Patents by Inventor Jorge dos Santos

Jorge dos Santos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TABLET COMPRISING OPICAPONE
    Publication number: 20230181474
    Abstract: The present invention provides a tablet comprising opicapone or a pharmaceutically acceptable salt thereof, having reduced tableting faults during manufacture.
    Type: Application
    Filed: May 26, 2021
    Publication date: June 15, 2023
    Inventors: Koji Taniguchi, Noboru Sekiya, Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima
  • ON-LINE ULTRA PERFORMANCE HYDROPHOBIC INTERACTION CHROMATOGRAPHY FOR MONITORING AT LEAST ONE PRODUCT ATTRIBUTE
    Publication number: 20230018939
    Abstract: The present invention relates to a method of measuring at least one product quality attributes, including critical quality attributes (e.g., oxidation, C-terminal lysine, aggregation, N-terminal glutamine cyclization.) by an online liquid chromatography system, wherein the liquid chromatography system is running a hydrophobic interaction chromatography (HIC) method.
    Type: Application
    Filed: November 20, 2020
    Publication date: January 19, 2023
    Applicant: Merck Sharp & Dohme LLC
    Inventors: Mark A. Brower, Jayesh Desai, Nuno Jorge Dos Santos Pinto, Zachary D. Dunn, Adrian Gospodarek, Xiaoqing Hua, Bhumit A. Patel, Douglas D. Richardson, II
  • PHARMACEUTICAL COMPOSITION COMPRISING LICARBAZEPINE ACETATE
    Publication number: 20210322436
    Abstract: A pharmaceutical composition comprising licarbazepine acetate, especially eslicarbazepine acetate, in combination with suitable excipients, in particular a binder, and a disintegrant. Also disclosed is a granulation process, especially a wet granulation process, for making the pharmaceutical composition.
    Type: Application
    Filed: January 29, 2021
    Publication date: October 21, 2021
    Inventors: Teofilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • PHARMACEUTICAL FORMULATIONS COMPRISING NITROCATECHOL DERIVATIVES AND METHODS OF MAKING THE SAME
    Publication number: 20210315824
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and other derivatives thereof and methods of making the same.
    Type: Application
    Filed: December 15, 2020
    Publication date: October 14, 2021
    Applicants: BIAL - PORTELA & CA, S.A., BIAL - PORTELA & CA, S.A.
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge Jorge dos Santos Lima, Pedro Miguel da Costa Barrocas, Ligia Sofia de Castro Pereira, Rui Cerdeira de Campos Costa
  • FORMULATIONS COMPRISING DOPAMINE-B-HYDROXYLASE INHIBITORS AND METHODS FOR THEIR PREPARATION
    Publication number: 20210169856
    Abstract: The present invention relates to formulations comprising Compound X or a pharmaceutically acceptable salt or solvate thereof: and methods for their preparation.
    Type: Application
    Filed: June 24, 2019
    Publication date: June 10, 2021
    Inventors: Pedro Miguel DA COSTA BARROCAS, Sandra DA SILVA TEIXEIRA BASTOS, Teófilo CARDOSO DE VASCONCELOS, Ricardo Jorge DOS SANTOS LIMA, Ana Rita GONÇALVES DA CRUZ RAMOS PIRES, Raquel QUEIROZ PORTELA MENDES FIGUEIREDO, Jaison CARLOSSO MACHADO
  • Pharmaceutical composition comprising licarbazepine acetate
    Patent number: 10912781
    Abstract: A pharmaceutical composition comprising licarbazepine acetate, especially eslicarbazepine acetate, in combination with suitable excipients, in particular a binder, and a disintegrant. Also disclosed is a granulation process, especially a wet granulation process, for making the pharmaceutical composition.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: February 9, 2021
    Assignee: BIAL-Portela & C.A., S.A.
    Inventors: Teöfilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • PHARMACEUTICAL FORMULATIONS COMPRISING NITROCATECHOL DERIVATIVES AND METHODS OF MAKING THEREOF
    Publication number: 20210023067
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and derivatives thereof and methods of making said compositions and pharmaceutical formulations.
    Type: Application
    Filed: March 5, 2020
    Publication date: January 28, 2021
    Inventors: Teófilo Cardoso De Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • Pharmaceutical formulations compromising nitrocatechol derivatives and methods of making thereof
    Patent number: 10583130
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and derivatives thereof and methods of making said compositions and pharmaceutical formulations.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: March 10, 2020
    Assignee: BIAL-PORTELA & CA, S.A.
    Inventors: Teofilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • PHARMACEUTICAL FORMULATIONS COMPRISING NITROCATECHOL DERIVATIVES AND METHODS OF MAKING THE SAME
    Publication number: 20190008774
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and other derivatives thereof and methods of making the same.
    Type: Application
    Filed: September 5, 2018
    Publication date: January 10, 2019
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Pedro Miguel da Costa Barrocas, Ligia Sofia de Castro Pereira, Rui Cerdeira de Campos Costa
  • PHARMACEUTICAL FORMULATIONS COMPRISING NITROCATECHOL DERIVATIVES AND METHODS OF MAKING THEREOF
    Publication number: 20180333402
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and derivatives thereof and methods of making said compositions and pharmaceutical formulations.
    Type: Application
    Filed: July 31, 2018
    Publication date: November 22, 2018
    Inventors: Teofilo Cardoso de VASCONCELOS, Ricardo Jorge dos SANTOS LIMA, Rui Cerdeira de CAMPOS COSTA
  • Oral Suspension Formulations of Esclicarbazepine Acetate
    Publication number: 20180256594
    Abstract: An oral suspension formulation comprising eslicarbazepine acetate and a pharmaceutically acceptable liquid vehicle.
    Type: Application
    Filed: October 17, 2017
    Publication date: September 13, 2018
    Inventors: Teófilo Cardoso de VASCONCELOS, Ricardo Jorge dos SANTOS LIMA, Rui Cerdeira de CAMPOS COSTA, Pedro Miguel da COSTA BARROCAS, Lígia Sofia de CASTRO PEREIRA
  • Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making thereof
    Patent number: 10071085
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and derivatives thereof and methods of making said compositions and pharmaceutical formulations.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: September 11, 2018
    Assignee: BIAL—Portela & CA, S.A.
    Inventors: Teofilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • Pharmaceutical Composition Comprising Licarbazepine Acetate
    Publication number: 20170112850
    Abstract: A pharmaceutical composition comprising licarbazepine acetate, especially eslicarbazepine acetate, in combination with suitable excipients, in particular a binder, and a disintegrant. Also disclosed is a granulation process, especially a wet granulation process, for making the pharmaceutical composition.
    Type: Application
    Filed: January 4, 2017
    Publication date: April 27, 2017
    Inventors: Teofilo Cardoso de VASCONCELOS, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • Pharmaceutical composition comprising licarbazepine acetate
    Patent number: 9566244
    Abstract: A pharmaceutical composition comprising licarbazepine acetate, especially eslicarbazepine acetate, in combination with suitable excipients, in particular a binder, and a disintegrant. Also disclosed is a granulation process, especially a wet granulation process, for making the pharmaceutical composition.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: February 14, 2017
    Assignee: BIAL-PORTELE & CA, S.A.
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • PHARMACEUTICAL FORMULATIONS COMPRISING NITROCATECHOL DERIVATIVES AND METHODS OF MAKING THEREOF
    Publication number: 20150359783
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and derivatives thereof and methods of making said compositions and pharmaceutical formulations.
    Type: Application
    Filed: August 13, 2015
    Publication date: December 17, 2015
    Inventors: Teofilo Cardoso de VASCONCELOS, Ricardo Jorge dos SANTOS LIMA, Rui Cerdeira de CAMPOS COSTA
  • Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making thereof
    Patent number: 9132094
    Abstract: The present disclosure relates to compositions and pharmaceutical formulations comprising at least one active pharmaceutical ingredient chosen from nitrocatechol derivatives of formula I as defined herein and salts, esters, hydrates, solvates and derivatives thereof and methods of making said compositions and pharmaceutical formulations.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: September 15, 2015
    Assignee: BIAL—Portela & Ca, S.A.
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • Composition
    Publication number: 20140343043
    Abstract: A pharmaceutical composition comprising licarbazepine acetate, especially eslicarbazepine acetate, in combination with suitable excipients, in particular a binder, and a disintegrant. Also disclosed is a granulation process, especially a wet granulation process, for making the pharmaceutical composition.
    Type: Application
    Filed: December 17, 2013
    Publication date: November 20, 2014
    Applicant: BIAL - PORTELA & C.A., S.A.
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • Oral Suspension Formulations of Esclicarbazepine Acetate
    Publication number: 20130040939
    Abstract: An oral suspension formulation comprising eslicarbazepine acetate and a pharmaceutically acceptable liquid vehicle.
    Type: Application
    Filed: September 10, 2010
    Publication date: February 14, 2013
    Applicant: BIAL - PORTELA & CA, S.A.
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa, Pedro Miguel da Costa Barrocas, Ligia Sofia de Castro Pereira
  • Pharmaceutical composition comprising licarbazepine acetate
    Patent number: 8372431
    Abstract: A pharmaceutical composition comprising licarbazepine acetate, especially eslicarbazepine acetate, in combination with suitable excipients, in particular a binder, and a disintegrant. Also disclosed is a granulation process, especially a wet granulation process, for making the pharmaceutical composition.
    Type: Grant
    Filed: October 23, 2008
    Date of Patent: February 12, 2013
    Assignee: BIAL-Portela & C.A., S.A.
    Inventors: Teófilo Cardoso de Vasconcelos, Ricardo Jorge dos Santos Lima, Rui Cerdeira de Campos Costa
  • Method for joining tube plates and tubes as well as friction tool to carry out the method
    Patent number: 7954691
    Abstract: The invention relates to a method for the joining of tube plates (10) and tubes (11) in a tube bundle heat transfer device with the help of a rotating friction tool. Here, the friction tool is rotatingly moved into the open end of a tube (11) surrounded by the tube plate (10) in the axial direction of said tube and pressed against the face of the tube (11) in the manner that the tube end (12) and the region of the tube plate (10) surrounding the tube end are plasticized and merge into a weld joint.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: June 7, 2011
    Assignees: Linde Aktiengesellschaft, GKSS-Forschungszentrum Geesthacht GmbH
    Inventors: Arne Roos, Jorge Dos Santos, Georg Wimmer