Patents by Inventor Jordi OCHANDO

Jordi OCHANDO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROMOTING TRAINED IMMUNITY WITH THERAPEUTIC NANOBIOLOGIC COMPOSITIONS
    Publication number: 20230355537
    Abstract: The invention relates to therapeutic nanobiologic compositions and methods of treating patients who have cancer, by promoting trained immunity, which is the long-term increased responsiveness, the result of metabolic and epigenetic re-wiring of myeloid cells and their stem cells and progenitors in the bone marrow and spleen and blood induced by a primary insult, and characterized by increased cytokine excretion after re- stimulation with one or multiple secondary stimuli.
    Type: Application
    Filed: December 7, 2022
    Publication date: November 9, 2023
    Inventors: Willem Mulder, Jordi Ochando, Zahi Fayad, Mihai Netea, Leo Joosten
  • TARGETING THE INNATE IMMUNE SYSTEM TO INDUCE LONG-TERM TOLERANCE AND TO RESOLVE MACROPHAGE ACCUMULATION IN ATHEROSCLEROSIS
    Publication number: 20230218537
    Abstract: Methods and compositions for inducing long-term tolerance by hybrid nanoparticles are provided. Compositions and formulations comprising hybrid nanoparticles with inherent affinity for innate immune cells are provided.
    Type: Application
    Filed: March 14, 2023
    Publication date: July 13, 2023
    Inventors: Willem Mulder, Jordi Ochando, Zahi Fayad, Mounia Braza, Raphaël Duivenvoorden, Francois Fay
  • METHODS FOR INHIBITING TRAINED IMMUNITY WITH NANOBIOLOGIC COMPOSITIONS
    Publication number: 20200376102
    Abstract: The invention relates to therapeutic nanobiologic compositions and methods of treating patients who have had an organ transplant, or who suffer from atherosclerosis, arthritis, inflammatory bowel disease including Crohn's, autoimmune diseases including diabetes, and/or autoinflammatory conditions, or after a cardiovascular events, including stroke and myocardial infarction, by inhibiting trained immunity, which is the long-term increased responsiveness, the result of metabolic and epigenetic re-wiring of myeloid cells and their stem cells and progenitors in the bone marrow and spleen and blood induced by a primary insult, and characterized by increased cytokine excretion after re-stimulation with one or multiple secondary stimuli.
    Type: Application
    Filed: April 30, 2020
    Publication date: December 3, 2020
    Inventors: WILLEM MULDER, JORDI OCHANDO, ZAHI FAYAD, RAPHAEL DUIVENVOORDEN, ABRAHAM TEUNISSEN, CARLOS PEREZ-MEDINA, MIHAI NETEA, LEO JOOSTEN
  • NANOBIOLOGIC COMPOSITIONS FOR INHIBITING TRAINED IMMUNITY
    Publication number: 20200376146
    Abstract: The invention relates to therapeutic nanobiologic compositions and methods of treating patients who have had an organ transplant, or who suffer from atherosclerosis, arthritis, inflammatory bowel disease including Crohn's, autoimmune diseases including diabetes, and/or autoinflammatory conditions, or after a cardiovascular events, including stroke and myocardial infarction, by inhibiting trained immunity, which is the long-term increased responsiveness, the result of metabolic and epigenetic re-wiring of myeloid cells and their stem cells and progenitors in the bone marrow and spleen and blood induced by a primary insult, and characterized by increased cytokine excretion after re-stimulation with one or multiple secondary stimuli.
    Type: Application
    Filed: April 30, 2020
    Publication date: December 3, 2020
    Inventors: WILLEM MULDER, JORDI OCHANDO, ZAHI FAYAD, RAPHAEL DUIVENVOORDEN, ABRAHAM TEUNISSEN, CARLOS PEREZ-MEDINA, MIHAI NETEA, LEO JOOSTEN
  • METHODS FOR PROMOTING TRAINED IMMUNITY WITH NANOBIOLOGIC COMPOSITIONS
    Publication number: 20200261591
    Abstract: The invention relates to therapeutic nanobiologic compositions and methods of treating patients who have cancer, by promoting trained immunity, which is the long-term increased responsiveness, the result of metabolic and epigenetic re-wiring of myeloid cells and their stem cells and progenitors in the bone marrow and spleen and blood induced by a primary insult, and characterized by increased cytokine excretion after re-stimulation with one or multiple secondary stimuli.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 20, 2020
    Inventors: WILLEM MULDER, JORDI OCHANDO, ZAHI FAYAD, MIHAI NETEA, LEO JOOSTEN
  • NANOBIOLOGIC COMPOSITIONS FOR PROMOTING TRAINED IMMUNITY
    Publication number: 20200253884
    Abstract: The invention relates to therapeutic nanobiologic compositions and methods of treating patients who have cancer, by promoting trained immunity, which is the long-term increased responsiveness, the result of metabolic and epigenetic re-wiring of myeloid cells and their stem cells and progenitors in the bone marrow and spleen and blood induced by a primary insult, and characterized by increased cytokine excretion after re-stimulation with one or multiple secondary stimuli.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 13, 2020
    Inventors: WILLEM MULDER, JORDI OCHANDO, ZAHI FAYAD, MIHAI NETEA, LEO JOOSTEN
  • TARGETING THE INNATE IMMUNE SYSTEM TO INDUCE LONG-TERM TOLERANCE AND TO RESOLVE MACROPHAGE ACCUMULATION IN ATHEROSCLEROSIS
    Publication number: 20190290593
    Abstract: Methods and compositions for inducing long-term tolerance by hybrid nanoparticles are provided. Compositions and formulations comprising hybrid nanoparticles with inherent affinity for innate immune cells are provided.
    Type: Application
    Filed: May 1, 2017
    Publication date: September 26, 2019
    Applicant: Icahn School of Medicine at Mount Sinai
    Inventors: Willem MULDER, Jordi OCHANDO, Zahi FAYAD, Mounia BRAZA, Raphael DUIVENVOORDEN, Francois FAY