Abstract: The invention provides methods, compositions, and medical kits for treating acute myeloid leukemia using devimistat in combination with cytarabine and mitoxantrone.

Abstract: A composite material includes a thermoplastic polymer matrix throughout which cellulose pulp fibers and filler material are dispersed. The composite may be in solid (e.g. pellet) form, or molten form. The presence of cellulose pulp fibers unexpectedly reduces cycle time, and/or unexpectedly improves certain properties, when the composite is used in injection molding. A method for molding a part includes providing a solid composite that includes thermoplastic polymer, filler material, and cellulose pulp fibers to an injection molding system; melting the polymer to produce a molten mixture; and injecting the molten mixture into a mold. Another method for molding a part includes injecting a molten mixture of thermoplastic polymer, filler material, and cellulose pulp fibers into a mold; and removing the formed part from the mold after a cycle time at least 10% less than that required when using a comparable molten mixture that excludes the pulp fibers.

Abstract: The invention relates in particular to a method for updating security elements cooperating with telecommunications terminals, the updates being performed by an OTA platform on the basis of queries formulated by the security elements, the security elements transmitting PSK-IDs to the OTA platform, the method comprising transmitting, from the security elements to the OTA platform, identities defining an order of priority of requests for handling the queries of same by the OTA platform.

Abstract: The method of making a pellet comprising wood pulp fiber and thermoplastic polymer, comprising extruding an extrudate comprising 10 to 50 weight % wood pulp fiber and 45 to 85 weight % thermoplastic polymer through a die, cutting a pellet from the extrudate, removing the pellet from the extrudate with water having a temperature less than the extrudate, filtering the pellet from the water. In one embodiment the wood pulp fiber in the pellet has a moisture content of 1% or less. In one embodiment the wood fiber does not swell.

Abstract: The method of making a pellet comprising wood pulp fiber and thermoplastic polymer, comprising extruding an extrudate comprising 10 to 50 weight % wood pulp fiber and 45 to 85 weight % thermoplastic polymer through a die, cutting a pellet from the extrudate, removing the pellet from the extrudate with water having a temperature less than the extrudate, filtering the pellet from the water. In one embodiment the wood pulp fiber in the pellet has a moisture content of 1% or less. In one embodiment the wood fiber does not swell.