Patents by Inventor Jordi F. Constansa

Jordi F. Constansa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5393758
    Abstract: The present invention relates to new azetidine derivatives of substituted azetidinylpyridonecarboxylic acids, of 1,4-dihydro-4-oxo-3-quinolinecarboxylic, 4-oxo-1,8-naphthyridine-3-carboxylic and 2,3-dihydro-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acids, represented by the general formula I: ##STR1## The present invention also relates to therapeutically acceptable salts of these compounds, a process for preparing them and their application as medicinal products.
    Type: Grant
    Filed: February 3, 1994
    Date of Patent: February 28, 1995
    Assignee: Laboratorios Del Dr. Esteve S.A.
    Inventors: Augusto C. Pinol, Jordi F. Constansa, Juan P. Corominas
  • Patent number: 5128343
    Abstract: The present invention relates to heterocyclic compounds characterized in that they correspond to the general formula I: ##STR1## in which R.sub.1 represents a hydrogen atom or a halogen, n can have the values 1 to 6 and Het represents an azole, or one of its derivatives selected from among imidazole, indazole, tetrahydroindazoles, pyrazole or pyrazoline and which can be represented by the general formula II: ##STR2## in which A and B, always different, represent a carbon atom or a nitrogen atom, the dashed line indicates the possible presence of a double bond between positions 4 and 5, and R.sub.2, R.sub.3 and R.sub.
    Type: Grant
    Filed: February 7, 1990
    Date of Patent: July 7, 1992
    Assignee: Laboratorios del Dr. Esteve
    Inventors: Augusto C. Pinol, Jordi F. Constansa, Juan P. Corominas
  • Patent number: 5098913
    Abstract: Novel heterocyclic compounds, characterized in that they have formula (I) ##STR1## in which R represents a hydrogen atom, a lower alkyl radical or a phenyl or substituted phenyl radical and R.sub.1 represents an alkyl radical or an aryl radical, and their physiologically acceptable salts.
    Type: Grant
    Filed: February 8, 1991
    Date of Patent: March 24, 1992
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Juan P. Corominas, Augusto C. Pinol, Jordi F. Constansa
  • Patent number: 5087621
    Abstract: The present invention relates to substituted azetidinylisothiazolopyridone derivatives which correspond to the general formula I: ##STR1## or its tautomeric formula ##STR2## It also relates to a process for preparing them and to their application as a medicinal product.
    Type: Grant
    Filed: April 11, 1990
    Date of Patent: February 11, 1992
    Assignee: Laboratorios del Dr. Esteve
    Inventors: Augusto C. Pinol, Jordi F. Constansa, Juan P. Corominas
  • Patent number: 5073646
    Abstract: New azetidines, characterized in that they correspond to the general formula (I) ##STR1## in which R.sub.3 represents an amino radical, an alkylamino radical, a dialkylamino radical, a cycloalkylamino radical, an acylamino radical, an alkylacylamino radical, an aminomethyl radical, an alkylaminomethyl radical, an acylaminomethyl radical or an alkylacylaminomethyl radical, in which radicals each acyl fragment may be substituted with one or more halogen, especially fluorine, atoms; and R.sub.1, R.sub.2, R.sub.4, R.sub.5 and R.sub.6 represent a hydrogen atom or a lower alkyl radical, with the proviso that at least one of them represents a lower alkyl radical, and also their salts.
    Type: Grant
    Filed: June 20, 1990
    Date of Patent: December 17, 1991
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Augusto C. Pinol, Jordi F. Constansa, Juan P. Corominas
  • Patent number: 4943570
    Abstract: Benzimidazole-2-sulfonamide and imidazopyridine-2-sulfonamide derivatives corresponding to the general formula: ##STR1## and their pharmaceutically acceptable salts in which: Z.sup.1 to Z.sup.4 represent a nitrogen atom or a substituted or unsubstituted carbon atom;R.sup.3 represents a hydrogen atom or an alkyl, aryl, heteroaryl, alkylaryl, hydroxyalkyl, alkylheteroaryl, mono-, bi- or tri-cycloalkyl, alkylamino, N-alkyl-alkylamino, alkylcarboxyalkyl, acyl, alkylthioalkyl, alkylsulfinylalkyl or alkylsulfonylalkyl, alkylthioaryl, alkylsulfinylaryl or alkylsulfonylaryl, alkylthioheteroaryl, alkylsulfinylheteroaryl or alkylsulfonylheteroaryl, alkylthioalkylaryl, alkylsulfinylalkylaryl or alkylsulfonylalkylaryl, alkylthioalkylheteroaryl, alkylsulfinylalkylheteroaryl or alkylsulfonylalkylheteroaryl, halogenoalkyl, cyanoalkyl, N-alkylaryl-alkylamino, N-alkyl-N-alkylaryl-alkylamino, N,N-dialkyl-alkylamino, alkylpiperazinyl, alkylpiperidinyl or alkylmorpholinyl radical;X represents --(CHR.sup.8).sub.n --(CHR.sup.9).
    Type: Grant
    Filed: April 28, 1989
    Date of Patent: July 24, 1990
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Jordi F. Constansa, Juan P. Corominas, Augusto C. Pinol
  • Patent number: 4933338
    Abstract: Benzimidazole-2-sulfonamide and imidazopyridine-2-sulfonamide derivatives corresponding to the general formula I: ##STR1## and their pharmaceutically acceptable salts, especially those of the formula in which:Z.sup.1 to Z.sup.4 represent a nitrogen atom or a substituted or unsubstituted carbon atom;R.sup.1 and R.sup.2 represent a hydrogen atom or an alkyl, alkylaryl, alkylcarbonylalkyl, alkylcarbonylaryl, alkylcarbonylheteroaryl, cycloalkyl, carboxyalkyl, acyl or nitro radical, or alternativelyR.sup.1 and R.sup.2 can together form a linkage represented by a group X;R.sup.
    Type: Grant
    Filed: April 15, 1987
    Date of Patent: June 12, 1990
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Jordi F. Constansa, Juan P. Corominas, Agusto C. Pinol
  • Patent number: 4927926
    Abstract: The present invention relates to new heterocyclic compounds, derivatives of 7-(1-azetidinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, characterized in that they correspond to formula (I) ##STR1## The invention also relates to the preparation of these compounds and their applications as medicines.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: May 22, 1990
    Assignee: Laboratorios del Dr. Esteve S.A.
    Inventors: Juan P. Corominas, Jordi F. Constansa, Augusto C. Pinol
  • Patent number: 4791114
    Abstract: The present invention relates to new benzimidazole derivatives, to the process for preparing them and also to their application as medicinal products.The 2-alkylbenzimidazole derivatives according to the present invention correspond to the general formula I ##STR1## and also their therapeutically acceptable salts, in which the substituents are as defined in the specification.
    Type: Grant
    Filed: January 15, 1987
    Date of Patent: December 13, 1988
    Assignee: 501 Laboratorios Del, Dr. Esteve
    Inventors: Jordi F. Constansa, Augusto C. Pinol, Juan P. Corominas