Patents by Inventor Jorge TOLEDO ALONSO

Jorge TOLEDO ALONSO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant vaccine against proliferative enteropathy in animals
    Patent number: 11661444
    Abstract: The present invention relates to a recombinant vaccine against Lawsonia intracellularis, based on a recombinant synthetic chimeric variant of membrane proteins and invasins of said bacteria. In addition, the invention discloses synthetic nucleotide sequences encoding said protein variants, recombinant proteins as such, an expression cassette of said synthetic protein antigens, a transformed cell, and a method for producing said antigens, demonstrating the antigenicity and protective potential thereof against the pathogen Lawsonia intracellularis.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: May 30, 2023
    Assignee: UNIVERSIDAD DE CONCEPCIÓN
    Inventors: Raquel Montesino Segui, Jorge Toledo Alonso, Alvaro Ruiz Garrido, Oliberto Sanchez Ramos, Nicolas Gutierrez Mella, Omar Farnos Villar, Angela Hidalgo Gajardo, Eduardo Ramos Delgado, Marcelo Cortez San Martin
  • RECOMBINANT BOVINE FOLLICLE-STIMULATING HORMONE, COMPOSITION COMPRISING THE SAME, AND METHOD TO INDUCE SUPEROVULATION AND ESTRUS SYNCHRONIZATION IN BOVINES USING SAID HORMONE
    Publication number: 20210253660
    Abstract: The present invention relates to the technical field of Biotechnology and the obtaining of molecules by recombinant DNA technology, in particular it refers to a synthetic polynucleotide sequence encoding a single-chain recombinant bovine follicle-stimulating hormone, comprising a first polynucleotide enconding the beta subunit of the Bos taurus follicle-stimulating hormone having sequence SEQ ID No. 1, or a variant thereof with at least 85% sequence identity therewith; a second polynucleotide encoding the alpha subunit of the Bos taurus follicle-stimulating hormone having sequence SEQ ID No. 2 or a variant thereof with at least 85% sequence identity therewith; and a third polynucleotide linking said first and second polynucleotides, which encodes a spacer sequence derived from human keratin 10 having sequence SEQ ID No. 3 or a variant.
    Type: Application
    Filed: May 16, 2019
    Publication date: August 19, 2021
    Inventors: Oliberto SANCHEZ RAMOS, Jorge TOLEDO ALONSO, Florence HUGUES SALAZAR, Ignacio CABEZAS ÁVILA, Rita Paulina CERRO GARRIDO, Natalie Carolina PARRA PEREIRA, Jannel ACOSTA ALBA, Kaio Cesar SIMIANO TAVARES, Leonardo TONDELLO MARTINS, Saul GAUDENCIO NETO
  • RECOMBINANT VACCINE AGAINST PROLIFERATIVE ENTEROPATHY IN ANIMALS
    Publication number: 20210221855
    Abstract: The present invention relates to a recombinant vaccine against Lawsonia intracellularis, based on a recombinant synthetic chimeric variant of membrane proteins and invasins of said bacteria. In addition, the invention discloses synthetic nucleotide sequences encoding said protein variants, recombinant proteins as such, an expression cassette of said synthetic protein antigens, a transformed cell, and a method for producing said antigens, demonstrating the antigenicity and protective potential thereof against the pathogen Lawsonia intracellularis.
    Type: Application
    Filed: August 28, 2018
    Publication date: July 22, 2021
    Inventors: Raquel MONTESINO SEGUI, Jorge TOLEDO ALONSO, Alvaro RUIZ GARRIDO, Oliberto SANCHEZ RAMOS, Nicolas GUTIERREZ MELLA, Omar FARNOS VILLAR, Angela HIDALGO GAJARDO, Eduardo RAMOS DELGADO, Marcelo CORTEZ SAN MARTIN