Abstract: In various embodiments, a molecule exploration application determines one or more potential drug candidates during a drug discovery process. The molecule exploration application generates derived molecule specifications based on a query molecule specification and edit heuristics. Subsequently, the molecule exploration application performs, via a mapping algorithm, one or more mapping operations on the derived molecule specifications to generate mapped molecule specifications. The molecule exploration application then performs one or more search operations on a mapped catalog of molecules based on the mapped molecule specifications to determine the one or more potential drug candidates. Advantageously, the molecule exploration application can be used to efficiently determine additional drug development candidates during a drug discovery process.

Abstract: Method and apparatus for molecular scaffold hopping. Sending instructions, from an interface of a scheduler computer to a job runner computer, the instructions prepared by a processor of the scheduler computer, to perform a plurality of separate computational tasks, wherein each of the separate computational tasks includes calculating one or more chemical properties for a query molecule or for molecules in a library of molecules, wherein one or more of the plurality of separate computational tasks performed on the job runner computer are preemptible computing instances. Receiving status indicators, by the interface, the status indicators sent from the job runner computer, for each of the plurality of separate computational tasks, the indicators are one of: incomplete, completed or failed computing instances.

Abstract: The present application is directed to a method for preparing a cyclic carbonate functional polyester, said method comprising: reacting glycerine carbonate with an anhydride to form an Adduct (A); and, reacting said Adduct (A) with at least one polyepoxide compound to form said cyclic carbonate functional polyester (CC-PES). More particularly, the present application is directed to a method for preparing a cyclic carbonate functional polyester, said method comprising the stages: A) reacting glycerine carbonate with an anhydride to form an Adduct (A); B) providing a polycarboxylic acid; C) reacting said polycarboxylic acid with at least one diglycidyl ether to form an epoxy functional polyester; and, D) reacting said epoxy functional polyester with said Adduct (A) to form said cyclic carbonate functional polyester.

Abstract: The present disclosure relates to compounds of Formula (I) as useful materials for OLED's. At least two of Z1, Z2, Z3, Z4 and Z5 are CN, cyanoaryl, or heteroaryl having at least one nitrogen atom as a ring-constituting atom; and at least two of R1, R2, R3 and R4 are diarylamino, indolyl or carbazolyl.

Abstract: The present disclosure relates to compounds of Formula (I): C-D??(I) as compounds capable of emitting delayed fluorescence, and uses of the compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds of Formula (I) as compounds capable of emitting delayed fluorescence, and uses of these compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds capable of emitting delayed fluorescence, and uses of the compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds of Formula (I), (II), or (III) as compounds capable of emitting delayed fluorescence, and uses of the compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds of formula (I) or formula (II) as compounds capable of emitting delayed fluorescence and uses of these compounds in organic light-emitting diodes.

Abstract: Described herein are molecules for use in organic light emitting diodes comprising at least one moiety A, at least one moiety D, and at least one moiety B.

Abstract: An organic light-emitting device including a first electrode; a second electrode; and an organic layer disposed between the first electrode and the second electrode, wherein the organic layer comprises an emission layer, and wherein the organic layer comprises a first compound represented by Formula 1 and a second compound having the lowest excited triplet energy level greater than 2.73 electron volts: wherein in Formula 1, R11 to R33 are the same as described in the specification.

Abstract: The present disclosure relates to compounds of Formula (I)-(V) as compounds capable of emitting delayed fluorescence and uses of these compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds of Formula (I) as useful materials for OLED's. R is hydrogen or phenyl substituted with at least one alkyl; and D, D? and D? independently have diarylamino or indolyl moiety.

Abstract: An organic light-emitting device including a first electrode; a second electrode; and an organic layer disposed between the first electrode and the second electrode, wherein the organic layer comprises an emission layer, and wherein the organic layer comprises a first compound represented by Formula 1 and a second compound having the lowest excited triplet energy level greater than 2.73 electron volts: wherein in Formula 1, R11 to R33 are the same as described in the specification.

Abstract: The present application is directed to a method for preparing an amino-functional polyester, said method comprising: providing a mixture comprising at least one lactone monomer, a catalyst and a polyamine having at least one primary and at least one secondary amine group; and, subjecting said mixture to ring-opening polymerization conditions.

Abstract: The present disclosure relates to compounds of Formula (I), (II), (III), (IV), or (V): as compounds capable of emitting delayed fluorescence, and uses of the compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds of Formula (I) as useful materials for OLED's. X is O or S; Y1 to Y4 are N or R—C; at least one of R and R5 to R8 is CN or heteroaryl; and at least other one of R and R5 to R8 is diarylamino.

Abstract: The present disclosure relates in parts to compounds capable of emitting delayed fluorescence and uses of these compounds in organic light-emitting diodes.

Abstract: The present disclosure relates to compounds capable of emitting delayed fluorescence, and uses of these compounds in organic light-emitting diodes.

Abstract: The present disclosure relates in part to compounds capable of emitting delayed fluorescence and uses of these compounds in organic light-emitting diodes.