Abstract: The present application relates to aqueous solution compositions of engineered dimeric proteins comprising monomers that comprise at least one human serpin polypeptide operably linked to a human immunoglobulin Fc polypeptide or a polypeptide that is derived from an immunoglobulin Fc polypeptide, at low buffer concentrations and low ionic strength and containing a neutral amino acid. The aqueous solution compositions increase the stability of the an Fc domain in aqueous solution compositions, and in particular increase the stability of an engineered dimeric protein.

Abstract: The present application describes a seat that is attachable to a vehicle. The seat here disclosed comprises a seat, one-piece leg support that tilts over at least one shaft and footrest. The attachable seat comprises at least one shaft that permits joining the seat with the leg support and the respective rotation that permits the tilting of the leg support as a single piece. Additionally, the seat disclosed in the present patent application further comprises a mechanical fixation system that permits easy attachment and release from the vehicle.

Abstract: The invention provides inter alia an aqueous solution composition of pH in the range 4.0-6.0 comprising: —terlipressin or a salt thereof; —optionally one or more buffers being substances having at least one ionisable group with a pKa in the range 3.0 to 7.0 and which pKa is within 1 pH unit of the pH of the composition; —optionally an amino acid; and—optionally a tonicity modifier wherein the buffers are present in the composition at a total concentration of 0-5 mM.

Abstract: There is provided, inter alia, an aqueous solution composition of pH in the range 4.0-7.5 comprising: a peptide therapeutic agent; optionally one or more buffers being substances having at least one ionisable group with a pKa in the range 3.0 to 8.5 and which pKa is within 2 pH units of the pH of the composition; and a stabilizer; wherein the peptide therapeutic agent does not contain ionisable groups with pKa in the range 3.0 to 8.5, and wherein the buffers are present in the composition at a total concentration of 0-5 mM.

Abstract: A method of producing a sock including a gaiter (e.g., knitted integrally in a single garment). The sock further comprises a legging and a foot Upon knitting the legging to a predetermined point and to have a tubular form, first thread used to knit the legging is secured and second thread to knit the gaiter is released. Upon completing the knitting of the gaiter with the second thread, the first thread is released, and a remainder of the sock, including the foot portion of the sock, is knitted with the first thread.

Abstract: A disclosed process includes steps of heating a foamed material by irradiation with near infrared radiation having a wavelength between 0.78 and 1.40 ?m to form a heated material, forming the heated material with a forming tool to obtain a formed material, and cooling the formed material and demolding to obtain a final workpiece. The foamed material may be constructed as a composite ply construction including an outer material and a foamed core between the outer material. The foamed material may contain a poly(meth)acrylimde, a polypropylene or a highly-crosslinked polyurethane.

Abstract: Sock and gaiter knitted integrally in a single garment. The sock comprises a legging (1) and a foot of the sock (3). Coupled to the sock, there is a gaiter (2) along the sock circular section, between said legging (1) and said foot (3). Through the inherent elasticity of the sock (1, 3) and of the gaiter (2), namely in its circular section union, one can get an adaptable piece and able to keep in proper position to prevent the entry of foreign bodies or liquids, namely water, earth or sand, to the inside of the shoe, even under conditions of high effort and movement by the user. One can include adjusting means (4). This type of elastic adjustment, which prevents movements better than existing protections by being coupled to the legging (1) of the sock, allows superior sealing and maintains the comfort and safety of its user.

Abstract: Sock and gaiter knitted integrally in a single garment. The sock comprises a legging (1) and a foot of the sock (3). Coupled to the sock, there is a gaiter (2) along the sock circular section, between said legging (1) and said foot (3). Through the inherent elasticity of the sock (1, 3) and of the gaiter namely in its circular section union, one can get an adaptable piece and able to keep in proper position to prevent the entry of foreign bodies or liquids, namely water, earth or sand, to the inside of the shoe, even under conditions of high effort and movement by the user. One can include adjusting means (4). This type of elastic adjustment, which prevents movements better than existing protections by being coupled to the legging (1) of the sock, allows superior sealing and maintains the comfort and safety of its user.

Abstract: A disclosed process includes steps of heating a foamed material by irradiation with near infrared radiation having a wavelength between 0.78 and 1.40 ?m to form a heated material, forming the heated material with a forming tool to obtain a formed material, and cooling the formed material and demolding to obtain a final workpiece. The foamed material may be constructed as a composite ply construction including an outer material and a foamed core between the outer material. The foamed material may contain a poly(meth)acrylimde, a polypropylene or a highly-crosslinked polyurethane.

Abstract: The present invention relates to a sock with integrated biometric monitoring. The invention includes a biometric sensor system integrated into a sock with the ability to process and store the biometric data collected in order to provide useful information to the user, relating the user's biometric data to performance parameters of physical effort. The invention includes sensing integrated, on suitable supports (2), in the textile structure of the sock including temperature (1), heart beating and blood pressure (5) exerted by the foot of its user, to a processor (10, 11), signaling means (13) and interaction (14), to be interpreted and sent (12) to a mobile device (15) that stores data and allows the visualization of data. The invention includes textile integration of biometric monitoring devices through conductive yarns (3, 4, 6, 7) knitted with own sock and their connections to sensors, terminals (8, 9) and encapsulations.

Abstract: A hybrid thermoform-injection molding process for fusing labels during the molding process onto plastic parts having multiple contours and/or holes, different wall thickness and depths is presented. In the preferred embodiment, a label made of the same material as the plastic piece to which it is to be applied is fixed into a shape corresponding to that of the final desired shape through thermoforming. The label is then placed into a second mold where it is fused to plastic in an injection molding process to form a final product.

Abstract: An apparatus and process for fusing labels onto plastic parts having multiple contoirs and/or holes during the molding process is presented. According to the invention, a label having art work or wording on its interior surface and made of the same material as the plastic piece to which it is to be applied, is positioned onto a mold. Placement is accomplished through the use of a robotic arm having an insulated plate at its operational end to eliminate electrical charge transfer to the tool. The interior side of the label is insulated. An electrical charge is then applied to the front surface of the label enabling it to be positioned and held in place on an irregularly shaped mold. In the preferred embodiment, polypropylene is used for the label and the plastic layer.