Patents by Inventor Joris Jan Heus

Joris Jan Heus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C1 Inhibitor produced in the milk of transgenic non-human mammals
    Patent number: 7067713
    Abstract: The invention provides transgenic nonhuman mammals expressing C1 inhibitor in their milk. The C1 inhibitor is useful in treating patients with hereditary angioedema or patients requiring immunosuppression.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: June 27, 2006
    Assignee: Pharming Intellectual Property B.V.
    Inventors: Jan Henricus Nuijens, Henricus Antonius Van Veen, Frank Robert Pieper, Joris Jan Heus
  • Human acid alpha glucosidase gene and bovine alpha-S1 casein gene sequences
    Patent number: 6858425
    Abstract: The invention provides polynucleotide sequences from the human acid alpha glucosidase gene and the bovine alpha S1 casein gene. These sequences are useful for designing transgenes for expression of human acid alpha glucosidase in the milk of transgenic animals. The sequences are also useful for design of primers and probes, and for computerized methods of sequence comparison.
    Type: Grant
    Filed: December 3, 1999
    Date of Patent: February 22, 2005
    Assignee: Genzyme Corporation
    Inventor: Joris Jan Heus