Patents by Inventor Jorge Otero-Millan
Jorge Otero-Millan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240188879Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.Type: ApplicationFiled: February 19, 2024Publication date: June 13, 2024Applicants: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
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Patent number: 11903720Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.Type: GrantFiled: January 13, 2020Date of Patent: February 20, 2024Assignees: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
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Publication number: 20230200641Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.Type: ApplicationFiled: March 6, 2023Publication date: June 29, 2023Applicant: Dignity HealthInventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
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Patent number: 11602273Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.Type: GrantFiled: December 29, 2017Date of Patent: March 14, 2023Assignee: DIGNITY HEALTHInventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
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Publication number: 20220245812Abstract: A user device may receive video associated with a patient, wherein the video depicts physiological activity involving the patient. The user device may receive profile information associated with the patient. The user device may obtain, from the video, image data using an image processing model. The user device may analyze the image data to generate a patient signature associated with the image data, wherein the patient signature is representative of the physiological activity. The user device may access a reference data structure that includes a plurality of reference signatures. The user device may identify that the patient signature is associated with a reference signature of the plurality of reference signatures, wherein the reference signature is associated with a health condition. The user device may perform an action associated with the health condition and the patient.Type: ApplicationFiled: July 23, 2020Publication date: August 4, 2022Inventors: David E. NEWMAN-TOKER, Jorge OTERO-MILLAN, Taylor Maxwell PARKER, Nathan FARRELL
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Publication number: 20200146611Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.Type: ApplicationFiled: January 13, 2020Publication date: May 14, 2020Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
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Patent number: 10646723Abstract: The present invention is directed to a magnetic vestibular stimulation (MVS) system for rehabilitation of subjects with vestibular and balance disorders. The magnetic vestibular stimulation system includes a magnet and a cooling system. In some embodiments, the subject wears video goggles in order to stimulate the subject to orient to a virtual reality. The subject can lie, sit or stand in or near a strong magnetic field generated by the system. The magnetic field generated by the system stimulates the vestibular system to counteract the inherent imbalance created by a naturally-occurring vestibular disorder. Particularly important, the direction and amplitude of vestibular stimulation can be easily manipulated by altering the orientation and distance of the head relative to the magnetic field vector. Thus, MVS can be precisely tailored to a patient's specific pattern of vestibular disturbance.Type: GrantFiled: August 4, 2017Date of Patent: May 12, 2020Assignee: The Johns Hopkins UniversityInventors: Daniel H. Reich, Collin L. Broholm, David Zee, Dale Roberts, Michael C. Schubert, Jorge Otero-Millan, Bryan Ward
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Patent number: 10537276Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.Type: GrantFiled: April 20, 2018Date of Patent: January 21, 2020Assignees: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
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Publication number: 20180235531Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and intersaccadic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.Type: ApplicationFiled: April 20, 2018Publication date: August 23, 2018Inventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
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Patent number: 9962119Abstract: A system and method of detecting eye movements of a subject for the diagnosis of neurological disorders. The method includes tracking eye movements of the subject, identifying microsaccades from the tracked eye movements, and characterizing microsaccade dynamics of the identified microsaccades to determine one or more parameters, such as microsaccade direction, microsaccade velocity, microsaccade magnitude, microsaccadic peak velocity-magnitude relationship, microsaccade duration, and infersaccatic intervals. The method also includes comparing the one or more determined parameters with a corresponding control parameter, assessing the comparison to determine differences between the one or more determined parameters and the corresponding control parameters, and generating a report including the diagnosis of neurological disorder based on the assessment.Type: GrantFiled: April 23, 2014Date of Patent: May 8, 2018Assignees: DIGNITY HEALTH, LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Stephen L. Macknik, Susana Martinez-Conde, Zoi Kapoula, Jorge Otero-Millan
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Publication number: 20180116507Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.Type: ApplicationFiled: December 29, 2017Publication date: May 3, 2018Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
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Publication number: 20180036549Abstract: The present invention is directed to a magnetic vestibular stimulation (MVS) system for rehabilitation of subjects with vestibular and balance disorders. The magnetic vestibular stimulation system includes a magnet and a cooling system. In some embodiments, the subject wears video goggles in order to stimulate the subject to orient to a virtual reality. The subject can lie, sit or stand in or near a strong magnetic field generated by the system. The magnetic field generated by the system stimulates the vestibular system to counteract the inherent imbalance created by a naturally-occurring vestibular disorder. Particularly important, the direction and amplitude of vestibular stimulation can be easily manipulated by altering the orientation and distance of the head relative to the magnetic field vector. Thus, MVS can be precisely tailored to a patient's specific pattern of vestibular disturbance.Type: ApplicationFiled: August 4, 2017Publication date: February 8, 2018Inventors: Daniel H. Reich, Collin L. Broholm, David Zee, Dale Roberts, Michael C. Schubert, Jorge Otero-Millan, Bryan Ward
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Patent number: 9854966Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.Type: GrantFiled: November 23, 2012Date of Patent: January 2, 2018Assignee: Dignity HealthInventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
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Patent number: 9301679Abstract: A method and apparatus including identifying a plurality of at least partially repetitive eye movements of a person, the eye movements defined by a first predominantly horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of eye movements and comparing the vertical component with a predetermined threshold value.Type: GrantFiled: March 20, 2014Date of Patent: April 5, 2016Assignee: Dignity HealthInventors: Susana N. Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
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Publication number: 20140336526Abstract: A system and method for determining a subject's attentional response to a stimulus. The method includes measuring microsaccadic eye movement dynamics of the subject, detecting whether a microsaccadic signature (a suppression in microsaccadic rate) is present in the measured microsaccadic eye movement relative to a time of the stimulus, and correlating the subject's attentional response to the stimulus based on the detection. The method further includes determining that the stimulus was sensed if the microsaccadic signature is present and determining that the stimulus was not sensed if the microsaccadic signature is absent.Type: ApplicationFiled: November 23, 2012Publication date: November 13, 2014Inventors: Jorge Otero-Millan, Stephen L. Macknik, Susana Martinez-Conde
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Publication number: 20140221869Abstract: A method and apparatus including identifying a plurality of at least partially repetitive eye movements of a person, the eye movements defined by a first predominantly horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of eye movements and comparing the vertical component with a predetermined threshold value.Type: ApplicationFiled: March 20, 2014Publication date: August 7, 2014Applicant: DIGNITY HEALTHInventors: Susana N. Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
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Patent number: 8721081Abstract: A method and apparatus are provided for the differential diagnosis of a patient with progressive supranuclear palsy (PSP) from a patient with Parkinson's disease (PD). One method includes identifying a plurality of partially repetitive eye movements that over time define square wave jerks, each square wave jerk of the plurality of square wave jerks defined by a first horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of square wave jerks, comparing the vertical component with a threshold value. PSP or PD is identified by comparison of the vertical component with the threshold value. In another embodiment, a patient's saccade rate is determined and compared to a threshold value, and PSP or PD is identified based upon the comparison of the saccade rate with the threshold value.Type: GrantFiled: January 27, 2012Date of Patent: May 13, 2014Assignee: Dignity HealthInventors: Susana Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
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Patent number: 8348428Abstract: A method and apparatus are provided for characterizing square wave jerks in the eye movements of a person, which may provide a powerful tool in the differential diagnosis of oculomotor and neurological disease. The method includes the steps of a) providing a sequence of saccades, b) identifying pairs of consecutive saccades of the sequence, c) determining whether each saccade of each identified pair is opposite the direction of the other saccade and, if not, then discarding the pair, d) determining whether a magnitude of each saccade of each identified pair is comparable and, if not, then discarding the pair, e) determining whether the pair of saccades of each identified pair are temporally related by a predetermined time period and, if not, then discarding the pair and f) collecting any remaining pairs of saccades as square wave jerks.Type: GrantFiled: October 31, 2008Date of Patent: January 8, 2013Assignee: Dignity HealthInventors: Susana Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
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Publication number: 20120238903Abstract: A method and apparatus are provided for the differential diagnosis of a patient with progressive supranuclear palsy (PSP) from a patient with Parkinson's disease (PD). One method includes identifying a plurality of partially repetitive eye movements that over time define square wave jerks, each square wave jerk of the plurality of square wave jerks defined by a first horizontal saccadic movement that moves the eye away from a fixation target followed by a corrective saccadic movement towards the target shortly thereafter, measuring a vertical component associated with the plurality of square wave jerks, comparing the vertical component with a threshold value. PSP or PD is identified by comparison of the vertical component with the threshold value. In another embodiment, a patient's saccade rate is determined and compared to a threshold value, and PSP or PD is identified based upon the comparison of the saccade rate with the threshold value.Type: ApplicationFiled: January 27, 2012Publication date: September 20, 2012Inventors: Susana Martinez-Conde, Stephen L. Macknik, Xoana Troncoso, Jorge Otero-Millan
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Patent number: 7857452Abstract: A method and apparatus are provided for identifying the covert foci of attention of a person when viewing an image or series of images. The method includes the steps of presenting the person with an image having a plurality of visual elements, measuring eye movements of the subject with respect to those images, and based upon the measured eye movements triangulating and determining the level of covert attentional interest that the person has in the various visual elements.Type: GrantFiled: August 27, 2008Date of Patent: December 28, 2010Assignee: Catholic Healthcare WestInventors: Susana Martinez-Conde, Stephen L. Macknik, Jorge Otero-Millan