Patents by Inventor Jorge Genovese

Jorge Genovese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11052247
    Abstract: A skin regeneration therapy combining precise bioelectric signals, light, and biologics for skin treatment and regeneration. Precise bioelectric signals give clear instructions to the stimulated cell DNA/RNA to produce specific regenerative proteins on demand. Bioelectric signals give clear instructions to cell membranes on what to let in and what to let out and serve as an equivalent or surrogate of environmental stimuli to cause a cell action in response.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: July 6, 2021
    Assignee: LEONHARDT VENTURES LLC
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Publication number: 20210121681
    Abstract: A method of using a bioelectric stimulator for delivering an electrical signal to a subject's tissue, wherein the bioelectric stimulator utilizes the electrical signal to precisely control protein expression and/or release in the tissue on demand so as to increase milk production in a subject, the method including: delivering selected electrical signals to the subject so as to precisely control protein expressions and/or release to increase milk production in the subject.
    Type: Application
    Filed: April 1, 2019
    Publication date: April 29, 2021
    Inventors: Howard J. Leonhardt, Paul Norman, Jorge Genovese, Leslie Miller
  • Patent number: 10960206
    Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: March 30, 2021
    Assignee: LEONHARDT VENTURES LLC
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Publication number: 20200330753
    Abstract: Described is a bioelectric stimulating device for reducing orthodontic treatment time (braces or aligners) with post-treatment stability enhancement. The device and associated methods provide a native sustainable optimal upregulated expression and/or release of an increase in the quantity of the right cells and proteins over time and in the right sequence to optimize tooth movement with the braces or aligners by accelerating bone resorption at the leading edge of the tooth during movement. This acceleration phenomenon is responsible for being able to shorten orthodontic treatment time. Following the final alignment of the teeth, the same device can utilize the native response and accelerate the tooth/bone interface stability by targeting specific cells and proteins that are responsible for bone deposition (hardening) in order to shorten the retention phase, while greatly decreasing the chance of relapse (instability).
    Type: Application
    Filed: June 29, 2020
    Publication date: October 22, 2020
    Inventors: Howard J. Leonhardt, John Joseph Marchetto, Jorge Genovese, Alex Richardson
  • Publication number: 20200330759
    Abstract: Described is a method of treating a subject diagnosed with cancer, breast cancer, bone cancer, lung cancer, osteoporosis, multiple myeloma, and a combination of any thereof by applying a bioelectric signal or signals that upregulate the expression of Osteoprotegerin (“OPG”) and thus beneficially effect the subject's OPG/RANKL/RANK pathway.
    Type: Application
    Filed: June 26, 2020
    Publication date: October 22, 2020
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Patent number: 10695563
    Abstract: Described is a bioelectric stimulating device for reducing orthodontic treatment time (braces) with post-treatment stability enhancement. The device and associated methods provide a native sustainable optimal release of an increase in the quantity of the right cells and proteins over time and in the right sequence to optimize tooth movement with the braces by accelerating bone resorption at the leading edge of the tooth during movement. This acceleration phenomenon is responsible for being able to shorten orthodontic treatment time. Following the final alignment of the teeth, the same device can utilize the native response and accelerate the tooth/bone interface stability by targeting specific cells and proteins that are responsible for bone deposition (hardening) in order to shorten the retention phase, while greatly decreasing the chance of relapse (instability).
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: June 30, 2020
    Assignee: CALXSTARS BUSINESS ACCELERATOR, INC.
    Inventors: Howard J. Leonhardt, Jorge Genovese, John Joseph Marchetto
  • Patent number: 10646644
    Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: May 12, 2020
    Assignee: CalXStars Business Accelerator, Inc.
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Publication number: 20190030330
    Abstract: Described are a system and method that “reads” cancer tumors real time and custom delivers individualized bioelectric therapy to the patient. For example, the system reads a cancer tumor, and based upon this read, delivers to the subject “a confounding signal” to jam communication within that tumor. A cancer tumor may change its communication patterns and the therapy is designed to change with these patterns, attempting to always jam the relevant communication signaling pathway. The described system includes parameters not tied to communication jamming, which should also be customized to induce apoptosis to the cancer tumor. Such parameters include signals for starving a cancer tumor of blood supply and signals for changing the cancer tumor's surface proteins and/or charge so that the immune system attacks the cancer tumor.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 31, 2019
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Publication number: 20190015661
    Abstract: Described is a skin regeneration therapy. The described therapy combines precise bioelectric signals, light, and biologics for skin treatment and regeneration. Precise bioelectric signals give clear instructions to the stimulated cell DNA/RNA to produce specific regenerative proteins on demand. Bioelectric signals give clear instructions to cell membranes on what to let in and what to let out and serve as an equivalent or surrogate of environmental stimuli to cause a cell action in response.
    Type: Application
    Filed: September 12, 2018
    Publication date: January 17, 2019
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Publication number: 20180064935
    Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.
    Type: Application
    Filed: November 14, 2017
    Publication date: March 8, 2018
    Inventors: Howard J. Leonhardt, Jorge Genovese
  • Publication number: 20170274206
    Abstract: Described is a bioelectric stimulating device for reducing orthodontic treatment time (braces) with post-treatment stability enhancement. The device and associated methods provide a native sustainable optimal release of an increase in the quantity of the right cells and proteins over time and in the right sequence to optimize tooth movement with the braces by accelerating bone resorption at the leading edge of the tooth during movement. This acceleration phenomenon is responsible for being able to shorten orthodontic treatment time. Following the final alignment of the teeth, the same device can utilize the native response and accelerate the tooth/bone interface stability by targeting specific cells and proteins that are responsible for bone deposition (hardening) in order to shorten the retention phase, while greatly decreasing the chance of relapse (instability).
    Type: Application
    Filed: March 28, 2017
    Publication date: September 28, 2017
    Applicant: CalXStars Business Accelerator, Inc.
    Inventors: Howard J. Leonhardt, Jorge Genovese, John Joseph Marchetto
  • Publication number: 20170266371
    Abstract: Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment. Follistatin controlled release is also useful for treating other ailments, such as erectile dysfunction, aortic aneurysm, and failing heart valves.
    Type: Application
    Filed: March 15, 2017
    Publication date: September 21, 2017
    Applicant: CalXStars Business Accelerator, Inc.
    Inventors: Howard J. Leonhardt, Jorge Genovese