Patents by Inventor Jorge Sousa
Jorge Sousa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220151758Abstract: The present invention relates to a bio-functionalized fibrous structure with a core/shell architecture for partial or total repair of human tendons or ligaments. The architecture based on a core/shell system grants to the fibrous structure a specific physical and mechanical behaviour when it is repeatedly mechanically loaded, as happens with a native tendon or ligament in constant usage in the human body. The core is based on several sub-components, namely braided structures parallelly assembled, which are enclosed by a braided shell. Additionally, a selective bio-functionalization of the two parts of the core/shell structure can be applied in order to selectively improve or avoid the in vivo cell adhesion.Type: ApplicationFiled: March 30, 2020Publication date: May 19, 2022Inventors: Maria Ascensao FERREIRA DA SILVA LOPES, Diana Raquel DOS SANTOS MORAIS, Rui Jorge SOUSA COSTA DE MIRANDA GUEDES, Raul Manuel ESTEVES DE SOUSA FANGUEIRO, Juliana Patricia CORREIA DA CRUZ, Tiago DE MELO SILVA RAMOS PEREIRA, Joao Manuel DA COSTA FERREIRA TORRES
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Patent number: 10092779Abstract: Oral care compositions comprising a capsules comprising flavoring and/or one or more active ingredients, and/or flavours, said capsules distributed in an orally acceptable vehicle or carrier.Type: GrantFiled: August 11, 2009Date of Patent: October 9, 2018Assignee: Colgate-Palmolive CompanyInventors: Jose Eder Fontana, Edilberto Lemos, Henrique Jorge Sousa Sales, Marcia Pereira
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Patent number: 9737579Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.Type: GrantFiled: July 22, 2016Date of Patent: August 22, 2017Assignees: Technophage, Investigacao E Desenvolvimento Em Biotecnologia, SA, Tecnifar—Industria Tecnica Farmaceutica, S.A.Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
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Patent number: 9682110Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophages F1245/05, F168/08, F170/08, F770/05, F197/08, F86/06, F87s/06 and F91a/06, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophages and/or isolated polypeptides and methods for the treatment and prevention of bacterial infection, either alone or in combination with other antibacterial therapies, e.g., antibiotics or other phage therapies.Type: GrantFiled: September 11, 2015Date of Patent: June 20, 2017Assignees: Technophage, Investigação E Desenvolvimento Em Biotechnologia, SA, Tecnifar-Indústria Técnia Farmacêutica, S.AInventors: Miguel Angelo Da Costa Garcia, Carlos Jorge Sousa De Sao Jose, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marcal Da Silva, Sara Ferreira Llorente Grancho Lourenco
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Publication number: 20160317590Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.Type: ApplicationFiled: July 22, 2016Publication date: November 3, 2016Inventors: Miguel Ångelo DA COSTA GARCIA, Carlos Jorge SOUSA DE SÃO JOSÉ, Clara Isabel RODRIGUES LEANDRO, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel MARTINS BARBOSA
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Patent number: 9399049Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.Type: GrantFiled: November 17, 2015Date of Patent: July 26, 2016Assignees: Technophage, Investigacao E Desenvolvimento Em Biotecnologia, SA, Tecnifar-Industria Tecnica Farmaceutica, S.A.Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
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Publication number: 20160074446Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.Type: ApplicationFiled: November 17, 2015Publication date: March 17, 2016Inventors: Miguel Ângelo DA COSTA GARCIA, Carlos Jorge SOUSA DE SÃO JOSÉ, Clara Isabel RODRIGUES LEANDRO, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel MARTINS BARBOSA
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Publication number: 20160022747Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophages F1245/05, F168/08, F170/08, F770/05, F197/08, F86/06, F87s/06 and F91a/06, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophages and/or isolated polypeptides and methods for the treatment and prevention of bacterial infection, either alone or in combination with other antibacterial therapies, e.g., antibiotics or other phage therapies.Type: ApplicationFiled: September 11, 2015Publication date: January 28, 2016Inventors: Miguel Angelo Da Costa Garcia, Carlos Jorge Sousa De Sao Jose, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marcal Da Silva, Sara Ferreira Llorente Grancho Lourenco
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Patent number: 9222077Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.Type: GrantFiled: September 19, 2011Date of Patent: December 29, 2015Assignees: Tecnifar—Industria Tecnica Farmaceutica, S.A., Technophage, Investigacao E Desenvolveimento Em Biotecnologia, SAInventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
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Patent number: 9134312Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophages F1245/05, F168/08, F170/08, F770/05, F197/08, F86/06, F87s/06 and F91a/06, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophages and/or isolated polypeptides and methods for the treatment and prevention of bacterial infection, either alone or in combination with other antibacterial therapies, e.g., antibiotics or other phage therapies.Type: GrantFiled: February 5, 2010Date of Patent: September 15, 2015Assignees: Tecnifar—Industria Tecnica Farmaceutica, S.A., Technophage, Investigação E Desenvolvimento Em Biotecnologia, SAInventors: Miguel Ängelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Sara Ferreira Llorente Grancho Lourenço
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Patent number: 9079845Abstract: The disclosed invention refers to a process for obtaining fatty acid alkyl esters, rosin acids and sterols from crude tall oil (CTO), which is characterized by the following steps: (a) reacting the free fatty acids present in the CTO with lower alcohols; (b) esterifying the sterols in the CTO with boric acid or transesterifying the sterols with a catalyst; (c) separating the fatty acid lower alkyl esters and rosin acids from the remaining sterol borate esters or sterol esters of fatty acids to produce a stream of sterol esters; (d) separating the fatty acid alkyl esters from the rosin acids to produce a first stream of fatty acid alky esters and a second stream of rosin acids; and (e) converting the sterol esters into the free sterols to produce a third stream of free sterols.Type: GrantFiled: February 20, 2004Date of Patent: July 14, 2015Assignee: Cognis IP Management GmbHInventors: Setsuo Sato, Henrique Jorge Sousa Sales, Hercules Peloggia, Peter Kempers, Sabine Both, Ulrich Schoerken, Thomas Wolf
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Publication number: 20140079671Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophage F387/08, F391/08, F394/08, F488/08, F510/08, F44/10, and F125/10, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophage and/or isolated polypeptides, as well as to methods for the treatment and prevention of bacterial infections using same, either alone or in combination with other antibacterial therapies, e.g., antibiotics and/or other phage therapies.Type: ApplicationFiled: September 19, 2011Publication date: March 20, 2014Applicants: TECHNOPHAGE, INVESTIGAÇÃO E DESENVOLVIMENTO EM BIOTECNOLOGIA, SA, TECNIFAR-INDÚSTRIA TÉCNICA FARMACÊUTICA, S.A.Inventors: Miguel Ângelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Ana Raquel Martins Barbosa
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Patent number: 8563504Abstract: The present invention is directed to isolated and chimeric polypeptides of bacteriophage origin having antibiotic activity and use thereof in the treatment and control of bacterial infections. Specifically, the present invention is directed to the use of a novel antibacterial polypeptide derived from bacteriophage F87s/06 and chimeric constructs thereof, and their use for the treatment and control of infections caused by gram-positive bacteria, including Staphylococcus aureus.Type: GrantFiled: October 9, 2009Date of Patent: October 22, 2013Assignee: Lusomedicamenta, S.A.Inventors: Miguel Ângelo da Costa Garcia, Madalena Maria Vilela Pimentel, Carlos Jorge Sousa de São José
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Publication number: 20120121669Abstract: Oral care compositions comprising a capsules comprising flavoring and/or one or more active ingredients, and/or flavours, said capsules distributed in an orally acceptable vehicle or carrier.Type: ApplicationFiled: August 11, 2009Publication date: May 17, 2012Applicant: Colgate-Palmolive CompanyInventors: Jose Eder Fontana, Edilberto Lemos, Henrique Jorge Sousa Sales, Marcia Pereira
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Publication number: 20120052048Abstract: The present invention is directed to the field of phage therapy for the treatment and control of bacterial infections. In particular, the present invention is directed to the novel bacteriophages F1245/05, F168/08, F170/08, F770/05, F197/08, F86/06, F87s/06 and F91a/06, isolated polypeptides thereof, compositions comprising one or more of the novel bacteriophages and/or isolated polypeptides and methods for the treatment and prevention of bacterial infection, either alone or in combination with other antibacterial therapies, e.g., antibiotics or other phage therapies.Type: ApplicationFiled: February 5, 2010Publication date: March 1, 2012Applicants: TECNIFAR-INDUSTRIA TECNICA FARMACEUTICA, S.A., TECHNOPHAGE INVESTIGACAO E DESENVOLVIMENTO EM BIOTECNOLOGIA SAInventors: Miguel Ängelo Da Costa Garcia, Carlos Jorge Sousa De São José, Clara Isabel Rodrigues Leandro, Filipa Maria Rodrigues Pardal Dias Antunes Marçal Da Silva, Sara Ferreira Llorente Grancho Lourenço
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Publication number: 20110230393Abstract: The present invention is directed to isolated and chimeric polypeptides of bacteriophage origin having antibiotic activity and use thereof in the treatment and control of bacterial infections. Specifically, the present invention is directed to the use of a novel antibacterial polypeptide derived from bacteriophage F87s/06 and chimeric constructs thereof, and their use for the treatment and control of infections caused by gram-positive bacteria, including Staphylococcus aureus.Type: ApplicationFiled: October 9, 2009Publication date: September 22, 2011Inventors: Miguel Angelo Da Costa Garcia, Madalena Maria Vilela Pimentel, Carlos Jorge Sousa de São José
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Patent number: 7700675Abstract: The invention relates to plasticizer compositions for polyvinyl chloride resins. A plasticized polyvinyl chloride resin contains (a) 100 parts by weight of at least one polyvinyl chloride resin and (b) 0.1 to 200 parts by weight of a plasticizer compounded with the polyvinyl chloride resin, wherein the plasticizer comprises (i) at least one isobutanol ester of a fatty acid with 8 to 24 carbon atoms, wherein, the fatty acid can be saturated or olefinically unsaturated, linear or branched and contain at least one epoxy group per molecule and (ii) at least one methyl ester of a fatty acid with 16 to 18 carbon atoms, wherein, the fatty acid can be saturated or olefinically unsaturated, linear or branched.Type: GrantFiled: December 6, 2002Date of Patent: April 20, 2010Assignee: Cognis Brazil LtdaInventors: Wanderson Bueno de Almeida, Katia Braga, Henrique Jorge Sousa Sales
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Patent number: 6104281Abstract: An RF tag has an enable/disable circuit connected to a critical part of an electronic object/circuit, e.g. a computer mother board. The critical part of the circuit is any circuit component and/or connection that can enable and/or disable the electric circuit operation. Signals are sent to the tag to change data in the tag memory which causes the enable/disable tag circuit to control the critical part to enable and disable the electric circuit. A system checks the status of the tag, e.g. the electronic circuit was paid for, before enabling the electronic circuit.Type: GrantFiled: November 12, 1998Date of Patent: August 15, 2000Assignee: Intermec IP, Corp.Inventors: Harley Kent Heinrich, Peter George Capek, Thomas Anthony Cofino, Daniel J. Friedman, Kevin Patrick McAuliffe, Paul Jorge Sousa, Brian John Hugh Walsh
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Patent number: 5995019Abstract: A method of selecting groups of radio frequency RF transponders (tags) for communication between a base station and the tags. The tags are selected into groups according to a physical attribute of the signal sent by the tags to the base station, or according to the physical response of the tags to a physical attribute of the signal sent from the base station to the tags. Communication with the tags is thereby simplified, and the time taken to communicate with the first tag is markedly reduced.Type: GrantFiled: July 6, 1998Date of Patent: November 30, 1999Assignee: Intermec I.P. CorpInventors: Trieu Can Chieu, Thomas Anthony Cofino, Harley Kent Heinrich, Paul Jorge Sousa, Li-Cheng Richard Zai
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Patent number: 5874902Abstract: An RF tag has an enable/disable circuit connected to a critical part of an electronic object/circuit, e.g. a computer mother board. The critical part of the circuit is any circuit component and/or connection that can enable and/or disable the electric circuit operation. Signals are sent to the tag to change data in the tag memory which causes the enable/disable tag circuit to control the critical part to enable and disable the electric circuit. A system checks the status of the tag, e.g. the electronic circuit was paid for, before enabling the electronic circuit.Type: GrantFiled: July 29, 1996Date of Patent: February 23, 1999Assignee: International Business Machines CorporationInventors: Harley Kent Heinrich, Peter George Capek, Thomas Anthony Cofino, Daniel J. Friedman, Kevin Patrick McAuliffe, Paul Jorge Sousa, Brian John Hugh Walsh