Abstract: The present invention relates to compositions comprising thioridazine, and derivatives thereof, together with antibacterials. These compositions have been found greatly enhance the activity of many classes of antibacterials, allowing the antibacterials to be administered at significantly lower doses. The thioridazine and the antibacterial act synergistically by pacifying the bacteria to the antibacterials. This synergistic affect lowering the inhibitory or effective concentration of the antimicrobials is most pronounced with the levorotatory isomer of thioridazine compared to the racemic or dextrorotatory isomer.

Abstract: A sealing ring of an elastic material is adapted to be applied to the spigot end of a pipe under expansion of the diameter of the ring. To obtain a particularly effective seal without any risk of overloading of the elastic material, neither during insertion into a pipe socket, assembling of the pipes nor later on as a consequence of oblique loads on the pipes, the sealing ring has a sealing member which consists of a hose (1) with a solid compression member (2) which is disposed inside the hose and is connected to the hose (1) through a flap (3). The flap has moreover an elongation (4) which can serve as a finger grip for the application of the sealing ring to the spigot end and counteract twisting of the sealing ring when the pipes are assembled.