Patents by Inventor Jordi Frigola-Constansa

Jordi Frigola-Constansa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indene derivatives, their preparation and use as medicaments
    Patent number: 8217041
    Abstract: The present invention makes reference to new indene derivatives with general formula (I), as well as to their preparation procedures, their application as medicament and the pharmaceutical compositions containing them. The new compounds of formula (I) show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: July 10, 2012
    Assignee: Laboratories del Sr. Esteve, S.A.
    Inventors: Maria de las Ermitas Alcalde-Pais, Jordi Frigola-Constansa, Joerg Holenz, Ramon Merce-Vidal, Maria de les Neus Mesquida-Estevez, Sara Lopez-Perez
  • ACTIVE SUBSTANCE COMBINATION COMPRISING A COMPOUND WITH NPY RECEPTOR AFFINITY AND A COMPOUND WITH 5-HT6 RECEPTOR AFFINITY
    Publication number: 20120128768
    Abstract: The present invention relates to an active substance combination comprising at least one compound with neuropeptide Y-receptor affinity and at least one compound with 5-HT6 receptor affinity, a medicament comprising said active substance combination, and the use of said active substance combination for the manufacture of a medicament.
    Type: Application
    Filed: January 30, 2012
    Publication date: May 24, 2012
    Applicant: LABORATORIOS DEL DR. ESTEVE S.A
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Alberto Dordal Zueras, Xavier Codony Soler, Ramon Merce Vidal, Jose-Aurelio Castrillo Perez, Jordi Frigola Constansa, Helmut-Heinrich Buschmann
  • Substituted indanyl sulfonamide compounds, their preparation and use as medicaments
    Patent number: 8138210
    Abstract: The present invention refers to new indanyl sulphonamide compounds with general formula (I), as well as to their preparation procedure, their application as medicine and the pharmaceuticals composition which they are made up of. The new compounds of formula I show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.
    Type: Grant
    Filed: August 18, 2006
    Date of Patent: March 20, 2012
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Maria De Las Ermitas Alcalde-Pais, Maria De Les Neus Mesquida-Estevez, Sara Lopez-Perez, Jordi Frigola-Constansa, Joerg Holenz, Ramon Merce-Vidal
  • Substituted pyrazoline compounds for reducing triglycerides in blood
    Patent number: 7998996
    Abstract: The present invention relates to substituted pyrazoline compounds, methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animal.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: August 16, 2011
    Assignee: Laboratorios del Dr. Esteve S.A.
    Inventors: Rosa Cuberes Altisen, Bonifacio Gutierrez Silva, Jordi Frigola-Constansa
  • SUBSTITUTED INDANYL SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS
    Publication number: 20100069378
    Abstract: The present invention refers to new indanyl sulphonamide compounds with general formula (I), as well as to their preparation procedure, their application as medicine and the pharmaceuticals composition which they are made up of. The new compounds of formula (I) show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.
    Type: Application
    Filed: July 25, 2007
    Publication date: March 18, 2010
    Applicant: LABORATORIOS DEL DR. ESTEVE, S.A.
    Inventors: Jordi Frigola-Constansa, Joerg Holenz, Ramon Merce-Vidal, Maria de las Ermitas Alcalde-Pais, Maria de les Neus Mesquida-Estevez, Sara Lopez-Perez
  • INDENE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICAMENTS
    Publication number: 20090163547
    Abstract: The present invention makes reference to new indene derivatives with general formula (I), as well as to their preparation procedures, their application as medicament and the pharmaceutical compositions containing them. The new compounds of formula (I) show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.
    Type: Application
    Filed: November 7, 2006
    Publication date: June 25, 2009
    Inventors: Maria De Las Ermitas Alcalde-Pais, Jordi Frigola-Constansa, Joerg Holenz, Ramon Merce-Vidal, Maria De Les Neus Mesquida-Estevez, Sara Lopez-Perez
  • Substituted pyrazoline compounds, their preparation and use as medicaments
    Patent number: 7524868
    Abstract: The present invention relates to substituted pyrazoline compounds, methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: April 28, 2009
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Rosa Cuberes Altisen, Jordi Frigola Constansa, Sergio Erill Saez
  • Benzoxazinone-derived compounds, their preparation and use as medicaments
    Patent number: 7514429
    Abstract: The present invention relates to Benzoxazinone-derived compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or animals.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: April 7, 2009
    Assignee: ESTEVE Laboratorios Dr. Esteve S.A.
    Inventors: Antoni Torrens Jover, Jose Aurelio Castrillo Perez, Jordi Frigola Constansa, Josep Mas Prió, Alberto Dordal Zueras, Maria Angeles Fisas Escasany
  • Derivatives of sulphonamides, their preparation and use as medicaments
    Patent number: 7498328
    Abstract: The present invention relates to new derivatives of sulphonamides, with the general formula (I), as well as to their physiologically acceptable salts, the processes for their preparation, their application as medicaments in human and/or veterinary therapy and the pharmaceutical compositions that contain them.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: March 3, 2009
    Assignee: Laboratorias Del Dr. Esteve, S.A.
    Inventors: Ramón Merce-Vidal, Blas Andaluz-Mataro, Jordi Frigola-Constansa
  • Derivatives of sulphonamides, their preparation and use as medicaments
    Patent number: 7452881
    Abstract: The present invention relates to new derivatives of sulphonamides, with the general formula (I), as well as to their physiologically acceptable salts, the processes for their preparation, their application as medicaments in human and/or veterinary therapy and the pharmaceutical compositions that contain them.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: November 18, 2008
    Assignee: Laboratories Del Dr. Esteve, S.A.
    Inventors: Ramón Merce-Vidal, Blas Andaluz-Mataro, Jordi Frigola-Constansa
  • Substituted Pyrazoline Compounds for Reducing Triglycerides in Blood
    Publication number: 20080207637
    Abstract: The present invention relates to substituted pyrazoline compounds, methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animal.
    Type: Application
    Filed: February 14, 2005
    Publication date: August 28, 2008
    Inventors: Rosa Cuberes Altisen, Bonifacio Gutierrez Silva, Jordi Frigola- Constansa
  • Substituted indanyl sulfonamide compounds, their preparation and use as medicaments
    Publication number: 20080027073
    Abstract: The present invention refers to new indanyl sulphonamide compounds with general formula (I), as well as to their preparation procedure, their application as medicine and the pharmaceuticals composition which they are made up of. The new compounds of formula I show affinity for 5-HT6 receptors and are, therefore, effective for treating diseases mediated by these receptors.
    Type: Application
    Filed: August 18, 2006
    Publication date: January 31, 2008
    Applicant: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Maria De Las Ermitas Alcalde-Pais, Maria De Les Neus Mesquida-Estevez, Sara Lopez-Perez, Jordi Frigola-Constansa, Joerg Holenz, Ramon Merce-Vidal
  • Derivatives of cyano-aryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines, their preparation and application as medication
    Patent number: 7300937
    Abstract: New derivatives of cyanoaryl (or cyanoheteroaryl)-carbonyl-piperazinyl-pyrimidines (I), where R1 represents an OR3 radical, where R3 represents a radical derived from a saturated hydrocarbon, with a linear or branched chain of 1 to 4 carbon atoms, and R2 represents a phenyl radical substituted at least by one cyan radical (—C?N), or a radical of a heteroaromatic ring of 5 or 6 members substituted at least by one cyan radical (—C?N); and their physiologically acceptable salts, are useful for application in human and/or veterinary therapeutics as sedatives, anticonvulsants, hypnotics and general anaesthetics
    Type: Grant
    Filed: October 10, 2001
    Date of Patent: November 27, 2007
    Assignee: Laboratorios del Dr. Esteve, S.A.
    Inventors: Jordi Corbera-Arjona, David Vano-Domenech, Maria Neus Mesquida-Estevez, Jordi Frigola-Constansa
  • Derivatives of sulphonamides, their preparation and use as medicaments
    Publication number: 20070167448
    Abstract: The present invention relates to new derivatives of sulphonamides, with the general formula (I), as well as to their physiologically acceptable salts, the processes for their preparation, their application as medicaments in human and/or veterinary therapy and the pharmaceutical compositions that contain them.
    Type: Application
    Filed: February 16, 2007
    Publication date: July 19, 2007
    Inventors: Ramon Merce-Vidal, Blas Andaluz-Mataro, Jordi Frigola-Constansa
  • Substituted azetidine compounds, their preparation and use as medicaments
    Patent number: 7232812
    Abstract: The present invention relates to substituted Azetidine compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: June 19, 2007
    Assignee: Laboratorios de Dr. Esteve S.A.
    Inventors: Rosa Cuberes Altisen, Jordi Frigola Constansa, Ines Alvarez Mathieu
  • Substituted azetidine compounds as cyclooxygenase-1-cyclooxygenase-2 inhibitors, and their preparation and use as medicaments
    Publication number: 20070093469
    Abstract: The present invention relates to substituted Azetidine compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Application
    Filed: August 16, 2006
    Publication date: April 26, 2007
    Applicant: LABORATORIOS DEL DR. ESTEVE S.A
    Inventors: Rosa Cuberes Altisen, Jordi Frigola Constansa, Ines Mathieu
  • Substituted azetidine compounds, their preparation and use as medicaments
    Publication number: 20070066587
    Abstract: The present invention relates to substituted Azetidine compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans and animals.
    Type: Application
    Filed: August 17, 2006
    Publication date: March 22, 2007
    Applicant: LABORATORIOS DEL DR. ESTEVE S.A
    Inventors: Rosa Cuberes Altisen, Jordi Frigola Constansa, Bonifacio Gutierrez Silva
  • Pyrazoline derivatives useful for the treatment of cancer
    Publication number: 20070066651
    Abstract: Compounds of formula (I) wherein: X is selected from the group consisting of trihalomethyl, C1-C6 alkyl, and a group of formula (II) wherein: R3 and R4 are independently selected from the group consisting of hydrogen; halogen; hydroxyl; nitro; C1-C6 alkyl; C1-C6 alkoxy; carboxy; C1-C6 trihaloalkyl; and cyano; Z is selected from the group consisting of substituted and unsubstituted aryl; or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of cyclooxygenase-2 activity. They are useful for treating cyclooxygenase-mediated disorders, including, for example, inflamation, neoplastic disorders and angiogenesis-mediated disorders.
    Type: Application
    Filed: August 16, 2006
    Publication date: March 22, 2007
    Applicant: LABORATORIOS DEL DR. ESTEVE S.A.
    Inventors: Rosa Cuberes Altisen, Jordi Frigola Constansa, Ramon Mangues Bafalluy, Isolda Casanova Rigal
  • Active substance combination comprising a compound with npy receptor affinity and a compound with 5-ht6 receptor affinity
    Publication number: 20070059364
    Abstract: The present invention relates to an active substance combination comprising at least one compound with neuropeptide Y-receptor affinity and at least one compound with 5-HT6 receptor affinity, a medicament comprising said active substance combination, and the use of said active substance combination for the manufacture of a medicament.
    Type: Application
    Filed: July 29, 2004
    Publication date: March 15, 2007
    Applicant: Laboratorios Del Dr. Esteve S.A.
    Inventors: Antoni Torrens Jover, Josep Mas Prio, Alberto Dordal Zueras, Xavier Codony Soler, Ramon Merce Vidal, Jose-Aurello Castrillo Perez, Jordi Frigola Constansa, Helmut-Heinrich Buschmann
  • Derivatives of sulphonamides, their preparation and use as medicaments
    Patent number: 7176200
    Abstract: The present invention relates to new derivatives of sulphonamides, with the general formula (I), as well as to their physiologically acceptable salts, the processes for their preparation, their application as medicaments in human and/or veterinary therapy and the pharmaceutical compositions that contain them
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: February 13, 2007
    Assignee: Laboratories Del Dr. Esteve, S.A.
    Inventors: Ramón Merce-Vidal, Blas Andaluz-Mataro, Jordi Frigola-Constansa