Patents by Inventor Jorge BESSA BELLMUNT

Jorge BESSA BELLMUNT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF HYDROMORPHONE BASE
    Publication number: 20240043447
    Abstract: Hydromorphone hydrochloride (I·HCl) is converted into hydromorphone base (I) via hydromorphone monohydrate (I·H2O).
    Type: Application
    Filed: November 12, 2021
    Publication date: February 8, 2024
    Applicant: Ferrer Internacional, S.A.
    Inventors: Francisco De Asís MARQUILLAS OLONDRIZ, Jorge BESSA BELLMUNT, Antonio Abelino DE LEÓN MARTÍN
  • PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE LAUROXIL
    Publication number: 20220064143
    Abstract: It is provided a process for the preparation of aripiprazole lauroxil that comprises reacting 1-(hydroxymethyl) aripiprazole with lauric acid in the presence of a suitable solvent and a carboxyl activating agent in the presence of a suitable solvent and, optionally, in the presence of an appropriate base. 1-(Hydroxymethyl) aripiprazole can be prepared by reacting aripiprazol or an hydrate thereof with paraformaldehyde in the presence of a suitable organic solvent and a suitable base, wherein the reaction is carried out without the addition of water as a solvent to the reaction mixture. Additionally, (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydro-2-oxoquinolin-1(2H)-yl)methyl formate is provided as a reference standard.
    Type: Application
    Filed: October 14, 2021
    Publication date: March 3, 2022
    Applicant: INTERQUIM, S.A.
    Inventors: Marta POMARES MARCO, Francisco De Asís MARQUILLAS OLONDRIZ, Jorge BESSA BELLMUNT, Antonio Abelino DE LEÓN MARTÍN
  • PROCESS FOR THE PREPARATION OF ARIPIPRAZOLE LAUROXIL
    Publication number: 20200140410
    Abstract: It is provided a process for the preparation of aripiprazole lauroxil that comprises reacting 1-(hydroxymethyl) aripiprazole with lauric acid in the presence of a suitable solvent and a carboxyl activating agent in the presence of a suitable solvent and, optionally, in the presence of an appropriate base. -(Hydroxymethyl) aripiprazole can be prepared by reacting aripiprazole or an hydrate thereof with paraformaldehyde in the presence of a suitable organic 10 solvent and a suitable base, wherein the reaction is carried out without the addition of water as a solvent to the reaction mixture. Additionally, (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydro-2-oxoquinolin-1(2H)-yl)methyl formate is provided as a reference standard.
    Type: Application
    Filed: July 27, 2018
    Publication date: May 7, 2020
    Applicant: INTERQUIM, S.A.
    Inventors: Marta POMARES MARCO, Francisco De Asís MARQUILLAS OLONDRIZ, Jorge BESSA BELLMUNT, Antonio Abelino DE LEÓN MARTÍN