Patents by Inventor Jorge Otero-Millan

Jorge Otero-Millan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240188879
    Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.
    Type: Application
    Filed: February 19, 2024
    Publication date: June 13, 2024
    Applicants: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
  • Patent number: 11903720
    Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: February 20, 2024
    Assignees: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
  • Publication number: 20230200641
    Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.
    Type: Application
    Filed: March 6, 2023
    Publication date: June 29, 2023
    Applicant: Dignity Health
    Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
  • Patent number: 11602273
    Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: March 14, 2023
    Assignee: DIGNITY HEALTH
    Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
  • Publication number: 20220245812
    Abstract: A user device may receive video associated with a patient, wherein the video depicts physiological activity involving the patient. The user device may receive profile information associated with the patient. The user device may obtain, from the video, image data using an image processing model. The user device may analyze the image data to generate a patient signature associated with the image data, wherein the patient signature is representative of the physiological activity. The user device may access a reference data structure that includes a plurality of reference signatures. The user device may identify that the patient signature is associated with a reference signature of the plurality of reference signatures, wherein the reference signature is associated with a health condition. The user device may perform an action associated with the health condition and the patient.
    Type: Application
    Filed: July 23, 2020
    Publication date: August 4, 2022
    Inventors: David E. NEWMAN-TOKER, Jorge OTERO-MILLAN, Taylor Maxwell PARKER, Nathan FARRELL
  • Publication number: 20200146611
    Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.
    Type: Application
    Filed: January 13, 2020
    Publication date: May 14, 2020
    Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
  • Patent number: 10646723
    Abstract: The present invention is directed to a magnetic vestibular stimulation (MVS) system for rehabilitation of subjects with vestibular and balance disorders. The magnetic vestibular stimulation system includes a magnet and a cooling system. In some embodiments, the subject wears video goggles in order to stimulate the subject to orient to a virtual reality. The subject can lie, sit or stand in or near a strong magnetic field generated by the system. The magnetic field generated by the system stimulates the vestibular system to counteract the inherent imbalance created by a naturally-occurring vestibular disorder. Particularly important, the direction and amplitude of vestibular stimulation can be easily manipulated by altering the orientation and distance of the head relative to the magnetic field vector. Thus, MVS can be precisely tailored to a patient's specific pattern of vestibular disturbance.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: May 12, 2020
    Assignee: The Johns Hopkins University
    Inventors: Daniel H. Reich, Collin L. Broholm, David Zee, Dale Roberts, Michael C. Schubert, Jorge Otero-Millan, Bryan Ward
  • Patent number: 10537276
    Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: January 21, 2020
    Assignees: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
  • Publication number: 20180235531
    Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
  • Patent number: 9962119
    Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and infersaccatic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.
    Type: Grant
    Filed: April 23, 2014
    Date of Patent: May 8, 2018
    Assignees: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
  • Publication number: 20180116507
    Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.
    Type: Application
    Filed: December 29, 2017
    Publication date: May 3, 2018
    Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
  • Publication number: 20180036549
    Abstract: The present invention is directed to a magnetic vestibular stimulation (MVS) system for rehabilitation of subjects with vestibular and balance disorders. The magnetic vestibular stimulation system includes a magnet and a cooling system. In some embodiments, the subject wears video goggles in order to stimulate the subject to orient to a virtual reality. The subject can lie, sit or stand in or near a strong magnetic field generated by the system. The magnetic field generated by the system stimulates the vestibular system to counteract the inherent imbalance created by a naturally-occurring vestibular disorder. Particularly important, the direction and amplitude of vestibular stimulation can be easily manipulated by altering the orientation and distance of the head relative to the magnetic field vector. Thus, MVS can be precisely tailored to a patient's specific pattern of vestibular disturbance.
    Type: Application
    Filed: August 4, 2017
    Publication date: February 8, 2018
    Inventors: Daniel H. Reich, Collin L. Broholm, David Zee, Dale Roberts, Michael C. Schubert, Jorge Otero-Millan, Bryan Ward
  • Patent number: 9854966
    Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: January 2, 2018
    Assignee: Dignity Health
    Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
  • Patent number: 9301679
    Abstract: A method and apparatus including identifying a plurality of at least partially repetitive eye movements of a person, the eye movements defined by a first predominantly horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of eye movements and comparing the vertical component with a predetermined threshold value.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: April 5, 2016
    Assignee: Dignity Health
    Inventors: Susana N. Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
  • Publication number: 20140336526
    Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.
    Type: Application
    Filed: November 23, 2012
    Publication date: November 13, 2014
    Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
  • Publication number: 20140221869
    Abstract: A method and apparatus including identifying a plurality of at least partially repetitive eye movements of a person, the eye movements defined by a first predominantly horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of eye movements and comparing the vertical component with a predetermined threshold value.
    Type: Application
    Filed: March 20, 2014
    Publication date: August 7, 2014
    Applicant: DIGNITY HEALTH
    Inventors: Susana N. Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
  • Patent number: 8721081
    Abstract: A method and apparatus are provided for the differential diagnosis of a patient with progressive supranuclear palsy (PSP) from a patient with Parkinson's disease (PD). One method includes identifying a plurality of partially repetitive eye movements that over time define square wave jerks, each square wave jerk of the plurality of square wave jerks defined by a first horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of square wave jerks, comparing the vertical component with a threshold value. PSP or PD is identified by comparison of the vertical component with the threshold value. In another embodiment, a patient's saccade rate is determined and compared to a threshold value, and PSP or PD is identified based upon the comparison of the saccade rate with the threshold value.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: May 13, 2014
    Assignee: Dignity Health
    Inventors: Susana Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
  • Patent number: 8348428
    Abstract: A method and apparatus are provided for characterizing square wave jerks in the eye movements of a person, which may provide a powerful tool in the differential diagnosis of oculomotor and neurological disease. The method includes the steps of a) providing a sequence of saccades, b) identifying pairs of consecutive saccades of the sequence, c) determining whether each saccade of each identified pair is opposite the direction of the other saccade and, if not, then discarding the pair, d) determining whether a magnitude of each saccade of each identified pair is comparable and, if not, then discarding the pair, e) determining whether the pair of saccades of each identified pair are temporally related by a predetermined time period and, if not, then discarding the pair and f) collecting any remaining pairs of saccades as square wave jerks.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: January 8, 2013
    Assignee: Dignity Health
    Inventors: Susana Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
  • Publication number: 20120238903
    Abstract: A method and apparatus are provided for the differential diagnosis of a patient with progressive supranuclear palsy (PSP) from a patient with Parkinson's disease (PD). One method includes identifying a plurality of partially repetitive eye movements that over time define square wave jerks, each square wave jerk of the plurality of square wave jerks defined by a first horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of square wave jerks, comparing the vertical component with a threshold value. PSP or PD is identified by comparison of the vertical component with the threshold value. In another embodiment, a patient's saccade rate is determined and compared to a threshold value, and PSP or PD is identified based upon the comparison of the saccade rate with the threshold value.
    Type: Application
    Filed: January 27, 2012
    Publication date: September 20, 2012
    Inventors: Susana Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
  • Patent number: 7857452
    Abstract: A method and apparatus are provided for identifying the covert foci of attention of a person when viewing an image or series of images. The method includes the steps of presenting the person with an image having a plurality of visual elements, measuring eye movements of the subject with respect to those images, and based upon the measured eye movements triangulating and determining the level of covert attentional interest that the person has in the various visual elements.
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: December 28, 2010
    Assignee: Catholic Healthcare West
    Inventors: Susana Martinez-Conde, Stephen L. Macknik, Jorge Otero-Millan