Patents by Inventor Jorg Velker

Jorg Velker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiophene derivatives as S1P1/EDGE1 receptor agonists
    Publication number: 20100048648
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: July 10, 2007
    Publication date: February 25, 2010
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Thiophene derivatives as Sphingosine-1-phosphate-1 receptor agonists
    Patent number: 7605269
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: October 20, 2009
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jörg Velker, Thomas Weller
  • Novel Pyridine Derivatives
    Publication number: 20090005421
    Abstract: The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: January 23, 2007
    Publication date: January 1, 2009
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Novel Thiophene Derivatives as Sphingosine-1-Phosphate-1 Receptor Agonists
    Publication number: 20080318955
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 20, 2006
    Publication date: December 25, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • Novel Thiophene Derivatives
    Publication number: 20080300294
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: November 22, 2006
    Publication date: December 4, 2008
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Novel Thiophene Derivatives as Spingosine-1-Phosphate-1 Receptor Agonists
    Publication number: 20080194670
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 20, 2006
    Publication date: August 14, 2008
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • Hydrogenated Benzo (C) Thiophene Derivatives as Immunomodulators
    Publication number: 20080176926
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 20, 2006
    Publication date: July 24, 2008
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • Quinoline derivatives
    Patent number: 7375227
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: May 20, 2008
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jörg Velker, Thomas Weller
  • Novel piperidine derivatives
    Publication number: 20070010516
    Abstract: The invention relates to novel piperidine derivatives and related compounds of General Formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists, in particular their use as urotensin II antagonists.
    Type: Application
    Filed: May 4, 2004
    Publication date: January 11, 2007
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • Piperazine-alkyl-ureido derivatives
    Publication number: 20060211707
    Abstract: The invention relates to novel piperazine derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: May 4, 2004
    Publication date: September 21, 2006
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea salt
    Publication number: 20060079552
    Abstract: The invention relates to 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline salt or a non defined salt hydrate thereof and a process for its preparation. Further, the present invention relates to the use of said 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline salt alone or in combination with other compounds or formulations of said 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea as a crystalline salt in the preparation of pharmaceutical compositions. The invention also relates to the use of such salts in formulations as neurohormonal antagonists.
    Type: Application
    Filed: October 12, 2004
    Publication date: April 13, 2006
    Inventors: Jorg Velker, Michael Scherz, Thomas Weller
  • 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists
    Publication number: 20050043535
    Abstract: The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: December 2, 2002
    Publication date: February 24, 2005
    Inventors: Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Jorg Velker, Thomas Weller
  • 1,2,3,4-tetrahydroisoquinolines derivatives
    Publication number: 20040242564
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
    Type: Application
    Filed: July 13, 2004
    Publication date: December 2, 2004
    Inventors: Jorg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • 1,2,3,4-Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists
    Patent number: 6815451
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists especially urotensin II antagonists.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: November 9, 2004
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Jörg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • 1 2 3 4 Tetrahydroisoquinolines derivatives as urotensin II receptor antagonists
    Publication number: 20040110744
    Abstract: The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists especially urotensin II antagonists.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 10, 2004
    Inventors: Jorg Velker, Hamed Aissaoui, Christoph Binkert, Martine Clozel, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller