Patents by Inventor Jordi Gracia Ferrer

Jordi Gracia Ferrer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolotriazinone derivatives as inhibitors P13K
    Patent number: 9340547
    Abstract: New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: May 17, 2016
    Assignee: Almirall, S.A.
    Inventors: Francisco Javier Bernal Anchuela, Marta Carrascal Riera, Juan Francisco Caturla Javaloyes, Jordi Gracia Ferrer, Victor Giulio Matassa, Emma Terricabras Belart, Joan Taltavull Moll, Montserrat Erra Sola
  • PYRROLOTRIAZINONE DERIVATIVES AS PI3K INHIBITORS
    Publication number: 20150099752
    Abstract: New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).
    Type: Application
    Filed: April 26, 2012
    Publication date: April 9, 2015
    Applicant: ALMIRALL, SA
    Inventors: Francisco Javier Bernal Anchuela, Marta Carrascal Riera, Juan Francisco Caturla Javaloyes, Jordi Gracia Ferrer, Victor Giulio Matassa, Emma Terricabras Belart, Joan Tal Tavul Moll, Montserat Eraa Sola
  • PYRROLOTRIAZINONE DERIVATIVES AS P13K INHIBITORS
    Publication number: 20140163033
    Abstract: New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).
    Type: Application
    Filed: April 26, 2012
    Publication date: June 12, 2014
    Applicant: ALMIRALL, SA
    Inventors: Francisco Javier Bernal Anchuela, Marta Carrascal Riera, Juan Francisco Caturla Javaloyes, Jordi Gracia Ferrer, Victor Giulio Matassa, Emma Terricabras Belart, Joan Tal Tavul Moll, Montserat Eraa Sola
  • Pyridazin-3(2)-one derivatives and their use as PDE4 inhibitors
    Patent number: 7960383
    Abstract: The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives of Formula (I) and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention or suppression of pathological conditions, diseases and disorders known to be susceptible of being improved by inhibition of PDE4 such as asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis or irritable bowel disease.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: June 14, 2011
    Assignee: Laboratorios Almirall SA
    Inventors: Antonia Maria Buil Albero, Vittorio Dal Piaz, Yolanda Garrido Rubio, Jordi Gracia Ferrer, Lluis Miquel Pages Santacana, Joan Taltavull Moll
  • NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES
    Publication number: 20100204241
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4: wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Application
    Filed: October 8, 2008
    Publication date: August 12, 2010
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Paola Giovannoni, Claudia Vergelli
  • NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES
    Publication number: 20090111819
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4: wherein R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Application
    Filed: October 8, 2008
    Publication date: April 30, 2009
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Paola Giovannoni, Claudia Vergelli
  • Pyridazin-3(2H)-one derivatives and their use as PDE4 inhibitors
    Patent number: 7511038
    Abstract: New pyridazin-e-(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: March 31, 2009
    Assignee: Laboratorios Almirall S.A.
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Yolanda Garrido Rubio, Maria Paola Giovannoni, Jordi Gracia Ferrer, Wenceslao Lumeras Amador, Claudia Vergelli
  • Pyridazin-3(2H)-one derivatives
    Patent number: 7491722
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4. R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: February 17, 2009
    Assignee: Laboratorios Almirall S.A.
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Antonia Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Paola Giovannoni, Claudia Vergelli
  • Pyridazin-3(2H)-One Derivatives And Their Use As Pde4 Inhibitors
    Publication number: 20090029996
    Abstract: The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives, to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention and suppression of related pathological conditions, diseases and disorders, in particular asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, topic dermatitis, psoriasis or irritable bowel disease.
    Type: Application
    Filed: June 21, 2005
    Publication date: January 29, 2009
    Inventors: Nuria Aguilar Izquierdo, Marta Carrascal Riera, Vittorio Dal Piaz, Jordi Gracia Ferrer, Wenceslao Lumeras Amador, Maria Del Carmen Masdeu Margalef, Graham Warrellow
  • Pyridothienopyrimidine Derivatives
    Publication number: 20080207645
    Abstract: A pyrido[3?,2?:4,5]thieno[3,2-d]pyrimidine derivative of formula (I) or a pharmaceutically acceptable salt or N-oxide thereof are disclosed, as well as pharmaceutical compositions comprising said compounds and methods of treatment or prevention of a pathological condition or disease susceptible to amelioration by inhibition of phosphodiesterase 4 using said compounds are disclosed.
    Type: Application
    Filed: November 30, 2005
    Publication date: August 28, 2008
    Inventors: Luis Miguel Pages Santacana, Joan Taltavull Moll, Jordi Gracia Ferrer
  • Pyridazin-3(2)-one derivatives and their use as pde4 inhibitors
    Publication number: 20070197536
    Abstract: New pyridazin-e-(2H)-one derivatives having the chemical structure of general formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of phosphodiesterase 4.
    Type: Application
    Filed: November 8, 2004
    Publication date: August 23, 2007
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Buil Albero, Yolanda Garrido Rubio, Maria Giovannoni, Jordi Gracia Ferrer, Wenceslao Lumeras Amador, Claudia Vergelli
  • New pyridazin-3(2h)-one derivatives
    Publication number: 20060173008
    Abstract: Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4. R1, R2 and R4 are organic radicals, R3 is a cyclic group, and R5 is an ester or an aryl or heteroaryl group.
    Type: Application
    Filed: December 22, 2003
    Publication date: August 3, 2006
    Inventors: Vittorio Dal Piaz, Nuria Aguilar Izquierdo, Maria Buil Albero, Marta Carrascal Riera, Jordi Gracia Ferrer, Maria Giovannoni, Claudia Vergelli
  • Pyrrolotriazolopyrimidinone derivatives
    Patent number: 7060824
    Abstract: This invention relates to new therapeutically useful 8-(disubstituted)phenyl-6,9-dihydro-5H-pyrrolo[2,3-e][1,2,4]triazolo[4,3-c]pyrimidine-5-one and 8-phenyl-6,9-dihydro-5H-pyrrolo[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine-5-one derivatives of formula (I): wherein: —X—C—Y— represents (a) or (b) to processes and intermediates for their preparation, to pharmaceutical compositions containing them and to their medical uses as potent and selective inhibitors of phosphodiesterase 5 (PDE 5).
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: June 13, 2006
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Bernat Vidal Juan, Cristina Esteve Trias, Jordi Gracia Ferrer, José Manuel Prieto Soto
  • 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives
    Patent number: 7034016
    Abstract: 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives of formula (I): or a pharmaceutically acceptable salt thereof processes for their preparation, pharmaceutical compositions containing them and their use as PDE 5 inhibitors.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: April 25, 2006
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Jordi Gracia Ferrer, Joan Feixas Gras, José Manuel Prieto Soto, Armando Vega Noverola, Bernat Vidal Juan
  • 6-phenylpyrrolopyrimidinedione derivatives
    Patent number: 6943253
    Abstract: The invention relates to new 6-phenylpyrrolopyrimidine derivatives of formula (I): wherein: —X—C—Y— represents or —X—C—Y— represents and to their use as selective cyclic GMP specific phosphodiesterase (PDE 5)inhibitors, processes for producing them, intermediates used in their production, compositions containing them and their applicability in medical treatment of the human or animal body.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: September 13, 2005
    Assignee: Almirall Prodesfarma S.A.
    Inventors: Bernat Vidal Juan, Jordi Gracia Ferrer, José Manuel Prieto Soto, Armando Vega Noverola
  • 6-phenylpyrrolopyrimidinedione derivatives
    Publication number: 20030232838
    Abstract: The invention relates to new 6-phenylpyrrolopyrimidine derivatives of formula (I): 1
    Type: Application
    Filed: December 6, 2002
    Publication date: December 18, 2003
    Inventors: Bernat Vidal Juan, Jordi Gracia Ferrer, Jose Manuel Prieto Soto, Armando Vega Noverola
  • 8-Phenyl-6, 9-dihydro-[1,2,4] triazolo[3,4-i]purin-5-one derivatives
    Publication number: 20030060627
    Abstract: 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives of formula (I): 1
    Type: Application
    Filed: January 25, 2002
    Publication date: March 27, 2003
    Inventors: Jordi Gracia Ferrer, Joan Feixas Gras, Jose Manuel Prieto Soto, Armando Vega Noverola, Bernat Vidal Juan
  • 1,2,4-triazolo[4,3-B]pyrido[3,2-D]pyridazine derivatives and pharmaceutical compositions containing them
    Publication number: 20020183326
    Abstract: Heterocyclic compounds of formula (I), 1
    Type: Application
    Filed: January 8, 2002
    Publication date: December 5, 2002
    Applicant: ALMIRALL PRODESFARMA, S.A.
    Inventors: Jordi Gracia Ferrer, M. Isabel Crespo Crespo, Armando Vega Noverola, Andres Fernandez Garcia
  • 1,2,4-triazolo(4,3-b)pyrido(3,2-d)pyridazine derivatives and pharmaceutical compositions containing them
    Patent number: 6407108
    Abstract: Heterocyclic compounds of formula(I), wherein R1 represents a hydrogen atom or a —(CH2)m—Y group, wherein m is an integer from 0 to 4 and Y represents an alkyl, haloalkyl, alkoxy, alkoxycarbonyl, C3-C7 cycloalkyl, norbornyl or phenylalkenyl group, or an aromatic group which aromatic group {circumflex over ( )} may optionally be substituted by one or more halogen atoms; R2 represents an aromatic group which aromatic group may optionally be substituted by one or more halogen atoms or alkyl, alkoxy, C3-C6 cycloalkoxy, methylenedioxy, nitro, dialkylamino or trifluoromethyl groups, and R3 represents a hydrogen or halogen atom or an alkyl group, and pharmaceutically acceptable salts thereof, processes for preparing the same are disclosed herein. The compounds are phosphodiesterase 4 inhibitors.
    Type: Grant
    Filed: January 28, 2000
    Date of Patent: June 18, 2002
    Assignee: Almirall Prodesfarma, S.A.
    Inventors: Jordi Gracia Ferrer, Ma Isabel Crespo Crespo, Armando Vega Noverola, Andres Fernandez Garcia