Patents by Inventor Jori E. Wehrmuller

Jori E. Wehrmuller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered synthase for production of tryptophan derivatives and intransigent substrates
    Patent number: 11873518
    Abstract: This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: January 16, 2024
    Assignee: California Institute of Technology
    Inventors: David K. Romney, Javier Murciano Calles, Jori E. Wehrmuller
  • ENGINEERED SYNTHASE FOR PRODUCTION OF TRYPTOPHAN DERIVATIVES AND INTRANSIGENT SUBSTRATES
    Publication number: 20220259581
    Abstract: This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
    Type: Application
    Filed: April 19, 2022
    Publication date: August 18, 2022
    Applicant: California Institute of Technology
    Inventors: David K. Romney, Javier Murciano Calles, Jori E. Wehrmuller
  • Engineered synthase for production of tryptophan derivatives and intransigent substrates
    Patent number: 11332729
    Abstract: This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 17, 2022
    Assignee: California Institute of Technology
    Inventors: David K. Romney, Javier Murciano Calles, Jori E. Wehrmuller
  • ENGINEERED SYNTHASE FOR PRODUCTION OF TRYPTOPHAN DERIVATIVES AND INTRANSIGENT SUBSTRATES
    Publication number: 20180057806
    Abstract: This disclosure relates to modified tryptophan synthase and more particularly to modified beta-subunits of tryptophan synthase. The disclosure further relates to cells expressing such modified subunits and methods of producing non-canonical amino acids.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 1, 2018
    Inventors: David K. Romney, Javier Murciano Calles, Jori E. Wehrmuller