Abstract: In one embodiment the semiconductor laser comprises a carrier and an edge-emitting laser diode which is mounted on the carrier and which comprises an active zone for generating a laser radiation and a facet with a radiation exit region. The semiconductor laser further comprises a protective cover, preferably a lens for collimation of the laser radiation. The protective cover is fastened to the facet and to a side surface of the carrier by means of an adhesive. A mean distance between a light entrance side of the protective cover and the facet is at most 60 ?m. The semiconductor laser is configured to be operated in a normal atmosphere without additional gas-tight encapsulation.

Abstract: A method for fine boring of internal surfaces of bore holes in work pieces as well as a machining plant for executing this method. The fine machining, fine boring, and honing include fine boring of a bore hole of a work piece using a fine boring tool; transferring the work piece into a honing device; measuring the fine bored bore hole with a measuring device associated with the honing device; and controlling the operation of the fine boring device depending on the bore hole measuring signal received by the measuring device. An output fine boring machining, arranged directly upstream of the transfer, is dimensioned as semi-finishing machining, and is carried out with a fine boring tool having at least one adjustable cutting edge. The position of the adjustable cutting edge is controlled depending on the bore hole measuring signal.

Abstract: Described is a cell line containing (a) three DNA sequences encoding different uptake transporters for organic anions, preferably OATP1B1, OATP1B3 and OATP2B1, operatively linked with a promoter and (b) a DNA sequence encoding an export pump for organic anions or anionic conjugates, preferably the multidrug resistance protein 2 (MRP2), operatively linked with a promoter. Moreover, various uses of said cell line are described, preferably for the identification of transport inhibitors, e.g. drug candidates.