Abstract: Pharmaceutical composition comprising growth-hormone releasing peptide 6 (GHRP-6), tartrate buffer at pH 5.0-6.0, and trehalose as stabilizing agent, as well as the use of said composition for the manufacture of a medicament. The invention also provides a kit of parts comprising said pharmaceutical composition and a method of treatment of an individual in need thereof, which entails the administration of a therapeutically effective amount of the pharmaceutical composition comprising of GHRP-6, tartrate buffer at pH 5.0-6.0 and trehalose.

Abstract: Presently disclosed are systems and methods for extrapolating a predictive two-dimensional (2D) segmentation to indicate a predicted region of interest (ROI) in a 2D medical image frame rendered from a set of three-dimensional (3D) medical scan data, wherein the predictive segmentation is based on a user-defined 2D segmentation that annotates the ROI in another image frame rendered from the 3D medical scan data. Present embodiments can utilize a user-defined or user-modified 2D segmentation of a frame to extrapolate predicted 2D segmentations for all of the other frames within a set of 3D medical scan data. This enables present embodiments to effectively annotate the ROI in a series of 2D medical image frames with minimal input from a clinician, reducing the amount of time the clinician spends analyzing the 3D medical scan data.

Abstract: Systems/techniques that facilitate dynamic user-interface comparison between machine learning output and training data are provided. In various embodiments, a system can access a data candidate on which a machine learning classifier is to be executed. In various aspects, the system can generate, via execution of the machine learning classifier, a predicted classification based on the data candidate. In various instances, the system can render, on an electronic display, a confidence graph that visually depicts how well or how poorly the data candidate and the predicted classification fit into an annotated training dataset on which the machine learning classifier has been trained.

Abstract: A computing device is configured to obtain order attribute data characterizing at least one order placed and to obtain rank data characterizing a supply performance versus other supply performances. The computing device can also be configured to obtain recency data characterizing a past supply performance and to determine a probability of an in-full fill rate of the at least one order using a fill rate prediction model. The computing device can also send the probability of the in-full fill rate to a supply partner.

Abstract: Techniques are described that facilitate interactive segmentation of medical images with low latency in a cloud-based medical imaging application. According to an embodiment, a system is provided that comprises a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory. The computer executable components comprise a reception component that receives a compressed representation of a three-dimensional (3D) medical image generated from the 3D medical image by an encoder network of a deep neural network model comprising an encoder network and a decoder network, an interaction component that receives user input relative to a displayed portion of the 3D medical image indicating an object included in the displayed portion for segmentation, and a segmentation component that generates a segmentation mask for the object based on the user input using the compressed representation and the decoder network.

Abstract: The invention relates to an aqueous melatonin composition exhibiting surprising long-term stability and allowing high concentrations of said water-insoluble active ingredient. The properties of said composition render it useful as an injectable, for example, for the intravenous administration thereof.

Abstract: This disclosure provides a cross key anti rotation spacer for use in a gas turbine engine. A compressor disk assembly can have a cross key ring having a plurality of keys, teeth, or castellations, alternating with a plurality of gaps to form a cross key surface. The keys or teeth of the cross key surface can mesh with corresponding teeth formed on a spacer of a compressor rotor assembly. The spacer teeth, in connection with the teeth or keys of the cross key ring can prevent rotation between the spacer and compressor disk. This is particularly beneficial during transient operations, such as startup and shutdown of the gas turbine engine.

Abstract: This disclosure provides a cross key anti rotation spacer for use in a gas turbine engine. A compressor disk assembly can have a cross key ring having a plurality of keys, teeth, or castellations, alternating with a plurality of gaps to form a cross key surface. The keys or teeth of the cross key surface can mesh with corresponding teeth formed on a spacer of a compressor rotor assembly. The spacer teeth, in connection with the teeth or keys of the cross key ring can prevent rotation between the spacer and compressor disk. This is particularly beneficial during transient operations, such as startup and shutdown of the gas turbine engine.

Abstract: A liquid propellant driven hydraulic pressure supply device may include an elongated body having an internal bore extending from a power end to a discharge end having a discharge port, a hydraulic fluid disposed in the bore between a piston and the discharge end and a liquid propellant gas generator connected to the power end.

Abstract: A pressure supply device in accordance to one or more aspects includes an elongated body having an internal bore extending from a power end to a discharge end having a discharge port, two or more gas generators connected to the power end and a hydraulic fluid disposed in the bore between a piston and the discharge end. The ignition of one of the gas generators drives the piston to exhaust a partial volume of the hydraulic fluid that is less than the total operational volume of the hydraulic fluid under pressure to operate at a connected device.

Abstract: A method and a system for smooth streaming of media content in a distributed content delivery network, including encoding original media files; providing the encoded original media files to an indexer entity; calculating, the indexer entity, index jump tables for all the encoded original media files; ingesting the index jump tables and the encoded original media files to an origin server; requesting an end user to a SSS a stream fragment; retrieving, the SSS from the origin server, a specific index jump table associated to the requested stream fragment, and using the table to find out and retrieve, from the origin Server, a needed encoded original media file block; and retrieving, the SSS, the requested stream fragment out of the encoded media file block, and sending the requested stream fragment to the end user.

Abstract: A system and method for detecting the rotation breakaway of a spacer from a compressor rotor disk are disclosed herein. The method includes detecting a disk sensed feature and a spacer sensed feature on the compressor rotor disk and the spacer respectively. The method also includes comparing the timing between the two to a predetermined threshold to determine whether the relative position of the spacer to the compressor rotor disk exceeds a predetermined amount. The predetermined amount may be selected to determine whether an imbalance, rubbing, or binding can occur in the gas turbine engine or to determine whether anti-rotation features have been broken.

Abstract: A system and method for detecting the rotation breakaway of a spacer from a compressor rotor disk are disclosed herein. The method includes detecting a disk sensed feature and a spacer sensed feature on the compressor rotor disk and the spacer respectively. The method also includes comparing the timing between the two to a predetermined threshold to determine whether the relative position of the spacer to the compressor rotor disk exceeds a predetermined amount. The predetermined amount may be selected to determine whether an imbalance, rubbing, or binding can occur in the gas turbine engine or to determine whether anti-rotation features have been broken.

Abstract: Methods and apparatus are provided for processing data representing three-dimensional points organized in a data structure wherein each point has multiple components, the data is organized in a respective layer per component, each layer is segmented in cells of a two-dimensional grid, the cells are arranged such that the components of a given point are contained in corresponding cells of multiple layers, the cells are grouped in patches by layer, and the patches are arranged such that the components of an array of points is represented by corresponding patches of multiple layers. At least one first criterion and at least one second criterion are obtained. Data are retrieved from cells of patches meeting the at least one first criterion and from layers meeting the at least one second criterion. The retrieved data are processed to obtain a derivative data set.

Abstract: The invention relates to an aqueous melatonin composition exhibiting surprising long-term stability and allowing high concentrations of said water-insoluble active ingredient. The properties of said composition render it useful as an injectable, for example, for the intravenous administration thereof.

Abstract: A pressure supply device in accordance to one or more aspects includes an elongated body having an internal bore extending from a power end to a discharge end having a discharge port, two or more gas generators connected to the power end and a hydraulic fluid disposed in the bore between a piston and the discharge end. The ignition of one of the gas generators drives the piston to exhaust a partial volume of the hydraulic fluid that is less than the total operational volume of the hydraulic fluid under pressure to operate at a connected device.

Abstract: A liquid propellant driven hydraulic pressure supply device may include an elongated body having an internal bore extending from a power end to a discharge end having a discharge port, a hydraulic fluid disposed in the bore between a piston and the discharge end and a liquid propellant gas generator connected to the power end.

Abstract: A method and a system for smooth streaming of media content in a distributed content delivery network, including encoding original media files; providing the encoded original media files to an indexer entity; calculating, the indexer entity, index jump tables for all the encoded original media files; ingesting the index jump tables and the encoded original media files to an origin server; requesting an end user to a SSS a stream fragment; retrieving, the SSS from the origin server, a specific index jump table associated to the requested stream fragment, and using the table to find out and retrieve, from the origin Server, a needed encoded original media file block; and retrieving, the SSS, the requested stream fragment out of the encoded media file block, and sending the requested stream fragment to the end user.

Abstract: Methods and apparatus are provided for processing data representing three-dimensional points organized in a data structure wherein each point has multiple components, the data is organized in a respective layer per component, each layer is segmented in cells of a two-dimensional grid, the cells are arranged such that the components of a given point are contained in corresponding cells of multiple layers, the cells are grouped in patches by layer, and the patches are arranged such that the components of an array of points is represented by corresponding patches of multiple layers. At least one first criterion and at least one second criterion are obtained. Data are retrieved from cells of patches meeting the at least one first criterion and from layers meeting the at least one second criterion. The retrieved data are processed to obtain a derivative data set.

Abstract: Disclosed are platforms, systems, media, and methods comprising: a software module configured to allow generation of a dare campaign, a dare campaign having parameters comprising a creator, a target, a challenge, funds raised, and a beneficiary; and a software module configured to generate a dare campaign community, a dare campaign community organized around a primary dare campaign and characterized by one or more of: a primary dare campaign having a challenge defined by a community member other than the creator or the target; one or more child dare campaigns, wherein a child dare campaign has parameters defaulted to those of the primary dare campaign, wherein the parameters are customizable by the creator of the child dare campaign; and one or more clone dare campaigns, wherein a clone dare campaign has parameters linked to the primary dare campaign, wherein the linked parameters include at least the challenge.