Patents by Inventor Jorgen Scheel-Kruger

Jorgen Scheel-Kruger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triple monoamine reuptake inhibitors for the treatment of chronic pain
    Patent number: 7459464
    Abstract: The present invention relates to the use of triple monoamine reuptake inhibitors for the treatment of chronic pain.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: December 2, 2008
    Assignee: Neurosearch A/S
    Inventors: Jørgen Scheel-Krüger, Gordon John Blackburn-Munro
  • 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7407970
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: August 5, 2008
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Birgitte L. Eriksen, Elsebet Østergaard Nielsen, Jørgen Scheel-Krüger, Gunnar M. Olsen
  • Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080176856
    Abstract: This invention relates to novel alkyl substituted piperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: July 24, 2008
    Inventors: Dan Peters, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Jorgen Scheel-Kruger
  • Novel Alkyl Substituted Homopiperazine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080132489
    Abstract: This invention relates to novel alkyl substituted homopiperazine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: February 9, 2006
    Publication date: June 5, 2008
    Inventors: Dan Peters, Bjarne H. Dahl, Gunnar M. Olsen, Elsebet Ostergaard Nielsen, Jorgen Scheel-Kruger, John Paul Redrobe
  • Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
    Patent number: 7381733
    Abstract: The present invention relates to the use of tropane derivatives having dopamine reuptake inhibitor activity for the treatment of diseases associated with reduced blood flow to the brain or with instances of a temporary break in blood supply to the brain, such as ischemic diseases.
    Type: Grant
    Filed: November 28, 2002
    Date of Patent: June 3, 2008
    Assignee: Neurosearch A/S
    Inventors: Jørgen Scheel-Krüger, Lars Christian B. Rønn
  • 3,8-Substituted 8-Aza-Bicyclo[3.2.1]Octane Derivatives and Their Use as Monomine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20080004252
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: January 11, 2006
    Publication date: January 3, 2008
    Inventors: Dan Peters, Bjarne Dahl, Gunnar Olsen, Elsebet Nielsen, Jorgen Scheel-Kruger, John Redrobe
  • Novel Chromen-2-One Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20070232666
    Abstract: This invention relates to novel chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: September 28, 2005
    Publication date: October 4, 2007
    Inventors: Dan Peters, Gunnar Olsen, Jorgen Scheel-Kruger, Elsebet Nielsen
  • Novel Alkyl Substituted Piperidine Derivatives as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20070232659
    Abstract: This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: October 4, 2007
    Inventors: Dan Peters, Gunnar Olsen, Elsebet Nielsen, Jorgen Scheel-Kruger
  • Novel 9-Aza-Bicyclo[3.3.1]Nonane Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors
    Publication number: 20070232641
    Abstract: This invention relates to novel 9-aza-bicyclo[3.3.1]nonane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: October 4, 2007
    Inventors: Dan Peters, Gunnar Olsen, Elsebet Nielsen, Jorgen Scheel-Kruger
  • 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7250425
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: July 31, 2007
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Elsebet Østergaard Nielsen, Gunnar M. Olsen, Jørgen Scheel-Kruger
  • 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Patent number: 7247643
    Abstract: This invention relates to novel 8-aza-bicyclop[3.2.1]octane derivatives useful as monoamine neurotransmitter re-up-take inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: February 10, 2004
    Date of Patent: July 24, 2007
    Assignee: NeuroSearch A/S
    Inventors: Dan Peters, Elsebet Østergaard Nielsen, Gunnar M. Olsen, Jørgen Scheel-Krüger
  • Novel alkyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20070167487
    Abstract: This invention relates to novel alkyl substituted piperidine derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 14, 2005
    Publication date: July 19, 2007
    Inventors: Dan Peters, Gunnar Olsen, Elscbet Nielspn, Jorgen Scheel-Kruger, Birgitte Eriksen
  • Compounds and their use as positive AMPA receptor modulators
    Patent number: 7235548
    Abstract: The invention provides novel compounds represented by the general formula compound represented by the formula: wherein the bond represented by the broken line may be a single, a double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O or CH2; Y represents —CH(R4)—, —N(R4)— or —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application The compounds are useful as positive modulators of the AMPA-receptor.
    Type: Grant
    Filed: August 18, 2003
    Date of Patent: June 26, 2007
    Assignee: NeuroSearch A/S
    Inventors: Alex Haaht Gouliaev, Mogens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Jorgen Scheel-Kruger, Gunnar M. Olsen, Elsesbet Ostergaard Nielsen
  • Benzothiazine derivatives, their preparation and use
    Patent number: 7199118
    Abstract: This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and their use in therapy.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: April 3, 2007
    Assignee: NeuroSearch A/S
    Inventors: Alex Haahr Gouliaev, Morgens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Karin Sandager Nielsen, Barbara Hartz, Jorgen Scheel-Kruger
  • Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20060148847
    Abstract: This invention relates to novel 8-aza-bicyclo[[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: February 10, 2004
    Publication date: July 6, 2006
    Inventors: Dan Peters, Elsebert Nielsen, Gunnar Olsen, Jorgen Scheel-Kruger
  • Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20060142331
    Abstract: This invention relates to novel 8-aza-bicyclo[3.2.1]octane derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: June 18, 2004
    Publication date: June 29, 2006
    Inventors: Dan Peters, Birgitte Eriksen, Elsebet Nielsen, Jorgen Scheel-Kruger, Gunnar Olsen
  • 8-Aza-Bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
    Publication number: 20060122218
    Abstract: This invention relates to novel 8-aza-bicyclop[3.2.1]octane derivatives useful as monoamine neurotransmitter re-up-take inhibitors. In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Application
    Filed: February 10, 2004
    Publication date: June 8, 2006
    Inventors: Dan Peters, Elsebet Ostergaard, Gunnar Olsen, Jorgen Scheel-Kruger
  • Triple monoamine reuptake inhibitors for the treatment of chronic pain
    Publication number: 20050239824
    Abstract: The present invention relates to the use of triple monoamine reuptake inhibitors for the treatment of chronic pain.
    Type: Application
    Filed: May 27, 2003
    Publication date: October 27, 2005
    Inventors: Jorgen Scheel-Kruger, Gordon Blackburn-Munro
  • Compounds and their use as positive AMPA receptor modulators
    Patent number: 6943159
    Abstract: The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O of CH2; Y represents —CH(R4)—, —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: September 13, 2005
    Assignee: Neurosearch A/S
    Inventors: Alex Haahr Gouliaev, Mogens Larsen, Thomas Varming, Claus Mathiesen, Tina Holm Johansen, Jørgen Scheel-Krüger, Gunnar M. Olsen, Elsebet Østergaard Nielsen
  • Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
    Publication number: 20050020621
    Abstract: The present invention relates to the use of tropane derivatives having dopamine reuptake inhibitor activity for the treatment of diseases associated with reduced blood flow to the brain or with instances of a temporary break in blood supply to the brain, such as ischemic diseases.
    Type: Application
    Filed: November 28, 2002
    Publication date: January 27, 2005
    Inventors: Jorgen Scheel-Kruger, Lars Christian Ronn