Patents by Inventor Jorg Hendle

Jorg Hendle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HETEROCYCLIC KINASE MODULATORS
    Publication number: 20090156594
    Abstract: The present disclosure provides heterocyclic protein kinase modulators and methods of using these compounds to treat diseases mediated by kinase activity.
    Type: Application
    Filed: May 21, 2008
    Publication date: June 18, 2009
    Applicant: SGX Pharmaceuticals, Inc.
    Inventors: Pierre-Yves Bounaud, Christopher Ronald Smith, Elizabeth A. Jefferson, Jorg Hendle, Patrick S. Lee, Angelina Marie Thayer, Gavin Charles Hirst
  • Crystals and structures of protein kinase CHK2
    Publication number: 20050112746
    Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of CHK2KD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of CHK2KD, CHK2KD crystals and compounds and compositions that affect CHK2 activity.
    Type: Application
    Filed: June 30, 2004
    Publication date: May 26, 2005
    Inventors: Stephen Antonysamy, Jorg Hendle, Gordon Louie
  • Crystals and structures of spleen tyrosine kinase SYKKD
    Publication number: 20040253178
    Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of SYKKD and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of SYKKD, and compounds and compositions that affect SYK activity.
    Type: Application
    Filed: December 17, 2003
    Publication date: December 16, 2004
    Inventors: Shane Atwell, Jorg Hendle, Sean Grant Buchanan, Ingeborg Feil, Marijane Russell, John Badger, Masaki Tomimoto, Michael J. Sauder
  • Crystals and structures of ArnB aminotransferases
    Publication number: 20030105010
    Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of ArnB amino transferases, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of ArnB, and compounds and compositions that affect ArnB activity.
    Type: Application
    Filed: July 12, 2002
    Publication date: June 5, 2003
    Inventors: Janet Newman, John Badger, Brian Noland, Jorg Hendle, Sean Grant Buchanan
  • Crystals and structures of perosamine synthase homologs
    Publication number: 20030101005
    Abstract: The present invention provides machine readable media embedded with the three-dimensional molecular structure coordinates of PLP-dependent enzyme, and subsets thereof, including binding pockets, methods of using the structure to identify and design affecters, including inhibitors and activator, mutants of PSH, and compounds and compositions that affect PSH activity.
    Type: Application
    Filed: July 12, 2002
    Publication date: May 29, 2003
    Inventors: Hans-Joachim Muller-Dieckmann, John Badger, Brian Noland, Jorg Hendle, Sean Grant Buchanan