Abstract: A container for sterilizing flexible bags can be for pharmaceutical use. The container includes an upper flat structure including at least one element supporting the flexible bags and designed to accommodate a plug port of the flexible bag. The support element includes at least one fastening element, which is suitable for retaining the flexible bags once they are inserted into the support element. The container also includes a lower receptacle designed to contain the upper flat structure and to couple to the upper flat structure in a detachable manner. The container further includes a cap for hermetically sealing the lower receptacle.

Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.

Abstract: Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.