Patents by Inventor Jorge Abraham SOTO-MORENO

Jorge Abraham SOTO-MORENO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Digital microfluidics systems and methods with integrated plasma collection device
    Patent number: 11857969
    Abstract: A digital microfluidics (DMF) device can be used to extract plasma from whole blood and manipulate the extracted plasma. The device can have a plasma separation membrane disposed between a sample inlet and sample outlet that leads into the DMF device. Once the plasma contacts the actuation electrodes of the DMF device, the plasma can be actively extracted from the whole blood sample by actuating the actuation electrodes to pull the plasma through plasma separation membrane.
    Type: Grant
    Filed: August 15, 2022
    Date of Patent: January 2, 2024
    Assignee: mirOculus Inc.
    Inventors: Mais J. Jebrail, Jorge Abraham Soto Moreno, Victor Lee
  • MULTI-CARTRIDGE DIGITAL MICROFLUIDICS APPARATUSES AND METHODS OF USE
    Publication number: 20230398541
    Abstract: High-throughput digital microfluidic (DMF) systems and methods (including devices, systems, cartridges, DMF apparatuses, etc.), are described herein. The systems, apparatuses and methods integrate liquid handling with the DMF apparatuses, providing flexible and efficient sample reactions and sample preparation. These systems, apparatuses and methods may be used with a variety of cartridge configurations and sizes.
    Type: Application
    Filed: August 28, 2023
    Publication date: December 14, 2023
    Inventors: Jorge Abraham SOTO-MORENO, Mais Jehan JEBRAIL, Juan Matias DeCARLI
  • Multi-cartridge digital microfluidics apparatuses and methods of use
    Patent number: 11738345
    Abstract: High-throughput digital microfluidic (DMF) systems and methods (including devices, systems, cartridges, DMF apparatuses, etc.), are described herein. The systems, apparatuses and methods integrate liquid handling with the DMF apparatuses, providing flexible and efficient sample reactions and sample preparation. These systems, apparatuses and methods may be used with a variety of cartridge configurations and sizes.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: August 29, 2023
    Assignee: mirOculus Inc.
    Inventors: Jorge Abraham Soto-Moreno, Mais Jehan Jebrail, Juan Matias DeCarli
  • DIGITAL MICROFLUIDICS DEVICES AND METHODS OF USE THEREOF
    Publication number: 20230219094
    Abstract: Digital microfluidic (DMF) apparatuses and methods for optically-induced heating and manipulating droplets are described herein. DMF apparatuses employing photonic heating as described herein provide radical simplification of routing droplets/reagents in complex, multistep protocols and/or highly plexed workflows.
    Type: Application
    Filed: December 12, 2022
    Publication date: July 13, 2023
    Inventors: Jorge Abraham SOTO-MORENO, Gregory Arthur RAY, Foteini CHRISTODOULOU
  • DIGITAL MICROFLUIDICS SYSTEMS AND METHODS WITH INTEGRATED PLASMA COLLECTION DEVICE
    Publication number: 20230049633
    Abstract: A digital microfluidics (DMF) device can be used to extract plasma from whole blood and manipulate the extracted plasma. The device can have a plasma separation membrane disposed between a sample inlet and sample outlet that leads into the DMF device. Once the plasma contacts the actuation electrodes of the DMF device, the plasma can be actively extracted from the whole blood sample by actuating the actuation electrodes to pull the plasma through plasma separation membrane.
    Type: Application
    Filed: August 15, 2022
    Publication date: February 16, 2023
    Inventors: Mais J. JEBRAIL, Jorge Abraham SOTO MORENO, Victor LEE
  • DIGITAL MICROFLUIDICS SYSTEMS, APPARATUSES AND METHODS OF USING THEM
    Publication number: 20220395835
    Abstract: High-throughput digital microfluidic (DMF) systems and methods (including devices, systems, cartridges, DMF apparatuses, etc.), are described herein. The systems, apparatuses and methods integrate liquid handling with the DMF apparatuses, providing flexible and efficient sample reactions and sample preparation. These systems, apparatuses and methods may be used with a variety of cartridge configurations and sizes.
    Type: Application
    Filed: November 6, 2020
    Publication date: December 15, 2022
    Applicant: MIROCULUS INC.
    Inventors: Jorge Abraham SOTO-MORENO, Mais Jehan JEBRAIL, Juan Matias DE CARLI
  • Digital microfluidics devices and methods of use thereof
    Patent number: 11524298
    Abstract: Digital microfluidic (DMF) apparatuses and methods for optically-induced heating and manipulating droplets are described herein. DMF apparatuses employing photonic heating as described herein provide radical simplification of routing droplets/reagents in complex, multistep protocols and/or highly plexed workflows.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: December 13, 2022
    Assignee: mirOculus Inc.
    Inventors: Jorge Abraham Soto-Moreno, Gregory Arthur Ray, Foteini Christodoulou
  • DIGITAL MICROFLUIDICS DEVICES AND METHODS OF USE THEREOF
    Publication number: 20220297129
    Abstract: Digital microfluidic (DMF) apparatuses and methods for optically-induced heating and manipulating droplets are described herein. DMF apparatuses employing photonic heating as described herein provide radical simplification of routing droplets/reagents in complex, multistep protocols and/or highly plexed workflows.
    Type: Application
    Filed: July 27, 2020
    Publication date: September 22, 2022
    Applicant: MIROCULUS INC.
    Inventors: Jorge Abraham SOTO-MORENO, Gregory Arthur RAY, Foteini CHRISTODOULOU
  • Digital microfluidics systems and methods with integrated plasma collection device
    Patent number: 11413617
    Abstract: A digital microfluidics (DMF) device can be used to extract plasma from whole blood and manipulate the extracted plasma. The device can have a plasma separation membrane disposed between a sample inlet and sample outlet that leads into the DMF device. Once the plasma contacts the actuation electrodes of the DMF device, the plasma can be actively extracted from the whole blood sample by actuating the actuation electrodes to pull the plasma through plasma separation membrane.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: August 16, 2022
    Assignee: MIROCULUS INC.
    Inventors: Mais J. Jebrail, Jorge Abraham Soto Moreno, Victor Lee
  • DIGITAL MICROFLUIDICS DEVICES AND METHODS OF USING THEM
    Publication number: 20220250078
    Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.
    Type: Application
    Filed: April 25, 2022
    Publication date: August 11, 2022
    Inventors: Jorge Abraham SOTO-MORENO, Ik Pyo HONG, Jair Giovanny BELTRAN-VERA, Juan Matias DeCARLI, Jobelo Andres Quintero RODRIGUEZ, Rodolfo WILHELMY-PRECIADO, Mais Jehan JEBRAIL, Gregory RAY, Mathieu Gabriel-Emmanuel CHAULEAU, Paul Mathew LUNDQUIST, Alejandro TOCIGL, John Peter CANNISTRARO, Gareth SCOTT, Spencer SEILER, Rohit LAL, Eugenia CARVAJAL, Eduardo CERVANTES, Nikolay SERGEEV, Yu-Hung CHEN, Poornasree KUMAR, Foteini CHRISTODOULOU
  • DIGITAL MICROFLUIDICS DEVICES AND METHODS OF USING THEM
    Publication number: 20220219172
    Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods that may be used to safely manually add or remove fluid within a cartridge while it is actively applying DMF. Also described herein are DMF readers for use with a DMF cartridges, including those including multiple and/or redundant safety interlocks. Also described herein are DMF reader devices having a cover with active control of microfluidics on the cover while actively controlling DMF on the reader base.
    Type: Application
    Filed: February 28, 2020
    Publication date: July 14, 2022
    Applicant: MIROCULUS INC.
    Inventors: Jorge Abraham SOTO-MORENO, Mais Jehan JEBRAIL, Alejandro TOCIGL, Foteini CHRISTODOULOU, Carl David MARTIN, Morgan Marin WATSON, Rohit LAL, Joshua SHEN, Ronan Barry HAYES, Gregory Arthur RAY, Peter Tirtowijoyo YOUNG, Spencer Todd SEILER, Ik Pyo HONG, Mohan GURUNATHAN, Lubomir DALTCHEV, Rodolfo WILHELMY-PRECIADO, Juan Matias de CARLI, Jobelo Andres Quintero RODRÍGUEZ, Matias Jorge LESCANO
  • Digital microfluidics devices and methods of using them
    Patent number: 11311882
    Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: April 26, 2022
    Assignee: mirOculus Inc.
    Inventors: Jorge Abraham Soto-Moreno, Ik Pyo Hong, Jair Giovanny Beltran-Vera, Juan Matias DeCarli, Jobelo Andres Quintero Rodriguez, Rodolfo Wilhelmy-Preciado, Mais Jehan Jebrail, Gregory Ray, Mathieu Gabriel-Emmanuel Chauleau, Paul Mathew Lundquist, Alejandro Tocigl, John Peter Cannistraro, Gareth Scott, Spencer Seiler, Rohit Lal, Eugenia Carvajal, Eduardo Cervantes, Nikolay Sergeev, Yu-Hung Chen, Poornasree Kumar, Foteini Christodoulou
  • Feedback system for parallel droplet control in a digital microfluidic device
    Patent number: 11298700
    Abstract: Digital microfluidics apparatuses (e.g., devices and systems) configured to determine provide feedback on the location, rate of movement, rate of evaporation and/or size (or other physical characteristic) of one or more, and preferably more than one, droplet in the gap region of a digital microfluidics (DMF) apparatus.
    Type: Grant
    Filed: December 24, 2019
    Date of Patent: April 12, 2022
    Assignee: mirOculus Inc.
    Inventors: Ik Pyo Hong, Irena Barbulovic-Nad, Jorge Abraham Soto-Moreno
  • MULTI-CARTRIDGE DIGITAL MICROFLUIDICS APPARATUSES AND METHODS OF USE
    Publication number: 20200316606
    Abstract: High-throughput digital microfluidic (DMF) systems and methods (including devices, systems, cartridges, DMF apparatuses, etc.), are described herein. The systems, apparatuses and methods integrate liquid handling with the DMF apparatuses, providing flexible and efficient sample reactions and sample preparation. These systems, apparatuses and methods may be used with a variety of cartridge configurations and sizes.
    Type: Application
    Filed: April 8, 2020
    Publication date: October 8, 2020
    Inventors: Jorge Abraham SOTO-MORENO, Mais Jehan JEBRAIL, Juan Matias DeCARLI
  • FEEDBACK SYSTEM FOR PARALLEL DROPLET CONTROL IN A DIGITAL MICROFLUIDIC DEVICE
    Publication number: 20200254458
    Abstract: Digital microfluidics apparatuses (e.g., devices and systems) configured to determine provide feedback on the location, rate of movement, rate of evaporation and/or size (or other physical characteristic) of one or more, and preferably more than one, droplet in the gap region of a digital microfluidics (DMF) apparatus.
    Type: Application
    Filed: December 24, 2019
    Publication date: August 13, 2020
    Inventors: Ik Pyo HONG, Irena BARBULOVIC-NAD, Jorge Abraham SOTO-MORENO
  • DIGITAL MICROFLUIDICS SYSTEMS AND METHODS WITH INTEGRATED PLASMA COLLECTION DEVICE
    Publication number: 20200179933
    Abstract: A digital microfluidics (DMF) device can be used to extract plasma from whole blood and manipulate the extracted plasma. The device can have a plasma separation membrane disposed between a sample inlet and sample outlet that leads into the DMF device. Once the plasma contacts the actuation electrodes of the DMF device, the plasma can be actively extracted from the whole blood sample by actuating the actuation electrodes to pull the plasma through plasma separation membrane.
    Type: Application
    Filed: July 23, 2018
    Publication date: June 11, 2020
    Inventors: Mais J. JEBRAIL, Jorge Abraham SOTO MORENO, Victor LEE
  • Feedback system for parallel droplet control in a digital microfluidic device
    Patent number: 10596572
    Abstract: Digital microfluidics apparatuses (e.g., devices and systems) configured to determine provide feedback on the location, rate of movement, rate of evaporation and/or size (or other physical characteristic) of one or more, and preferably more than one, droplet in the gap region of a digital microfluidics (DMF) apparatus.
    Type: Grant
    Filed: August 22, 2017
    Date of Patent: March 24, 2020
    Assignee: mirOculus Inc.
    Inventors: Ik Pyo Hong, Irena Barbulovic-Nad, Jorge Abraham Soto-Moreno
  • FEEDBACK SYSTEM FOR PARALLEL DROPLET CONTROL IN A DIGITAL MICROFLUIDIC DEVICE
    Publication number: 20190217301
    Abstract: Digital microfluidics apparatuses (e.g., devices and systems) configured to determine provide feedback on the location, rate of movement, rate of evaporation and/or size (or other physical characteristic) of one or more, and preferably more than one, droplet in the gap region of a digital microfluidics (DMF) apparatus.
    Type: Application
    Filed: August 22, 2017
    Publication date: July 18, 2019
    Inventors: Ik Pyo HONG, Irena BARBULOVIC-NAD, Jorge Abraham SOTO MORENO
  • DIGITAL MICROFLUIDICS DEVICES AND METHODS OF USING THEM
    Publication number: 20190168223
    Abstract: Digital microfluidic (DMF) methods and apparatuses (including devices, systems, cartridges, DMF readers, etc.), and in particular DMF apparatuses and methods adapted for large volume. For example, described herein are methods and apparatuses for DMF using an air gap having a width of the gap that may be between 0.3 mm and 3 mm. Also described herein are DMF readers for use with a DMF cartridges, including those adapted for use with large air gap/large volume, although smaller volumes may be used as well.
    Type: Application
    Filed: January 28, 2019
    Publication date: June 6, 2019
    Inventors: Jorge Abraham SOTO-MORENO, Ik Pyo HONG, Jair Giovanny BELTRAN-VERA, Juan Matias DeCARLI, Jobelo Andres QUINTERO, Rodolfo WILHELMY-PRECIADO, Mais Jehan JEBRAIL, Gregory RAY, Mathieu Gabriel-Emmanuel CHAULEAU, Paul Mathew LUNDQUIST, Alejandro TOCIGL, John Peter CANNISTRARO, Gareth SCOTT, Spencer SEILER, Rohit LAL, Eugenia CARVAJAL, Eduardo CERVANTES, Nikolay SERGEEV, Yu-Hung CHEN, Poornasree KUMAR, Foteini CHRISTODOULOU